cholesterol transporter ABCA5
|
ABCA5
|
interacts with |
PubMed
|
ATP-binding cassette sub-family D member 3 isoform a
|
ABCD3
|
interacts with |
PubMed
|
3-ketoacyl-CoA thiolase, mitochondrial
|
ACAA2
|
enhances |
PubMed
|
acetyl-CoA acetyltransferase, mitochondrial isoform b precursor
|
ACAT1
|
downregulates |
PubMed
|
Golgi resident protein GCP60
|
ACBD3
|
downregulates |
PubMed
|
acyl-CoA-binding domain-containing protein 5 isoform 1
|
ACBD5
|
interacts with |
PubMed
|
long-chain-fatty-acid--CoA ligase 4 isoform 1
|
ACSL4
|
upregulates |
PubMed
|
actin, aortic smooth muscle isoform 1
|
ACTA2
|
downregulates |
PubMed
|
actin, cytoplasmic 1
|
ACTB
|
downregulates |
PubMed
|
beta-actin-like protein 2
|
ACTBL2
|
downregulates |
PubMed
|
actin, cytoplasmic 2
|
ACTG1
|
downregulates |
PubMed
|
|
ACTG1
|
enhances polymerization of |
PubMed
|
alpha-actinin-1 isoform a
|
ACTN1
|
upregulates |
PubMed
|
alpha-actinin-4 isoform 1
|
ACTN4
|
upregulates |
PubMed
|
alkyldihydroxyacetonephosphate synthase, peroxisomal precursor
|
AGPS
|
interacts with |
PubMed
|
aryl hydrocarbon receptor
|
AHR
|
regulated by |
PubMed
|
|
AHR
|
cooperates with |
PubMed
|
single-stranded DNA cytosine deaminase isoform 1
|
AICDA
|
co-localizes with |
PubMed
|
|
AICDA
|
inhibits |
PubMed
|
|
AICDA
|
interacts with |
PubMed
|
apoptosis-inducing factor 1, mitochondrial isoform AIF precursor
|
AIFM1
|
downregulates |
PubMed
|
|
AIFM1
|
interacts with |
PubMed
|
adenylate kinase 2, mitochondrial isoform a
|
AK2
|
downregulates |
PubMed
|
RAC-alpha serine/threonine-protein kinase
|
AKT1
|
involves |
PubMed
|
|
AKT1
|
involves |
PubMed
|
|
AKT1
|
decreases phosphorylation of |
PubMed
|
|
AKT1
|
inhibits |
PubMed
|
RAC-beta serine/threonine-protein kinase isoform 1
|
AKT2
|
regulated by |
PubMed
|
|
AKT2
|
involves |
PubMed
|
|
AKT2
|
involves |
PubMed
|
|
AKT2
|
decreases phosphorylation of |
PubMed
|
|
AKT2
|
inhibits |
PubMed
|
RAC-gamma serine/threonine-protein kinase isoform 1
|
AKT3
|
regulated by |
PubMed
|
|
AKT3
|
inhibits |
PubMed
|
fructose-bisphosphate aldolase A isoform 1
|
ALDOA
|
downregulates |
PubMed
|
fructose-bisphosphate aldolase C
|
ALDOC
|
downregulates |
PubMed
|
ankyrin repeat and KH domain-containing protein 1 isoform 1
|
ANKHD1
|
interacts with |
PubMed
|
ankyrin repeat domain-containing protein 13A
|
ANKRD13A
|
interacts with |
PubMed
|
ankyrin repeat domain-containing protein 17 isoform a
|
ANKRD17
|
interacts with |
PubMed
|
anillin isoform 1
|
ANLN
|
upregulates |
PubMed
|
annexin A3
|
ANXA3
|
downregulates |
PubMed
|
DNA dC->dU-editing enzyme APOBEC-3A isoform b
|
APOBEC3A
|
upregulates |
PubMed
|
DNA dC->dU-editing enzyme APOBEC-3C
|
APOBEC3C
|
upregulates |
PubMed
|
DNA dC->dU-editing enzyme APOBEC-3G isoform 1
|
APOBEC3G
|
induces ubiquitination of |
PubMed
|
|
APOBEC3G
