Similar studies for GEO DataSets (Select 200057780) - GEO DataSets

Links from GEO DataSets

Items: 20

Select item 2000577801.

New global miRSeq analysis of “miRNome”: the example of PTC and nodal metastases

(Submitter supplied) The set of expressed microRNAs in a given cell type, or “miRNome”, can be explored under many different aspects. Many studies report modulations of the miRNome in a wide variety of cancers. Papillary thyroid cancer is the most prevalent type of endocrine cancer. The presence of nodal metastases increases the risk of recurrence and mortality. In our study, we performed microRNA deep sequencing (miRSeq) of 3 PTC, their matching normal tissues and nodal metastases and designed a new bioinformatic framework to analyze variations of the different aspects of the miRNome: expression profile, isomiRs and non-templated additions distributions, mutation or A-to-I RNA-editing. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL11154
9 Samples

Download data: FA, TXT

Series

Accession:: GSE57780

ID:: 200057780

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001298802.

miRNA and mRNA expression profiles in non-aggressive, invasive and metastatic papillary thyroid cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array; Expression profiling by array

Platforms:: GPL19117 GPL15207
18 Samples

Download data: CEL

Series

Accession:: GSE129880

ID:: 200129880

Select item 2001298793.

mRNA expression profiles in non-aggressive, invasive and metastatic papillary thyroid cancer

(Submitter supplied) Paillary thyroid cancer (PTC) is the most common type of thyroid malignancy. Extrathyroidal invasion (ETİ), lymph node metastasis, and distance organ metastasis is poor prognostic factor in PTC. The metastasis is still a leading cause of papillary thyroid cancer death. The early detection of metastatic signature is crucial for identification of thyroid cancer prognosis and personalized therapeutic strategies. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL15207
9 Samples

Download data: CEL, XLSX

Series

Accession:: GSE129879

ID:: 200129879

Select item 2001298784.

miRNA expression profiles in non-aggressive, invasive and metastatic papillary thyroid cancer

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL19117
9 Samples

Download data: CEL, XLSX

Series

Accession:: GSE129878

ID:: 200129878

Select item 2000157405.

MicroRNA signature of thyroid tumors of uncertain malignancy

(Submitter supplied) Well-differentiated tumours (WDT) of the thyroid gland can be difficult to diagnose. Focal nuclear clearing can be suggestive of a papillary thyroid carcinoma (PTC), while questionable vascular or capsular penetration may raise the possibility of diagnosis of a follicular thyroid carcinoma (FTC). The recently proposed term “thyroid tumours of uncertain malignant potential” (TT-UMP) defines cases showing inconclusive morphological evidence of malignancy. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL4717
89 Samples

Download data: GPR

Series

Accession:: GSE15740

ID:: 200015740

Select item 2000935226.

Microarray Profiling of Circular RNAs in Human Papillary Thyroid Carcinoma

(Submitter supplied) Background: Non-coding circular RNAs (circRNAs) have displayed dysregulated expression in several human cancers. Here, we profiled the circRNA expression of papillary thyroid carcinoma (PTC) tumors to improve our understanding of PTC pathogenesis as well as to identify potential circRNA biomarkers for PTC.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL19978
18 Samples

Download data: TXT

Series

Accession:: GSE93522

ID:: 200093522

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001488487.

microRNA expression profiling of paired primary and lymph node metastatic breast cancer patients, and gene expression profiling of MDA-MB-231 cells transfected with hsa-miR-205-5p and hsa-miR-214-3p compared to scrambled miRNA precursors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array; Expression profiling by array

Platforms:: GPL17077 GPL21576
30 Samples

Download data: TXT

Series

Accession:: GSE148848

ID:: 200148848

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001488478.

Gene expression profiling of MDA-MB-231 cells transfected with hsa-miR-205-5p and hsa-miR-214-3p compared to scrambled miRNA precursors

(Submitter supplied) We have employed whole genome microarray to identify changes in gene expression in MDA-MB-231 cells transfected with hsa-miR-205-5p and hsa-miR-214-3p compared to scrambled miRNA precursors at 72 hours after transfection.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17077
6 Samples

Download data: TXT

Series

Accession:: GSE148847

ID:: 200148847

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001488469.

microRNA expression profiling of paired primary and lymph node metastatic breast cancer patients

(Submitter supplied) Extracted total RNA from FFPE tissue were used for RNA labeling and hybridization on to the Agilent Human SurePrint 8 × 60k v16 miRNA microarray chip according to the manufacturer's protocol.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL21576
24 Samples

Download data: TXT

Series

Accession:: GSE148846

ID:: 200148846

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008352010.

