GEO DataSets

(Submitter supplied) We investigated the effects of diabetes, physical training, and their combination on the gene expression of cardiac muscle. Mice were divided to control (C), training (T), streptozotocin-induced diabetic (D), and diabetic training (DT) groups. Training groups performed 1, 3, or 5 weeks of endurance training on a motor-driven treadmill. Muscle samples from T and DT groups together with respective controls were collected 24 hours after the last training session. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS2335

Platform:

GPL81

12 Samples

Download data: CEL, EXP

(Submitter supplied) Experiment protocol: Experiment was performed on 10 to 15 weeks old male NMRI mice (Harlan, Holland) housed in standard conditions (temperature 22°C, humidity 60 ± 10 %, artificial light from 8.00 am to 8.00 pm, normally 5 animals per cage). Animals had free access to tap water and food pellets (R36, Labfor, Stockholm, Sweden). Animals were randomly divided into healthy and diabetic groups. The diabetic group received a single peritoneal injection of streptozotocin (STZ, Sigma-Aldrich, France, 180 mg/kg) dissolved in sodium citrate buffer solution (0.1 mol/l, pH 4.5) to induce experimental diabetes similar to type 1. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS1541

Platform:

GPL81

12 Samples

Download data: CEL, EXP

Analysis of experimental type 1 diabetic cardiac muscles of NMRI males subjected to endurance training for up to 5 weeks. Diabetes induced by a single peritoneal injection of streptozotocin.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 disease state, 2 protocol, 3 time sets

Platform:

GPL81

Series:

GSE4616

12 Samples

Download data: CEL, EXP

Analysis of experimental type 1 diabetic skeletal muscle subjected to endurance training. Diabetic muscle atrophy is accompanied by changes in the extracellular matrix (ECM). Results suggest the diabetes-induced decrease in gene expression of ECM proteins is partially attenuated by training.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 disease state, 2 protocol, 3 time sets

Platform:

GPL81

Series:

GSE1659

12 Samples

Download data: CEL, EXP

(Submitter supplied) Background: Exercise has a positive effect on overall health. This study was performed to get an overview of the effects of mixed exercise training on skeletal muscl

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL11532

36 Samples

Download data: CEL

(Submitter supplied) To provide insights into the role of Ankrd2 in the pathways controlling myogenic differentiation, the gene networks that are disturbed in Ankrd2 knockout or overexpressing primary cells were explored during differentiation. Ankrd2 plays an important role in myogenic differentiation by modulating the activity of its interacting partners (i.e p53). Since Ankrd2 binds to numerous transcription factors many signaling pathways remained to be explored to determine the functional significance of crosstalk between Ankrd2 and the activation of transcriptional programmes that regulate muscle remodeling. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL10787

36 Samples

Download data: TXT