|
degrades |
PubMed
|
|
APOBEC3G
|
upregulates |
PubMed
|
apolipoprotein E isoform b precursor
|
APOE
|
upregulates |
PubMed
|
arginase-2, mitochondrial precursor
|
ARG2
|
downregulates |
PubMed
|
rho GDP-dissociation inhibitor 1 isoform a
|
ARHGDIA
|
upregulates |
PubMed
|
rho GDP-dissociation inhibitor 2
|
ARHGDIB
|
modulates |
PubMed
|
acid ceramidase isoform b
|
ASAH1
|
upregulates |
PubMed
|
cyclic AMP-dependent transcription factor ATF-1 isoform c
|
ATF1
|
activates |
PubMed
|
|
ATF1
|
activates |
PubMed
|
serine-protein kinase ATM isoform a
|
ATM
|
activates |
PubMed
|
ATP synthase subunit alpha, mitochondrial isoform a precursor
|
ATP5F1A
|
downregulates |
PubMed
|
ATP synthase subunit beta, mitochondrial precursor
|
ATP5F1B
|
downregulates |
PubMed
|
ATP synthase subunit delta, mitochondrial precursor
|
ATP5F1D
|
downregulates |
PubMed
|
ATP synthase F(0) complex subunit B1, mitochondrial precursor
|
ATP5PB
|
downregulates |
PubMed
|
V-type proton ATPase subunit B, brain isoform
|
ATP6V1B2
|
upregulates |
PubMed
|
serine/threonine-protein kinase ATR isoform 1
|
ATR
|
activates |
PubMed
|
|
ATR
|
activates |
PubMed
|
|
ATR
|
interacts with |
PubMed
|
|
ATR
|
activates |
PubMed
|
|
ATR
|
activates |
PubMed
|
|
ATR
|
interacts with |
PubMed
|
|
ATR
|
activates |
PubMed
|
|
ATR
|
interacts with |
PubMed
|
aurora kinase A isoform 1
|
AURKA
|
upregulates |
PubMed
|
aurora kinase B isoform 1
|
AURKB
|
upregulates |
PubMed
|
|
AURKB
|
downregulates |
PubMed
|
tyrosine-protein kinase receptor UFO isoform 3
|
AXL
|
upregulates |
PubMed
|
apoptosis regulator BAX isoform beta
|
BAX
|
dependent on |
PubMed
|
|
BAX
|
upregulates |
PubMed
|
|
BAX
|
mediated by |
PubMed
|
|
BAX
|
upregulates |
PubMed
|
|
BAX
|
downregulates |
PubMed
|
|
BAX
|
enhanced by |
PubMed
|
B-cell lymphoma/leukemia 11B isoform 2
|
BCL11B
|
inhibited by |
PubMed
|
apoptosis regulator Bcl-2 isoform alpha
|
BCL2
|
downregulates |
PubMed
|
|
BCL2
|
upregulates |
PubMed
|
|
BCL2
|
inhibited by |
PubMed
|
bcl-2-like protein 1 isoform Bcl-X(L)
|
BCL2L1
|
interacts with |
PubMed
|
|
BCL2L1
|
downregulates |
PubMed
|
|
BCL2L1
|
relocalizes |
PubMed
|
|
BCL2L1
|
downregulates |
PubMed
|
BH3-interacting domain death agonist isoform 2
|
BID
|
dependent on |
PubMed
|
|
BID
|
induces cleavage of |
PubMed
|
|
BID
|
induces cleavage of |
PubMed
|
|
BID
|
upregulates |
PubMed
|
baculoviral IAP repeat-containing protein 2 isoform 1
|
BIRC2
|
inhibited by |
PubMed
|
baculoviral IAP repeat-containing protein 3
|
BIRC3
|
counteracted by |
PubMed
|
|
BIRC3
|
inhibited by |
PubMed
|
baculoviral IAP repeat-containing protein 5 isoform 1
|
BIRC5
|
upregulates |
PubMed
|
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
|
BNIP3
|
downregulates |
PubMed
|
|
BNIP3
|
upregulates |
PubMed
|
breast cancer type 1 susceptibility protein isoform 1
