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Links from GEO DataSets

Items: 6

1.

Genome-wide transcript analysis of ErbB2-induced tumors from different tumor-initiating cells

(Submitter supplied) ErbB2-induced mouse mammary tumors can originate from different mammary epithelial cells, including both basal epithelial cells and luminal progenitors. Here we used the tumors from basal cells or luminal progenitors to compare the difference in transcripts.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL18752
12 Samples
Download data: TXT
Series
Accession:
GSE64487
ID:
200064487
2.

Comparative Analysis of MMTV-neu tumors, preneoplastic MMTV-neu mammary gland, and Wild-type controls

(Submitter supplied) To identify early events of erbB2-induced mammary tumorigenesis, we compared datasets from 14 genechip experiments including MMTV-neu tumors, preneoplastic neu mammary gland (adjacent neu), and age-matched, wild-type control mammary glands Keywords = transgenic mouse Keywords = MMTV-neu Keywords = erbB2 Keywords = HER2 Keywords = mammary tumor Keywords: ordered
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS1222
Platform:
GPL81
14 Samples
Download data
Series
Accession:
GSE2528
ID:
200002528
3.
Full record GDS1222

Mammary tumorigenesis in MMTV-neu model

Analysis of cancer progression by profiling of preneoplastic mammary glands and tumors of MMTV-neu animals. Activated neu allele placed under the control of mammary tumor virus promoter to enable mammary specific expression. Results provide insight into the early events of Neu induced tumorigenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 disease state, 2 genotype/variation sets
Platform:
GPL81
Series:
GSE2528
14 Samples
Download data
4.

The TLR2 pathway is required for self-renewal of mammary cancer initiating cells

(Submitter supplied) In the past few years, mammary cancer initiating cells (CICs) have been identified in mouse and human as a subpopulation of tumor cells that selectively posses tumor initiation and self-renewal capacity and the ability to give rise to bulk populations of non-tumorigenic cancer cells progeny through differentiation. They could also be responsible for tumor progression, metastasis, resistance to therapy and recurrence. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6887
12 Samples
Download data: TXT
Series
Accession:
GSE26527
ID:
200026527
5.

Multipotent mammary cancer stem cells integrate stem cell and clonal expansion theories of tumor progression

(Submitter supplied) The diversity of human breast cancer subtypes has led to the hypothesis that breast cancer is a number of different diseases arising from cells at various stages of differentiation. We have derived clonal multipotent metastatic mammary cancer stem cells from the polyomavirus middle T mouse model of breast cancer, that can differentiate into luminal, myoepithelial and alveolar cells. When injected orthotopically at low-density, the resulting tumors express estrogen and progesterone receptors. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL15887
43 Samples
Download data: PAIR
Series
Accession:
GSE61138
ID:
200061138
6.

Mouse mammary epithelial and stromal cells: Hormone Treated vs. Vehicle Control

(Submitter supplied) Transcriptional profiling of different mouse mammary cellular compartments (basal, luminal and stromal) under define hormone treatments: estrogen, progesterone, estrogen plus progesterone and the vehicle control. Goal was to determine the effect of ovarian hormones on mammary cellular compartment gene expression.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
40 Samples
Download data: TXT
Series
Accession:
GSE59558
ID:
200059558
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