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FPV_gp6 Small T antigen [ Finch polyomavirus ]

Gene ID: 5130558, updated on 18-Aug-2023

Summary

Gene symbol
FPV_gp6
Gene description
Small T antigen
Locus tag
FPV_gp6
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Finch polyomavirus (nat-host: Eurasian bullfinch (Pyrrhula pyrrhula griseiventris))
Lineage
Viruses; dsDNA viruses, no RNA stage; Polyomaviridae
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Genomic context

Sequence:
NC_007923.1 (4778..5278, complement)

NC_007923.1Genomic Context describing neighboring genes Neighboring gene putative ORF-X Neighboring gene putative VP2 Neighboring gene putative VP3 Neighboring gene Major capsid protein VP1 Neighboring gene large T antigen

General protein information

Preferred Names
Small T antigen
YP_529835.1
  • small T-antigen; promotes the efficient replication of genomic DNA; binds to and negativley regulates the function of protein phosphotase (PP2A) thereby accelerating the progression to S-phase; the small T-antigen shares a region in common with the large T-antigen known as the J-domain; the J-domain is required for multiple processes including assembly, viral genomic DNA replication and transcription; The polyomaviruses are non-enveloped dsDNA viruses; the viral genome is organized into two divergent transcriptional units known as early and late regions; mRNAs from the early region encode the viral small and large t-antigens; the small T antigen and large T antigen are expressed upon entry into the host nucleus early in the viral lifecycle; the small T antigen is not essential for replication in all cell lines

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007923.1 Reference assembly

    Range
    4778..5278 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_529835.1 putative small t antigen [Finch polyomavirus]

    See identical proteins and their annotated locations for YP_529835.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0A1E2T1, A0A2I6RKA7, Q20HX5
    Conserved Domains (1) summary
    PHA03102
    Location:1166
    PHA03102; Small T antigen; Reviewed