|
BRCA1
|
stimulates |
PubMed
|
|
BRCA1
|
induces phosphorylation of |
PubMed
|
|
BRCA1
|
relocalizes |
PubMed
|
bone marrow stromal antigen 2 precursor
|
BST2
|
downregulates |
PubMed
|
complement component 1 Q subcomponent-binding protein, mitochondrial precursor
|
C1QBP
|
downregulates |
PubMed
|
C3a anaphylatoxin chemotactic receptor
|
C3AR1
|
upregulates |
PubMed
|
C5a anaphylatoxin chemotactic receptor 1
|
C5AR1
|
upregulates |
PubMed
|
calreticulin precursor
|
CALR
|
upregulates |
PubMed
|
macrophage-capping protein isoform 1
|
CAPG
|
downregulates |
PubMed
|
F-actin-capping protein subunit alpha-1
|
CAPZA1
|
upregulates |
PubMed
|
caspase-1 isoform alpha precursor
|
CASP1
|
activates |
PubMed
|
caspase-3 isoform a preproprotein
|
CASP3
|
activates |
PubMed
|
|
CASP3
|
activates |
PubMed
|
|
CASP3
|
cooperates with |
PubMed
|
|
CASP3
|
regulated by |
PubMed
|
|
CASP3
|
activates |
PubMed
|
|
CASP3
|
induces cleavage of |
PubMed
|
|
CASP3
|
activates |
PubMed
|
|
CASP3
|
activates |
PubMed
|
|
CASP3
|
activates |
PubMed
|
|
CASP3
|
activates |
PubMed
|
|
CASP3
|
activates |
PubMed
|
caspase-6 isoform alpha precursor
|
CASP6
|
activates |
PubMed
|
|
CASP6
|
upregulates |
PubMed
|
caspase-7 isoform alpha precursor
|
CASP7
|
activates |
PubMed
|
|
CASP7
|
activates |
PubMed
|
|
CASP7
|
activates |
PubMed
|
|
CASP7
|
upregulates |
PubMed
|
caspase-8 isoform 1 precursor
|
CASP8
|
dependent on |
PubMed
|
|
CASP8
|
activates |
PubMed
|
|
CASP8
|
activates |
PubMed
|
CASP8-associated protein 2
|
CASP8AP2
|
upregulates |
PubMed
|
caspase-9 isoform alpha precursor
|
CASP9
|
activates |
PubMed
|
|
CASP9
|
activates |
PubMed
|
|
CASP9
|
activates |
PubMed
|
|
CASP9
|
activates |
PubMed
|
|
CASP9
|
activates |
PubMed
|
|
CASP9
|
activates |
PubMed
|
caveolin-1 isoform alpha
|
CAV1
|
mediated by |
PubMed
|
chromobox protein homolog 3 isoform a
|
CBX3
|
relocalizes |
PubMed
|
chromobox protein homolog 5
|
CBX5
|
relocalizes |
PubMed
|
|
CBX5
|
relocalizes |
PubMed
|
cell cycle and apoptosis regulator protein 2 isoform 1
|
CCAR2
|
downregulates |
PubMed
|
PAT complex subunit CCDC47 precursor
|
CCDC47
|
interacts with |
PubMed
|
C-C motif chemokine 1 precursor
|
CCL1
|
downregulates |
PubMed
|
C-C motif chemokine 2 precursor
|
CCL2
|
upregulates |
PubMed
|
C-C motif chemokine 20 isoform 2 precursor
|
CCL20
|
downregulates |
PubMed
|
C-C motif chemokine 23 isoform CKbeta8-1 precursor
|
CCL23
|
upregulates |
PubMed
|
C-C motif chemokine 26 precursor
|
CCL26
|
upregulates |
PubMed
|
C-C motif chemokine 3 precursor
|
CCL3
|
downregulates |
PubMed
|
C-C motif chemokine 3-like 1 precursor
|
CCL3L3
|
upregulates |
PubMed
|
C-C motif chemokine 4 precursor
|
CCL4
|
downregulates |
PubMed
|
C-C motif chemokine 5 isoform 1 precursor
|
CCL5
|
upregulates |
PubMed
|
|