Genome-wide expression screening discloses long noncoding RNAs involved in thyroid carcinogenesis

(Submitter supplied) Context: Long non-coding RNAs (lncRNAs) regulate pathological processes, yet their potential roles in papillary thyroid carcinoma (PTC) are poorly understood. Objective: To profile transcriptionally dysregulated lncRNAs in PTC and identify lncRNAs associated with clinicopathological characteristics.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
24 Samples

Download data: GTF, TXT

Series

Accession:: GSE83520

ID:: 200083520

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20007318211.

miRNA expression profiling of snap-frozen primary papillary thyroid carcinomas (PTC) and normal thyroids

(Submitter supplied) The purpose of this study was to identify de-regulated miRNAs in human papillary thyroid carcinoma (PTC). To this aim miRNA expression profiles of PTCs and normal thyroid samples were compared. Tissue specimens were selected by an expert pathologist. Details about the histological type of tumor samples are provided.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL20194
24 Samples

Download data: TXT

Series

Accession:: GSE73182

ID:: 200073182

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005090112.

Expression profiling identifies deregulated pathways and top diagnostic markers in papillary thyroid carcinoma

(Submitter supplied) Expression microarray was used to compare 57 PTC with a reference sample (pool of 9 adjacent normal thyroid tissue) and 4 PTC against 4 matched adjacent normal thyroid tissue. A quality control filter was applied based on Feature Extraction flags (empty spaces replacing values)

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL13607
65 Samples

Download data: TXT

Series

Accession:: GSE50901

ID:: 200050901

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20006678313.

Genome-wide analysis of long noncoding RNA expression profile in papillary thyroid carcinoma

(Submitter supplied) Long noncoding RNAs (lncRNAs) have been proved to play important roles in cancer biology. To understand their expression profile and potential functions in papillary thyroid carcinoma (PTC), we investigated the lncRNA and mRNA expression in PTC and paired adjacent noncancerous thyroid tissues using microarray analysis.

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platform:: GPL19850
10 Samples

Download data: TXT

Series

Accession:: GSE66783

ID:: 200066783

Select item 20008696114.

Integrated data analysis reveals distinct drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas

(Submitter supplied) Multiple joint data, including methylome, transcriptomic, BRAF V600E mutation results and clinical features, aiming to identify molecular drivers in papillary thyroid carcinomas.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
82 Samples

Download data: IDAT

Series

Accession:: GSE86961

ID:: 200086961

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20012465315.

Small RNA deep sequencing of human thyroid tumors.

(Submitter supplied) Small RNAs of 49 thyroid tissues were extracted and isolated to investigate the correlation of miRNome profiles with specific clinic-pathological and molecular features of the tumors.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL11154
49 Samples

Download data: TXT

Series

Accession:: GSE124653

ID:: 200124653

PubMed Similar studies SRA Run Selector

Select item 20012368016.

Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells

(Submitter supplied) We explored alternative splicing events upon hsa-miR-139-5p/HNRNPF axis regulation in our cell system using the Multivariate Analysis of Transcript Splicing (rMATS) computational tool (https://doi.org/10.1073/pnas.1419161111). Differential analysis of major splicing outcomes (skipped exon, alternative 5’/3’ splice, mutually exclusive exons and retained intron) revealed a total of 174 events significantly activated or repressed (FDR<0.05) upon HNRNPF regulation.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
12 Samples

Download data: TXT

Series

Accession:: GSE123680

ID:: 200123680

Select item 20011736617.

New and subgroup-specific miRNAs and miRNA-offset RNA unraveled by RNA-sequencing in multiple myeloma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; synthetic construct

Type:: Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:: GPL11154 GPL25329
60 Samples

Download data: CEL

Series

Accession:: GSE117366

ID:: 200117366

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20011736518.

New and subgroup-specific miRNAs and miRNA-offset RNA unraveled by RNA-sequencing in multiple myeloma [miRNA-Seq]

(Submitter supplied) Microarray analysis of the miRNome in multiple myeloma (MM) has unraveled the differential expression of miRNAs in cytogenetic subgroups, their involvement in the tumor biology and their effectiveness in prognostic models. Herein, we provide a view of small RNA transcriptional landscape in MM at a higher definition, exploiting the possibilities offered by small RNA-sequencing (sRNA-seq), including improved detection of known/new mature species and accurate investigation of isomiRs and miRNA-offset RNAs (moRNAs). more...