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Prr36 proline rich 36 [ Mus musculus (house mouse) ]

Gene ID: 73072, updated on 9-Dec-2024

Summary

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Official Symbol
Prr36provided by MGI
Official Full Name
proline rich 36provided by MGI
Primary source
MGI:MGI:3605626
See related
Ensembl:ENSMUSG00000064125 AllianceGenome:MGI:3605626
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Is expressed in cerebral cortex intermediate zone and genitourinary system. Orthologous to human PRR36 (proline rich 36). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in whole brain E14.5 (RPKM 13.5), CNS E14 (RPKM 12.7) and 7 other tissues See more
Orthologs
human all
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Genomic context

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See Prr36 in Genome Data Viewer
Location:
8 A1.1; 8 1.98 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (4259478..4267530, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (4209478..4217530, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene CD209g antigen Neighboring gene STARR-seq mESC enhancer starr_20606 Neighboring gene STARR-seq mESC enhancer starr_20608 Neighboring gene RIKEN cDNA 4932443L11 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:4162949-4163058 Neighboring gene STARR-positive B cell enhancer ABC_E355 Neighboring gene ecotropic viral integration site 5 like Neighboring gene STARR-seq mESC enhancer starr_20610 Neighboring gene leucine rich repeat containing 8 family, member E Neighboring gene mitogen-activated protein kinase kinase 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Li J, et al. Nat Neurosci, 2017 Aug. PMID 28671696, Free PMC Article
  2. KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility. Gu J, et al. Cell Death Differ, 2023 Jul. PMID 37142655, Free PMC Article
  3. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
  4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
proline-rich protein 36

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207203.2 → NP_997086.2  proline-rich protein 36

    See identical proteins and their annotated locations for NP_997086.2

    Status: VALIDATED

    Source sequence(s)
    BC068157, CA326920
    Consensus CDS
    CCDS52473.1
    UniProtKB/TrEMBL
    E9PV26, Q6NVE5
    Related
    ENSMUSP00000133114.3, ENSMUST00000168386.9
    Conserved Domains (2) summary
    PHA03247
    Location:434 → 842
    PHA03247; large tegument protein UL36; Provisional
    pfam15363
    Location:1054 → 1098
    DUF4596; Domain of unknown function (DUF4596)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    4259478..4267530 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030243795.1 → XP_030099655.1  proline-rich protein 36 isoform X2

    UniProtKB/TrEMBL
    E9PV26, Q6NVE5
    Conserved Domains (2) summary
    PHA03247
    Location:434 → 842
    PHA03247; large tegument protein UL36; Provisional
    pfam15363
    Location:1054 → 1098
    DUF4596; Domain of unknown function (DUF4596)

  2. XM_011242087.3 → XP_011240389.1  proline-rich protein 36 isoform X2

    See identical proteins and their annotated locations for XP_011240389.1

    UniProtKB/TrEMBL
    E9PV26, Q6NVE5
    Conserved Domains (2) summary
    PHA03247
    Location:434 → 842
    PHA03247; large tegument protein UL36; Provisional
    pfam15363
    Location:1054 → 1098
    DUF4596; Domain of unknown function (DUF4596)

  3. XM_017312982.2 → XP_017168471.1  proline-rich protein 36 isoform X3

    UniProtKB/TrEMBL
    Q6NVE5
    Conserved Domains (3) summary
    PHA03247
    Location:382 → 790
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:10 → 261
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam15363
    Location:1002 → 1046
    DUF4596; Domain of unknown function (DUF4596)

  4. XM_030243796.2 → XP_030099656.1  proline-rich protein 36 isoform X2

    UniProtKB/TrEMBL
    E9PV26, Q6NVE5
    Conserved Domains (2) summary
    PHA03247
    Location:434 → 842
    PHA03247; large tegument protein UL36; Provisional
    pfam15363
    Location:1054 → 1098
    DUF4596; Domain of unknown function (DUF4596)

