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TDRD1 tudor domain containing 1 [ Homo sapiens (human) ]

Gene ID: 56165, updated on 27-Nov-2024

Summary

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Official Symbol
TDRD1provided by HGNC
Official Full Name
tudor domain containing 1provided by HGNC
Primary source
HGNC:HGNC:11712
See related
Ensembl:ENSG00000095627 MIM:605796; AllianceGenome:HGNC:11712
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT41.1
Summary
This gene encodes a protein containing a tudor domain that is thought to function in the suppression of transposable elements during spermatogenesis. The related protein in mouse forms a complex with piRNAs and Piwi proteins to promote methylation and silencing of target sequences. This gene was observed to be upregulated by ETS transcription factor ERG in prostate tumors. [provided by RefSeq, Sep 2018]
Expression
Biased expression in testis (RPKM 8.5) and prostate (RPKM 0.6) See more
Orthologs
mouse all
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Genomic context

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See TDRD1 in Genome Data Viewer
Location:
10q25.3
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (114174874..114232666)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (115068498..115126291)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (115939046..115992425)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene UBE2V1 pseudogene 5 Neighboring gene coiled-coil domain containing 186 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:115933644-115934172 Neighboring gene microRNA 2110 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:115998924-115999632 Neighboring gene MPRA-validated peak1096 silencer Neighboring gene aurora kinase A pseudogene 2 Neighboring gene von Willebrand factor A domain containing 2 Neighboring gene MPRA-validated peak1097 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:116036689-116037189 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:116037297-116037798 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:116045355-116045966 Neighboring gene actin filament associated protein 1 like 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2843 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:116079781-116080980 Neighboring gene uncharacterized LOC105378494

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. The cancer testis antigen TDRD1 regulates prostate cancer proliferation by associating with the snRNP biogenesis machinery. Kim H, et al. Oncogene, 2023 Jun. PMID 37041411
  2. Association of a TDRD1 variant with spermatogenic failure susceptibility in the Han Chinese. Zhu XB, et al. J Assist Reprod Genet, 2016 Aug. PMID 27233649, Free PMC Article
  3. The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker. Xiao L, et al. Prostate, 2016 Oct. PMID 27272765
  4. The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors. Mathioudakis N, et al. RNA, 2012 Nov. PMID 22996915, Free PMC Article
  5. Identification of TDRD1 as a direct target gene of ERG in primary prostate cancer. Boormans JL, et al. Int J Cancer, 2013 Jul 15. PMID 23319146

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The cancer testis antigen TDRD1 regulates prostate cancer proliferation by associating with the snRNP biogenesis machinery.
    Title: The cancer testis antigen TDRD1 regulates prostate cancer proliferation by associating with the snRNP biogenesis machinery.
  2. Prospective assessment of two-gene urinary test with multiparametric magnetic resonance imaging of the prostate for men undergoing primary prostate biopsy.
    Title: Prospective assessment of two-gene urinary test with multiparametric magnetic resonance imaging of the prostate for men undergoing primary prostate biopsy.
  3. Mutational alterations of TDRD 1, 4 and 9 genes in colorectal cancers.
    Title: Mutational alterations of TDRD 1, 4 and 9 genes in colorectal cancers.
  4. Here we evaluate gene and protein expression levels of four key TDRDs (TDRD1, TDRD5, TDRD9 and TDRD12) in testicular biopsy samples obtained from men with obstructive azoospermia (OA, n = 29), as controls, and various types of non-obstructive azoospermia containing hypospermatogenesis (HP, 28), maturation arrest (MA, n = 30), and Sertoli cell-only syndrome (SCOS, n = 32) as cases.
    Title: Testicular expression of TDRD1, TDRD5, TDRD9 and TDRD12 in azoospermia.
  5. TDRD1 protein is expressed in the majority of human prostate tumors, but not in normal prostate tissue.
    Title: The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker.
  6. the involvement of TDRD1 genetic polymorphisms in piRNA processing genes in the risk of spermatogenic impairment in a Han Chinese population
    Title: Association of a TDRD1 variant with spermatogenic failure susceptibility in the Han Chinese.
  7. ERG induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG rearrangement-positive prostate cancer.
    Title: ERG induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG rearrangement-positive prostate cancer.
  8. TDRD1 is the first identified upregulated direct ERG target gene that is strongly associated with ERG overexpression in primary prostate cancer
    Title: Identification of TDRD1 as a direct target gene of ERG in primary prostate cancer.
  9. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.
    Title: Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
  10. Observational study of gene-disease association. (HuGE Navigator)
    Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ21082