CCL5
|
upregulates |
PubMed
|
|
CCL5
|
upregulates |
PubMed
|
|
CCL5
|
regulates |
PubMed
|
C-C motif chemokine 8 precursor
|
CCL8
|
upregulates |
PubMed
|
G2/mitotic-specific cyclin-B1 isoform 1
|
CCNB1
|
upregulates |
PubMed
|
|
CCNB1
|
induces accumulation of |
PubMed
|
|
CCNB1
|
interacts with |
PubMed
|
|
CCNB1
|
interacts with |
PubMed
|
|
CCNB1
|
induces release of |
PubMed
|
|
CCNB1
|
inactivates |
PubMed
|
|
CCNB1
|
inhibits |
PubMed
|
|
CCNB1
|
inactivates |
PubMed
|
|
CCNB1
|
inactivates |
PubMed
|
|
CCNB1
|
inactivates |
PubMed
|
|
CCNB1
|
inactivates |
PubMed
|
G2/mitotic-specific cyclin-B2
|
CCNB2
|
inactivates |
PubMed
|
|
CCNB2
|
inhibits |
PubMed
|
|
CCNB2
|
inactivates |
PubMed
|
|
CCNB2
|
inactivates |
PubMed
|
|
CCNB2
|
inactivates |
PubMed
|
|
CCNB2
|
inactivates |
PubMed
|
G2/mitotic-specific cyclin-B3 isoform 3
|
CCNB3
|
inactivates |
PubMed
|
|
CCNB3
|
inhibits |
PubMed
|
|
CCNB3
|
inactivates |
PubMed
|
|
CCNB3
|
inactivates |
PubMed
|
|
CCNB3
|
inactivates |
PubMed
|
|
CCNB3
|
inactivates |
PubMed
|
cyclin-H isoform 1
|
CCNH
|
inhibited by |
PubMed
|
|
CCNH
|
enhanced by |
PubMed
|
cyclin-T1 isoform a
|
CCNT1
|
binds |
PubMed
|
C-C chemokine receptor type 5
|
CCR5
|
interacts with |
PubMed
|
T-cell surface glycoprotein CD1a isoform 2
|
CD1A
|
upregulates |
PubMed
|
antigen-presenting glycoprotein CD1d isoform 2 precursor
|
CD1D
|
downregulates |
PubMed
|
T-cell-specific surface glycoprotein CD28 isoform 1 precursor
|
CD28
|
downregulates |
PubMed
|
myeloid cell surface antigen CD33 isoform 1 precursor
|
CD33
|
downregulates |
PubMed
|
T-cell surface glycoprotein CD3 epsilon chain precursor
|
CD3E
|
antagonizes |
PubMed
|
T-cell surface glycoprotein CD4 isoform 1 precursor
|
CD4
|
downregulates |
PubMed
|
|
CD4
|
downregulates |
PubMed
|
|
CD4
|
downregulates |
PubMed
|
tumor necrosis factor receptor superfamily member 5 isoform 1 precursor
|
CD40
|
downregulates |
PubMed
|
CD44 antigen isoform 1 precursor
|
CD44
|
upregulates |
PubMed
|
|
CD44
|
downregulates |
PubMed
|
early activation antigen CD69
|
CD69
|
activates |
PubMed
|
T-lymphocyte activation antigen CD80 precursor
|
CD80
|
downregulates |
PubMed
|
|
CD80
|
downregulates |
PubMed
|
CD83 antigen isoform a precursor
|
CD83
|
downregulates |
PubMed
|
|
CD83
|
downregulates |
PubMed
|
T-lymphocyte activation antigen CD86 isoform 1 precursor
|
CD86
|
downregulates |
PubMed
|
|
CD86
|
downregulates |
PubMed
|
M-phase inducer phosphatase 1 isoform a
|
CDC25A
|
relocalizes |
PubMed
|
|
CDC25A
|
relocalizes |
PubMed
|
M-phase inducer phosphatase 2 isoform 1
|
CDC25B
|
relocalizes |
PubMed
|
|
CDC25B
|
relocalizes |
PubMed
|
M-phase inducer phosphatase 3 isoform a
|
CDC25C
|
relocalizes |
PubMed
|
|
CDC25C
|
relocalizes |
PubMed
|
|
CDC25C
|
interacts with |
PubMed
|
|
CDC25C
|
binds |
PubMed