  5. XM_030243799.2 → XP_030099659.1  proline-rich protein 36 isoform X3

    UniProtKB/TrEMBL
    Q6NVE5
    Conserved Domains (3) summary
    PHA03247
    Location:382 → 790
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:10 → 261
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam15363
    Location:1002 → 1046
    DUF4596; Domain of unknown function (DUF4596)

  6. XM_006508912.5 → XP_006508975.1  proline-rich protein 36 isoform X2

    See identical proteins and their annotated locations for XP_006508975.1

    UniProtKB/TrEMBL
    E9PV26, Q6NVE5
    Conserved Domains (2) summary
    PHA03247
    Location:434 → 842
    PHA03247; large tegument protein UL36; Provisional
    pfam15363
    Location:1054 → 1098
    DUF4596; Domain of unknown function (DUF4596)

  7. XM_036154315.1 → XP_036010208.1  proline-rich protein 36 isoform X3

    UniProtKB/TrEMBL
    Q6NVE5
    Conserved Domains (3) summary
    PHA03247
    Location:382 → 790
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:10 → 261
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam15363
    Location:1002 → 1046
    DUF4596; Domain of unknown function (DUF4596)

  8. XM_030243798.2 → XP_030099658.1  proline-rich protein 36 isoform X3

    UniProtKB/TrEMBL
    Q6NVE5
    Conserved Domains (3) summary
    PHA03247
    Location:382 → 790
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:10 → 261
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam15363
    Location:1002 → 1046
    DUF4596; Domain of unknown function (DUF4596)

  9. XM_006508911.5 → XP_006508974.1  proline-rich protein 36 isoform X2

    See identical proteins and their annotated locations for XP_006508974.1

    UniProtKB/TrEMBL
    E9PV26, Q6NVE5
    Conserved Domains (2) summary
    PHA03247
    Location:434 → 842
    PHA03247; large tegument protein UL36; Provisional
    pfam15363
    Location:1054 → 1098
    DUF4596; Domain of unknown function (DUF4596)

  10. XM_006508914.5 → XP_006508977.1  proline-rich protein 36 isoform X3

    UniProtKB/TrEMBL
    Q6NVE5
    Conserved Domains (3) summary
    PHA03247
    Location:382 → 790
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:10 → 261
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam15363
    Location:1002 → 1046
    DUF4596; Domain of unknown function (DUF4596)

  11. XM_030243797.2 → XP_030099657.1  proline-rich protein 36 isoform X3

    UniProtKB/TrEMBL
    Q6NVE5
    Conserved Domains (3) summary
    PHA03247
    Location:382 → 790
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:10 → 261
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam15363
    Location:1002 → 1046
    DUF4596; Domain of unknown function (DUF4596)

  12. XM_017312981.3 → XP_017168470.1  proline-rich protein 36 isoform X2

    UniProtKB/TrEMBL
    E9PV26, Q6NVE5
    Conserved Domains (2) summary
    PHA03247
    Location:434 → 842
    PHA03247; large tegument protein UL36; Provisional
    pfam15363
    Location:1054 → 1098
    DUF4596; Domain of unknown function (DUF4596)

  13. XM_017312980.3 → XP_017168469.1  proline-rich protein 36 isoform X1

    UniProtKB/TrEMBL
    Q6NVE5
    Conserved Domains (2) summary
    PHA03247
    Location:456 → 864
    PHA03247; large tegument protein UL36; Provisional
    pfam15363
    Location:1076 → 1120
    DUF4596; Domain of unknown function (DUF4596)

  14. XM_006508913.4 → XP_006508976.1  proline-rich protein 36 isoform X2

    See identical proteins and their annotated locations for XP_006508976.1

    UniProtKB/TrEMBL
    E9PV26, Q6NVE5
    Conserved Domains (2) summary
    PHA03247
    Location:434 → 842
    PHA03247; large tegument protein UL36; Provisional
    pfam15363
    Location:1054 → 1098
    DUF4596; Domain of unknown function (DUF4596)
Nucleotide Protein Strain
Heading Accession and Version

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