U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gngt2b guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b [ Danio rerio (zebrafish) ]

Gene ID: 797361, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
gngt2bprovided by ZNC
Official Full Name
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-091020-4
See related
Ensembl:ENSDARG00000103543 AllianceGenome:ZFIN:ZDB-GENE-091020-4
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. Is expressed in pineal complex; retina; and retinal cone cell. Orthologous to human GNGT2 (G protein subunit gamma transducin 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See gngt2b in Genome Data Viewer
Location:
chromosome: 12
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (3249054..3252263, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (3420165..3423374, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496786 Neighboring gene si:ch1073-13h15.3 Neighboring gene transmembrane protein 101 Neighboring gene leucine-rich repeat-containing protein 70 Neighboring gene LSM12 homolog b

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Transducin duplicates in the zebrafish retina and pineal complex: differential specialisation after the teleost tetraploidisation. Lagman D, et al. PLoS One, 2015. PMID 25806532, Free PMC Article
  2. Prenylation-deficient G protein gamma subunits disrupt GPCR signaling in the zebrafish. Mulligan T, et al. Cell Signal, 2010 Feb. PMID 19786091, Free PMC Article
  3. Partitioning of gene expression among zebrafish photoreceptor subtypes. Ogawa Y, et al. Sci Rep, 2021 Aug 30. PMID 34462505, Free PMC Article
  4. Expansion of transducin subunit gene families in early vertebrate tetraploidizations. Lagman D, et al. Genomics, 2012 Oct. PMID 22814267
  5. Transcription factors involved in retinogenesis are co-opted by the circadian clock following photoreceptor differentiation. Laranjeiro R, et al. Development, 2014 Jul. PMID 24924194, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G-protein beta-subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables G-protein beta-subunit binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of heterotrimeric G-protein complex IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2b

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204332.1 → NP_001191261.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2b

    Status: VALIDATED

    Source sequence(s)
    EH447731, EH448553, EH451547
    UniProtKB/TrEMBL
    A0A8M1NYL7, E7F1F5
    Related
    ENSDARP00000141283.1, ENSDART00000170632.2
    Conserved Domains (1) summary
    smart00224
    Location:8 → 69
    GGL; G protein gamma subunit-like motifs

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    3249054..3252263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.