|
|
CDC25C
|
binds |
PubMed
|
|
CDC25C
|
complexes with |
PubMed
|
|
CDC25C
|
induces release of |
PubMed
|
|
CDC25C
|
inactivates |
PubMed
|
|
CDC25C
|
inactivates |
PubMed
|
|
CDC25C
|
inactivates |
PubMed
|
cadherin-1 isoform 1 preproprotein
|
CDH1
|
upregulates |
PubMed
|
cyclin-dependent kinase 1 isoform 1
|
CDK1
|
inactivates |
PubMed
|
|
CDK1
|
interacts with |
PubMed
|
|
CDK1
|
interacts with |
PubMed
|
|
CDK1
|
inactivates |
PubMed
|
|
CDK1
|
inhibits |
PubMed
|
|
CDK1
|
activates |
PubMed
|
|
CDK1
|
inactivates |
PubMed
|
|
CDK1
|
inactivates |
PubMed
|
|
CDK1
|
inactivates |
PubMed
|
cyclin-dependent kinase 7 isoform 1
|
CDK7
|
inhibited by |
PubMed
|
|
CDK7
|
enhanced by |
PubMed
|
cyclin-dependent kinase 9
|
CDK9
|
interacts with |
PubMed
|
cyclin-dependent kinase inhibitor 1 isoform 1
|
CDKN1A
|
activates |
PubMed
|
|
CDKN1A
|
upregulates |
PubMed
|
|
CDKN1A
|
interacts with |
PubMed
|
|
CDKN1A
|
upregulates |
PubMed
|
|
CDKN1A
|
activates |
PubMed
|
DNA replication factor Cdt1
|
CDT1
|
cooperates with |
PubMed
|
CCAAT/enhancer-binding protein beta isoform a
|
CEBPB
|
cooperates with |
PubMed
|
|
CEBPB
|
cooperates with |
PubMed
|
|
CEBPB
|
activates |
PubMed
|
|
CEBPB
|
activates |
PubMed
|
CCAAT/enhancer-binding protein delta
|
CEBPD
|
involves |
PubMed
|
|
CEBPD
|
involves |
PubMed
|
histone H3-like centromeric protein A isoform a
|
CENPA
|
co-localizes with |
PubMed
|
centromere protein F
|
CENPF
|
upregulates |
PubMed
|
centromere protein H
|
CENPH
|
co-localizes with |
PubMed
|
centrosomal protein of 170 kDa isoform alpha
|
CEP170
|
interacts with |
PubMed
|
centrin-2
|
CETN2
|
induces accumulation of |
PubMed
|
serine/threonine-protein kinase Chk1 isoform 1
|
CHEK1
|
activates |
PubMed
|
|
CHEK1
|
induces phosphorylation of |
PubMed
|
|
CHEK1
|
induces phosphorylation of |
PubMed
|
serine/threonine-protein kinase Chk2 isoform a
|
CHEK2
|
induces phosphorylation of |
PubMed
|
|
CHEK2
|
induces phosphorylation of |
PubMed
|
chitinase-3-like protein 1 precursor
|
CHI3L1
|
upregulates |
PubMed
|
inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1
|
CHUK
|
requires |
PubMed
|
cold-inducible RNA-binding protein isoform 1
|
CIRBP
|
upregulates |
PubMed
|
chloride intracellular channel protein 1
|
CLIC1
|
downregulates |
PubMed
|
clathrin light chain A isoform a
|
CLTA
|
mediated by |
PubMed
|
clathrin light chain B isoform a
|
CLTB
|
mediated by |
PubMed
|
clathrin heavy chain 1 isoform 1
|
CLTC
|
upregulates |
PubMed
|
|
CLTC
|
mediated by |
PubMed
|
catechol O-methyltransferase isoform MB-COMT
|
COMT
|
interacts with |
PubMed
|
COP9 signalosome complex subunit 2 isoform 1
|
COPS2
|
interacts with |
PubMed
|
COP9 signalosome complex subunit 3 isoform 1
|
COPS3
|
interacts with |
PubMed
|
COP9 signalosome complex subunit 4 isoform 1
|
COPS4
|
