GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS2227

Platform:

GPL2987

21 Samples

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(Submitter supplied) The mouse embryonic stem cell’s differentiation was guided by several treatments, and each stage of differentiation was examined. Keywords: development stage

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2987

12 Samples

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(Submitter supplied) Embryoid Bodies were dissociated and plated onto tissue culture dish in DMEM with fetal bovine serum and antibiotics for 4, 8, 12, 15, 21 day. Keywords: development stage

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2987

12 Samples

Download data

Comparison of cells induced to differentiate into dopaminergic neurons by guided differentiation (GD) to those induced to differentiate into embryoid bodies (EBs) by random differentiation (RD). Cells at 3 stages of differentiation in the GD model and days 4 to 21 EBs in the RD model compared.

Organism:

Mus musculus

Type:

Expression profiling by array, log ratio, 7 development stage, 2 growth protocol sets

Platform:

GPL2987

Series:

GSE5459

21 Samples

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(Submitter supplied) During development of the mammalian central nervous system (CNS), neurons and glial cells (astrocytes and oligodendrocytes) are generated from common neural precursor cells (NPCs). However, neurogenesis precedes gliogenesis, which normally commences at later stages of fetal telencephalic development. Astrocyte differentiation of mouse NPCs at embryonic day (E) 14.5 (relatively late gestation) is induced by activation of the transcription factor STAT3, whereas at E11.5 (mid-gestation) NPCs do not differentiate into astrocytes even when stimulated by STAT3-activating cytokines such as leukemia inhibitory factor (LIF). more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

4 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2926

Platform:

GPL887

77 Samples

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(Submitter supplied) Little is known about the global transcriptional program underlying megakaryocytic (Mk) differentiation, maturation, and apoptosis. Using DNA microarrays and Q-RT-PCR, we examined the transcriptional profile of Mk differentiation human CD34-positive hematopoietic stem and progenitor cells cultured with thrombopoietin, interleukin-3, and Flt3-ligand. The goal this study was to identify genes involved in the various facets of Mk differentiation including commitment, polyploidization, proplatelet formation, and apoptosis. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL887

36 Samples

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(Submitter supplied) Little is known about the global transcriptional program underlying megakaryocytic (Mk) differentiation, maturation, and apoptosis. Using DNA microarrays and Q-RT-PCR, we examined the transcriptional profile of phorbol-ester-induced Mk differentiation of the megakaryoblastic CHRF-288-11 (CHRF) cell line – a model system for investigating megakaryopoiesis. The goals of this study were to (1) verify the megakaryocytic nature of the CHRF cell line at the transcriptional level, and (2) extract novel insights into the key facets of Mk maturation including polyploidization, proplatelet formation, and apoptosis. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL887

41 Samples

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Temporal analysis of phorbol ester-treated CHRF-288-11 megakaryoblastic cells induced to undergo megakaryocytic (Mk) differentiation and primary Mk (PriMk) cells derived from cytokine-treated CD34+ peripheral blood cells. Results provide insight into molecular mechanisms underlying megakaryopoiesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, log e ratio, 4 agent, 2 cell line, 13 time sets

Platform:

GPL887

Series:

GSE8914

77 Samples

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(Submitter supplied) The orphan nuclear receptor Nurr1 has been shown to be critical for the development of ventral midbrain dopaminergic neurons. Consequently, the development of ES cells overexpressing Nurr1 has raised hope for the development of cell replacement therapies for Parkinson's Disease to replace degenerated dopaminergic neurons. However, the molecular consequences of Nurr1 on gene expression in these cells remain unknown. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS2027

Platform:

GPL81

4 Samples

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Expression profiling of neural stem cell lines overexpressing the orphan nuclear receptor Nurr1. Nurr1 is critical for the development of the ventral midbrain dopaminergic neurons, the cells primarily lost in Parkinson's disease.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 genotype/variation, 2 other sets

Platform:

GPL81

Series:

GSE3571

4 Samples

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(Submitter supplied) An 11-point time course study on differentiating embryoid bodies from a murine J1 embryonic stem cell line. The time course includes 0 hr, 6 hr, 12 hr, 18 hr, 24 hr, 36 hr, 48 hr, 4 days, 7 days, 9 days and 14 days. Keywords: Time course

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS2668 GDS2669

Platforms:

GPL339 GPL340

66 Samples

Download data: CEL, EXP

(Submitter supplied) An 11-point time course study comparing V6.5 embryonic stem cells versus embryoid bodies. Time course 0 hours, 6 hours, 12 hours, 18 hours, 24 hours, 36 hours, 48 hours, 4 days, 7 days, 9 days, and 14 days. Keywords: other

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS2671 GDS2672

Platforms:

GPL339 GPL340

66 Samples

Download data: CEL, EXP

(Submitter supplied) An 11-point time course study comparing R1 embryonic stem cells versus embryoid bodies. Time course 0 hours, 6 hours, 12 hours, 18 hours, 24 hours, 36 hours, 48 hours, 4 days, 7 days, 9 days, and 14 days. Keywords: other

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS2666 GDS2667

Platforms:

GPL340 GPL339

66 Samples

Download data: CEL, EXP

Analysis of V6.5 embryonic stem cells differentiating into embryoid bodies in vitro. Cells examined at various time points up to 14 days after inducing differentiation. Results provide insight into the molecular mechanisms that drive embryonic stem cell differentiation.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 11 time sets

Platform:

GPL340

Series:

GSE3231

33 Samples

Download data: CEL, EXP

Analysis of V6.5 embryonic stem cells differentiating into embryoid bodies in vitro. Cells examined at various time points up to 14 days after inducing differentiation. Results provide insight into the molecular mechanisms that drive embryonic stem cell differentiation.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 11 time sets

Platform:

GPL339

Series:

GSE3231

33 Samples

Download data: CEL, EXP

Analysis of J1 embryonic stem cells differentiating into embryoid bodies in vitro. Cells examined at various time points up to 14 days after inducing differentiation. Results provide insight into the molecular mechanisms that drive embryonic stem cell differentiation.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 11 time sets

Platform:

GPL340

Series:

GSE3749

33 Samples

Download data: CEL, EXP

Analysis of J1 embryonic stem cells differentiating into embryoid bodies in vitro. Cells examined at various time points up to 14 days after inducing differentiation. Results provide insight into the molecular mechanisms that drive embryonic stem cell differentiation.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 11 time sets

Platform:

GPL339

Series:

GSE3749

33 Samples

Download data: CEL, EXP

Analysis of R1 embryonic stem cells differentiating into embryoid bodies in vitro. Cells examined at various time points up to 14 days after inducing differentiation. Results provide insight into the molecular mechanisms that drive embryonic stem cell differentiation.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 11 time sets

Platform:

GPL340

Series:

GSE2972

33 Samples

Download data: CEL, EXP

Analysis of R1 embryonic stem cells differentiating into embryoid bodies in vitro. Cells examined at various time points up to 14 days after inducing differentiation. Results provide insight into the molecular mechanisms that drive embryonic stem cell differentiation.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 11 time sets

Platform:

GPL339

Series:

GSE2972

33 Samples

Download data: CEL, EXP