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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029226.1 RefSeqGene
- Range
-
5159..138552
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001278669.2 → NP_001265598.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform F
See identical proteins and their annotated locations for NP_001265598.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) encodes the longest isoform (F).
- Source sequence(s)
-
EU887559, EU887563, U80917
- Consensus CDS
-
CCDS62467.1
- UniProtKB/Swiss-Prot
- B5B2M4, B5B2M5, B5B2M6, B5B2M7, B5B2M8, B5B2M9, B5B2N1, O95644, Q12865, Q15793, Q2M1S3
- Related
- ENSP00000389377.2, ENST00000427363.7
- Conserved Domains (2) summary
-
- cd07881
Location:416 → 590
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cl15674
Location:595 → 695
- IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
-
NM_001278670.2 → NP_001265599.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform G
See identical proteins and their annotated locations for NP_001265599.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) lacks an in-frame exon in the 3' coding region, compared to variant 6. The encoded isoform (G) lacks an internal segment in the C-terminal region, compared to isoform F.
- Source sequence(s)
-
EU887561, EU887563, U80917
- Consensus CDS
-
CCDS62468.1
- UniProtKB/TrEMBL
-
A8K9C6
- Related
- ENSP00000442435.1, ENST00000542384.5
- Conserved Domains (2) summary
-
- cd07881
Location:416 → 590
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cl15674
Location:595 → 695
- IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
-
NM_001278672.2 → NP_001265601.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform H
See identical proteins and their annotated locations for NP_001265601.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) has an alternate 5' terminal exon, which results in a different 5' UTR and 5' coding region, and lacks an in-frame exon in the 3' coding region, compared to variant 6. The encoded isoform (H) is shorter; it has a distinct N-terminus and lacks an internal segment in the C-terminal region, compared to isoform F.
- Source sequence(s)
-
EU887562, EU887563, HY039825
- Consensus CDS
-
CCDS62469.1
- UniProtKB/TrEMBL
-
A8K9C6
- Related
- ENSP00000466489.1, ENST00000586434.1
- Conserved Domains (2) summary
-
- cd07881
Location:403 → 577
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cl15674
Location:582 → 682
- IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
-
NM_001278673.2 → NP_001265602.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform J
Status: REVIEWED
- Description
- Transcript Variant: This variant (10) has an alternate 5' terminal exon and lacks an internal exon in the 5' region, which results in a downstream translation start codon, compared to variant 6. The encoded isoform (J) is shorter at the N-terminus, compared to isoform F.
- Source sequence(s)
-
AK293760, EU887559, EU887563, HY039825
- Consensus CDS
-
CCDS62471.1
- UniProtKB/TrEMBL
- B4DER8, F5H4S8
- Related
- ENSP00000439992.1, ENST00000545796.5
- Conserved Domains (2) summary
-
- cl08275
Location:1 → 118
- RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)
- cl15674
Location:123 → 223
- IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
-
NM_001278675.2 → NP_001265604.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform I
See identical proteins and their annotated locations for NP_001265604.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (9) has multiple differences, compared to variant 6. These differences result in distinct 5' and 3' UTRs and 5' and 3' terminal coding regions, compared to variant 6. The encoded isoform (I) is shorter and has distinct N- and C-termini, compared to isoform F.
- Source sequence(s)
-
AA621079, AC018445, EU887566, HY039825
- Consensus CDS
-
CCDS62470.1
- UniProtKB/TrEMBL
-
A8K9C6
- Related
- ENSP00000467181.1, ENST00000592223.5
- Conserved Domains (2) summary
-
- cd07881
Location:403 → 577
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cl15674
Location:582 → 682
- IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
-
NM_006162.5 → NP_006153.2 nuclear factor of activated T-cells, cytoplasmic 1 isoform B
See identical proteins and their annotated locations for NP_006153.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 6. The encoded isoform (B) is truncated at the C-terminus, compared to isoform F.