interacts with |
PubMed
|
COP9 signalosome complex subunit 5
|
COPS5
|
interacts with |
PubMed
|
COP9 signalosome complex subunit 6
|
COPS6
|
interacts with |
PubMed
|
|
COPS6
|
interacts with |
PubMed
|
|
COPS6
|
interacts with |
PubMed
|
|
COPS6
|
interacts with |
PubMed
|
|
COPS6
|
binds |
PubMed
|
COP9 signalosome complex subunit 8 isoform 1
|
COPS8
|
interacts with |
PubMed
|
cytochrome c oxidase subunit 4 isoform 1, mitochondrial isoform 1 precursor
|
COX4I1
|
co-localizes with |
PubMed
|
carnitine O-palmitoyltransferase 1, liver isoform isoform 1
|
CPT1A
|
enhances |
PubMed
|
carnitine O-palmitoyltransferase 1, muscle isoform isoform a
|
CPT1B
|
enhances |
PubMed
|
cyclic AMP-responsive element-binding protein 1 isoform A
|
CREB1
|
downregulates |
PubMed
|
CREB-binding protein isoform a
|
CREBBP
|
binds |
PubMed
|
cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor
|
CTLA4
|
upregulates |
PubMed
|
lysosomal protective protein isoform a precursor
|
CTSA
|
upregulates |
PubMed
|
cathepsin B isoform 1 preproprotein
|
CTSB
|
upregulates |
PubMed
|
cathepsin D preproprotein
|
CTSD
|
upregulates |
PubMed
|
pro-cathepsin H isoform a preproprotein
|
CTSH
|
upregulates |
PubMed
|
cathepsin Z preproprotein
|
CTSZ
|
upregulates |
PubMed
|
cullin-4A isoform 2
|
CUL4A
|
induces |
PubMed
|
|
CUL4A
|
induces complex with |
PubMed
|
|
CUL4A
|
cooperates with |
PubMed
|
|
CUL4A
|
complexes with |
PubMed
|
|
CUL4A
|
interacts with |
PubMed
|
|
CUL4A
|
interacts with |
PubMed
|
|
CUL4A
|
interacts with |
PubMed
|
|
CUL4A
|
interacts with |
PubMed
|
|
CUL4A
|
interacts with |
PubMed
|
|
CUL4A
|
co-localizes with |
PubMed
|
|
CUL4A
|
complexes with |
PubMed
|
|
CUL4A
|
interacts with |
PubMed
|
|
CUL4A
|
binds |
PubMed
|
cullin-4B isoform 1
|
CUL4B
|
complexes with |
PubMed
|
|
CUL4B
|
interacts with |
PubMed
|
C-X-C motif chemokine 10 precursor
|
CXCL10
|
upregulates |
PubMed
|
C-X-C motif chemokine 11 isoform 2 precursor
|
CXCL11
|
upregulates |
PubMed
|
C-X-C motif chemokine 13 precursor
|
CXCL13
|
upregulates |
PubMed
|
interleukin-8 isoform 1 precursor
|
CXCL8
|
upregulates |
PubMed
|
|
CXCL8
|
downregulates |
PubMed
|
|
CXCL8
|
involves |
PubMed
|
|
CXCL8
|
involves |
PubMed
|
|
CXCL8
|
enhances |
PubMed
|
|
CXCL8
|
upregulates |
PubMed
|
|
CXCL8
|
upregulates |
PubMed
|
|
CXCL8
|
upregulates |
PubMed
|
|
CXCL8
|
enhances |
PubMed
|
|
CXCL8
|
involves |
PubMed
|
|
CXCL8
|
involves |
PubMed
|
|
CXCL8
|
involves |
PubMed
|
|
CXCL8
|
involves |
PubMed
|
|
CXCL8
|
regulates |
PubMed
|
cytochrome c1, heme protein, mitochondrial precursor
|
CYC1
|
downregulates |
PubMed
|
cytochrome c
|
CYCS
|
induces release of |
PubMed
|
|
CYCS
|
induces release of |
PubMed
|
cytoglobin
|
CYGB
|
downregulates |
PubMed
|
DDB1- and CUL4-associated factor 1 isoform 1
|
DCAF1
|
requires |
PubMed