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in P granule organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in germ cell development ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in piRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in piRNA processing ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in spermatogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spermatogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in transposable element silencing by piRNA-mediated DNA methylation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in P granule IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in P granule ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in chromatoid body IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in pi-body ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in synapse IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tudor domain-containing protein 1
Names
cancer/testis antigen 41.1
testicular tissue protein Li 193

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001365891.2 → NP_001352820.1  tudor domain-containing protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022023, BX648664
    Conserved Domains (2) summary
    pfam00567
    Location:712 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger

  2. NM_001385363.1 → NP_001372292.1  tudor domain-containing protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC022023
    Consensus CDS
    CCDS7588.1
    UniProtKB/TrEMBL
    A0A140VJW6
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1059
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

  3. NM_001385364.2 → NP_001372293.1  tudor domain-containing protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC022023
    Consensus CDS
    CCDS91352.1
    UniProtKB/Swiss-Prot
    A6NEN3, A6NMN2, B3KVI4, B4E2L5, D3DRC2, Q4G0Y8, Q6P518, Q9BXT4, Q9H7B3
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1059
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

  4. NM_001385365.1 → NP_001372294.1  tudor domain-containing protein 1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC022023
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1059
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

  5. NM_001385366.1 → NP_001372295.1  tudor domain-containing protein 1 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC022023
    Conserved Domains (5) summary
    pfam00567
    Location:658 → 775
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:887 → 1002
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cl02573
    Location:517 → 553
    Tudor_SF; Tudor domain superfamily

  6. NM_001385367.1 → NP_001372296.1  tudor domain-containing protein 1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC022023
    Consensus CDS
    CCDS91353.1
    UniProtKB/TrEMBL
    H9KV63
    Related
    ENSP00000358288.1, ENST00000369282.5
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1058
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

  7. NM_001385368.1 → NP_001372297.1  tudor domain-containing protein 1 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC022023
    Consensus CDS
    CCDS91354.1
    UniProtKB/TrEMBL
    H9KV62
    Related
    ENSP00000358286.1, ENST00000369280.1
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1058
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

  8. NM_001385369.1 → NP_001372298.1  tudor domain-containing protein 1 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC022023
    Consensus CDS
    CCDS91354.1
    UniProtKB/TrEMBL
    H9KV62
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1058
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

  9. NM_001385370.1 → NP_001372299.1  tudor domain-containing protein 1 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC022023
    Conserved Domains (5) summary
    pfam00567
    Location:658 → 726
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:830 → 945
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cl02573
    Location:517 → 553
    Tudor_SF; Tudor domain superfamily

  10. NM_001385371.1 → NP_001372300.1  tudor domain-containing protein 1 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC022023
    Conserved Domains (5) summary
    pfam00567
    Location:667 → 784
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20409
    Location:469 → 550
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:896 → 1010
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cl02573
    Location:268 → 348
    Tudor_SF; Tudor domain superfamily

  11. NM_001385372.1 → NP_001372301.1  tudor domain-containing protein 1 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC022023
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1058
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

  12. NM_001395205.1 → NP_001382134.1  tudor domain-containing protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC022023
    Consensus CDS
    CCDS91352.1
    UniProtKB/Swiss-Prot
    A6NEN3, A6NMN2, B3KVI4, B4E2L5, D3DRC2, Q4G0Y8, Q6P518, Q9BXT4, Q9H7B3
    Related
    ENSP00000511878.1, ENST00000695399.1
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1059
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