- Source sequence(s)
-
EU887563, U80917
- Consensus CDS
-
CCDS12015.1
- UniProtKB/TrEMBL
-
A8K9C6
- Related
- ENSP00000253506.5, ENST00000253506.9
- Conserved Domains (2) summary
-
- cd07881
Location:416 → 590
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cl15674
Location:595 → 695
- IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
-
NM_172387.3 → NP_765975.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform C
See identical proteins and their annotated locations for NP_765975.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) has an alternate 5' terminal exon, which results in a different 5' UTR and 5' coding region, compared to variant 6. The encoded isoform (C) is shorter and has a distinct N-terminus, compared to isoform F.
- Source sequence(s)
-
EU887560, EU887563, HY039825, U80918
- Consensus CDS
-
CCDS32850.1
- UniProtKB/Swiss-Prot
-
O95644
- Related
- ENSP00000327850.3, ENST00000329101.8
- Conserved Domains (2) summary
-
- cd07881
Location:403 → 577
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cl15674
Location:582 → 682
- IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
-
NM_172388.3 → NP_765976.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform D
See identical proteins and their annotated locations for NP_765976.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an internal exon in the 5' region, which results in a downstream translation start codon, and has an alternate splice site in the 3' coding region, compared to variant 6. The encoded isoform (D) is shorter at both the N- and C- termini, compared to isoform F.
- Source sequence(s)
-
AW014910, EU887563, U80919
- Consensus CDS
-
CCDS12016.1
- UniProtKB/Swiss-Prot
-
O95644
- Related
- ENSP00000380892.2, ENST00000397790.6
- Conserved Domains (2) summary
-
- cl08275
Location:1 → 118
- RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)
- cl15674
Location:123 → 223
- IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
-
NM_172389.3 → NP_765977.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform E
See identical proteins and their annotated locations for NP_765977.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) has an alternate 5' terminal exon, which results in a different 5' UTR and 5' coding region, and uses an alternate splice site in the 3' coding region, compared to variant 6. The encoded isoform (E, also known as C.b) is shorter; it has a distinct N-terminus and is truncated at the C-terminus, compared to isoform F.
- Source sequence(s)
-
EU887563, HY039825, U59736
- Consensus CDS
-
CCDS59327.1
- UniProtKB/TrEMBL
-
A8K9C6
- Related
- ENSP00000316553.5, ENST00000318065.9
- Conserved Domains (2) summary
-
- cd07881
Location:403 → 577
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cl15674
Location:582 → 682
- IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
-
NM_172390.3 → NP_765978.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform A
See identical proteins and their annotated locations for NP_765978.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) lacks two exons and its transcription extends past a splice site that is used in variant 6, which results in a novel 3' coding region and 3' UTR, compared to variant 6. The encoded isoform (A) is shorter and has a distinct C-terminus, compared to isoform F.
- Source sequence(s)
-
AA621079, AC018445, AK292641, EU887565
- Consensus CDS
-
CCDS59326.1
- UniProtKB/TrEMBL
-
A8K9C6
- Related
- ENSP00000466194.1, ENST00000591814.5
- Conserved Domains (3) summary
-
- cd07881
Location:416 → 590
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cl15674
Location:595 → 695
- IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
- cl26464
Location:53 → 292
- Atrophin-1; Atrophin-1 family
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000018.10 Reference GRCh38.p14 Primary Assembly
- Range
-
79395930..79529323
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017025783.3 → XP_016881272.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform X1
- UniProtKB/TrEMBL
-
A8K9C6
-
XM_047437538.1 → XP_047293494.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform X2
- UniProtKB/TrEMBL
-
A8K9C6
Alternate T2T-CHM13v2.0
Genomic
-
NC_060942.1 Alternate T2T-CHM13v2.0
- Range
-
79649928..79782943
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054318662.1 → XP_054174637.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform X1
- UniProtKB/TrEMBL
-
A8K9C6
-
XM_054318663.1 → XP_054174638.1 nuclear factor of activated T-cells, cytoplasmic 1 isoform X2
- UniProtKB/TrEMBL
-
A8K9C6