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cdc27 cell division cycle 27 [ Danio rerio (zebrafish) ]

Gene ID: 30450, updated on 19-Jun-2024

Summary

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Official Symbol
cdc27provided by ZNC
Official Full Name
cell division cycle 27provided by ZNC
Primary source
ZFIN:ZDB-GENE-990706-2
See related
Ensembl:ENSDARG00000056258 AllianceGenome:ZFIN:ZDB-GENE-990706-2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fb54g06; wu:fc88c12
Summary
Predicted to be involved in cell division; cellular protein metabolic process; and regulation of mitotic sister chromatid separation. Predicted to be part of anaphase-promoting complex. Predicted to be active in cytoplasm. Orthologous to human CDC27 (cell division cycle 27). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See cdc27 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
19
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (22036074..22054823)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (21905532..21924921)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107988034 Neighboring gene uncharacterized LOC101882289 Neighboring gene KAT8 regulatory NSL complex subunit 1b Neighboring gene microtubule-associated protein tau b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zebrafish stat3 is expressed in restricted tissues during embryogenesis and stat1 rescues cytokine signaling in a STAT1-deficient human cell line. Oates AC, et al. Dev Dyn, 1999 Aug. PMID 10417824
  2. Radiographic analysis of zebrafish skeletal defects. Fisher S, et al. Dev Biol, 2003 Dec 1. PMID 14623232
  3. Tissue factor pathway inhibitor-2: a novel gene involved in zebrafish central nervous system development. Zhang Y, et al. Dev Biol, 2013 Sep 1. PMID 23796905
  4. Rapid identification and isolation of zebrafish cDNA clones. Gong Z, et al. Gene, 1997 Nov 12. PMID 9409775
  5. A genetic linkage map for zebrafish: comparative analysis and localization of genes and expressed sequences. Gates MA, et al. Genome Res, 1999 Apr. PMID 10207156

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Functional and Genetic Analyses Unveil the Implication of CDC27 in Hemifacial Microsomia.
    Title: Functional and Genetic Analyses Unveil the Implication of CDC27 in Hemifacial Microsomia.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in anaphase-promoting complex-dependent catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell division IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in metaphase/anaphase transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of anaphase-promoting complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cell division cycle protein 27 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201449.1 → NP_958857.1  cell division cycle protein 27 homolog

    See identical proteins and their annotated locations for NP_958857.1

    Status: PROVISIONAL

    Source sequence(s)
    BC049466
    UniProtKB/TrEMBL
    Q7ZWD5
    Conserved Domains (4) summary
    COG0457
    Location:463 → 724
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:529 → 557
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:597 → 629
    TPR_1; Tetratricopeptide repeat
    pfam12895
    Location:17 → 92
    ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    22036074..22054823
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005171566.4 → XP_005171623.1  cell division cycle protein 27 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8M2BIV7, F1Q5X3
    Related
    ENSDARP00000113979.1, ENSDART00000132190.3
    Conserved Domains (4) summary
    COG0457
    Location:487 → 767
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:572 → 600
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:640 → 672
    TPR_1; Tetratricopeptide repeat
    pfam12895
    Location:17 → 92
    ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3
Nucleotide Protein Strain
Heading Accession and Version

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