  13. NM_198795.2 → NP_942090.1  tudor domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_942090.1

    Status: REVIEWED

    Source sequence(s)
    AC022023, AK122916, BC035010, BQ882979, BX648664, CB136029
    Consensus CDS
    CCDS7588.1
    UniProtKB/TrEMBL
    A0A140VJW6
    Related
    ENSP00000251864.2, ENST00000251864.7
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1059
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    114174874..114232666
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011539962.2 → XP_011538264.1  tudor domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011538264.1

    UniProtKB/TrEMBL
    A0A140VJW6
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1059
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

  2. XM_011539964.3 → XP_011538266.1  tudor domain-containing protein 1 isoform X3

    Conserved Domains (3) summary
    cd04508
    Location:709 → 756
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    pfam00567
    Location:655 → 775
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger

  3. XM_047425489.1 → XP_047281445.1  tudor domain-containing protein 1 isoform X6

  4. XM_017016414.3 → XP_016871903.1  tudor domain-containing protein 1 isoform X2

  5. XM_047425488.1 → XP_047281444.1  tudor domain-containing protein 1 isoform X5

  6. XM_047425487.1 → XP_047281443.1  tudor domain-containing protein 1 isoform X4

  7. XM_047425491.1 → XP_047281447.1  tudor domain-containing protein 1 isoform X7

  8. XM_047425486.1 → XP_047281442.1  tudor domain-containing protein 1 isoform X3

  9. XM_047425490.1 → XP_047281446.1  tudor domain-containing protein 1 isoform X6

  10. XM_047425492.1 → XP_047281448.1  tudor domain-containing protein 1 isoform X7

  11. XM_011539959.3 → XP_011538261.1  tudor domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011538261.1

    UniProtKB/TrEMBL
    A0A140VJW6
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1059
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

  12. XM_011539960.3 → XP_011538262.1  tudor domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011538262.1

    UniProtKB/TrEMBL
    A0A140VJW6
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1059
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

  13. XM_011539961.3 → XP_011538263.1  tudor domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011538263.1

    UniProtKB/TrEMBL
    A0A140VJW6
    Conserved Domains (5) summary
    pfam00567
    Location:715 → 832
    TUDOR; Tudor domain
    pfam01753
    Location:170 → 206
    zf-MYND; MYND finger
    cd20408
    Location:268 → 396
    Tudor_TDRD1_rpt1; first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20409
    Location:517 → 598
    Tudor_TDRD1_rpt2; second Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins
    cd20411
    Location:944 → 1059
    Tudor_TDRD1_rpt4; fourth Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    115068498..115126291
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054366308.1 → XP_054222283.1  tudor domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A140VJW6

  2. XM_054366310.1 → XP_054222285.1  tudor domain-containing protein 1 isoform X3

  3. XM_054366314.1 → XP_054222289.1  tudor domain-containing protein 1 isoform X6

  4. XM_054366309.1 → XP_054222284.1  tudor domain-containing protein 1 isoform X2

  5. XM_054366313.1 → XP_054222288.1  tudor domain-containing protein 1 isoform X5

  6. XM_054366312.1 → XP_054222287.1  tudor domain-containing protein 1 isoform X4

  7. XM_054366316.1 → XP_054222291.1  tudor domain-containing protein 1 isoform X7

  8. XM_054366311.1 → XP_054222286.1  tudor domain-containing protein 1 isoform X3

  9. XM_054366315.1 → XP_054222290.1  tudor domain-containing protein 1 isoform X6

  10. XM_054366317.1 → XP_054222292.1  tudor domain-containing protein 1 isoform X7

  11. XM_054366305.1 → XP_054222280.1  tudor domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A140VJW6

  12. XM_054366306.1 → XP_054222281.1  tudor domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A140VJW6

  13. XM_054366307.1 → XP_054222282.1  tudor domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A140VJW6

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_031278.1: Suppressed sequence

    Description
    NM_031278.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9BXT4.2 GenPept UniProtKB/Swiss-Prot:Q9BXT4

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