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Zfp101 zinc finger protein 101 [ Mus musculus (house mouse) ]

Gene ID: 22643, updated on 9-Dec-2024

Summary

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Official Symbol
Zfp101provided by MGI
Official Full Name
zinc finger protein 101provided by MGI
Primary source
MGI:MGI:107547
See related
Ensembl:ENSMUSG00000055240 AllianceGenome:MGI:107547
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; heart; hemolymphoid system gland; and liver. Orthologous to human ZNF124 (zinc finger protein 124). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in CNS E11.5 (RPKM 7.9), limb E14.5 (RPKM 6.4) and 12 other tissues See more
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Genomic context

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See Zfp101 in Genome Data Viewer
Location:
17 B1; 17 17.98 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33599148..33613593, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (33380174..33394637, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 955B Neighboring gene zinc finger protein 422, pseudogene Neighboring gene zinc finger protein 81 Neighboring gene STARR-positive B cell enhancer mm9_chr17:33495732-33496033 Neighboring gene actin-like 9 Neighboring gene NFIL3 like basic leucine zipper

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel cDNA isolated from the mouse eye lens encoding a protein with zinc fingers and a KRAB domain. Brady JP, et al. DNA Seq, 1995. PMID 8777319
  2. Human MD2 deficiency-an inborn error of immunity with pleiotropic features. Li Y, et al. J Allergy Clin Immunol, 2023 Mar. PMID 36462957
  3. Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5. Abe K, et al. Mamm Genome, 2004 Apr. PMID 15112104
  4. Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. Bulfone A, et al. J Neurosci, 2005 Aug 17. PMID 16107646, Free PMC Article
  5. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Human MD2 deficiency-an inborn error of immunity with pleiotropic features.
    Title: Human MD2 deficiency-an inborn error of immunity with pleiotropic features.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 101

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001414008.1 → NP_001400937.1  zinc finger protein 101 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CT030734

  2. NM_001414009.1 → NP_001400938.1  zinc finger protein 101 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CT030734

  3. NM_001414010.1 → NP_001400939.1  zinc finger protein 101 isoform 3

    Status: VALIDATED

    Source sequence(s)
    CT030734

  4. NM_001414011.1 → NP_001400940.1  zinc finger protein 101 isoform 3

    Status: VALIDATED

    Source sequence(s)
    CT030734

  5. NM_001414012.1 → NP_001400941.1  zinc finger protein 101 isoform 3

    Status: VALIDATED

    Source sequence(s)
    CT030734

  6. NM_009542.3 → NP_033568.2  zinc finger protein 101 isoform 1

    See identical proteins and their annotated locations for NP_033568.2

    Status: VALIDATED

    Source sequence(s)
    CT030734
    Consensus CDS
    CCDS37565.1
    UniProtKB/TrEMBL
    Q8BP18
    Related
    ENSMUSP00000132508.3, ENSMUST00000167107.10
    Conserved Domains (6) summary
    smart00349
    Location:10 → 50
    KRAB; krueppel associated box
    COG5048
    Location:190 → 612
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:388 → 408
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:10 → 49
    KRAB; KRAB box
    pfam06798
    Location:32 → 80
    PrkA; PrkA serine protein kinase C-terminal domain
    pfam13465
    Location:428 → 453
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    33599148..33613593 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011246418.4 → XP_011244720.1  zinc finger protein 101 isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:187 → 609
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:385 → 405
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:6 → 46
    KRAB; KRAB box
Nucleotide Protein Strain
Heading Accession and Version

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