|
|
DCAF1
|
cooperates with |
PubMed
|
|
DCAF1
|
binds |
PubMed
|
|
DCAF1
|
binds |
PubMed
|
|
DCAF1
|
requires |
PubMed
|
|
DCAF1
|
binds |
PubMed
|
|
DCAF1
|
recruits |
PubMed
|
|
DCAF1
|
complexes with |
PubMed
|
|
DCAF1
|
interacts with |
PubMed
|
|
DCAF1
|
recruits |
PubMed
|
|
DCAF1
|
complexes with |
PubMed
|
|
DCAF1
|
degrades |
PubMed
|
|
DCAF1
|
complexes with |
PubMed
|
|
DCAF1
|
interacts with |
PubMed
|
|
DCAF1
|
interacts with |
PubMed
|
|
DCAF1
|
interacts with |
PubMed
|
|
DCAF1
|
cooperates with |
PubMed
|
|
DCAF1
|
co-localizes with |
PubMed
|
|
DCAF1
|
binds |
PubMed
|
|
DCAF1
|
interacts with |
PubMed
|
|
DCAF1
|
interacts with |
PubMed
|
|
DCAF1
|
cooperates with |
PubMed
|
|
DCAF1
|
interacts with |
PubMed
|
|
DCAF1
|
binds |
PubMed
|
|
DCAF1
|
binds |
PubMed
|
|
DCAF1
|
cooperates with |
PubMed
|
|
DCAF1
|
cooperates with |
PubMed
|
|
DCAF1
|
co-localizes with |
PubMed
|
|
DCAF1
|
binds |
PubMed
|
|
DCAF1
|
interacts with |
PubMed
|
|
DCAF1
|
binds |
PubMed
|
|
DCAF1
|
binds |
PubMed
|
DDB1- and CUL4-associated factor 11 isoform 1
|
DCAF11
|
interacts with |
PubMed
|
DDB1- and CUL4-associated factor 8
|
DCAF8
|
interacts with |
PubMed
|
dynactin subunit 1 isoform 3
|
DCTN1
|
relocalizes |
PubMed
|
DET1- and DDB1-associated protein 1
|
DDA1
|
interacts with |
PubMed
|
DNA damage-binding protein 1
|
DDB1
|
enhances |
PubMed
|
|
DDB1
|
binds |
PubMed
|
|
DDB1
|
cooperates with |
PubMed
|
|
DDB1
|
degrades |
PubMed
|
|
DDB1
|
recruits |
PubMed
|
|
DDB1
|
complexes with |
PubMed
|
|
DDB1
|
complexes with |
PubMed
|
|
DDB1
|
interacts with |
PubMed
|
|
DDB1
|
induces complex with |
PubMed
|
|
DDB1
|
interacts with |
PubMed
|
|
DDB1
|
interacts with |
PubMed
|
|
DDB1
|
interacts with |
PubMed
|
|
DDB1
|
interacts with |
PubMed
|
|
DDB1
|
co-localizes with |
PubMed
|
|
DDB1
|
interacts with |
PubMed
|
|
DDB1
|
binds |
PubMed
|
|
DDB1
|
cooperates with |
PubMed
|
|
DDB1
|
stabilized by |
PubMed
|
|
DDB1
|
cooperates with |
PubMed
|
|
DDB1
|
inhibits |
PubMed
|
|
DDB1
|
interacts with |
PubMed
|
DNA damage-binding protein 2 isoform WT
|
DDB2
|
inhibits |
PubMed
|
probable ATP-dependent RNA helicase DDX20
|
DDX20
|
interacts with |
PubMed
|
probable ATP-dependent RNA helicase DDX5 isoform a
|
DDX5
|
upregulates |
PubMed
|
probable ATP-dependent RNA helicase DDX60 isoform 1
|
DDX60
|
upregulates |
PubMed
|
diacylglycerol kinase kappa
|
DGKK
|
upregulates |
PubMed
|
diablo IAP-binding mitochondrial protein isoform 1 precursor
|
DIABLO
|
induces release of |
PubMed
|
endoribonuclease Dicer isoform 1
|
DICER1
|
downregulates |
PubMed
|
|
DICER1
|
complexes with |
PubMed
|
dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform 1 precursor
|
DLST
|
upregulates |
PubMed
|
dnaJ homolog subfamily B member 2 isoform b
|
DNAJB2
|
downregulates |
PubMed
|
dnaJ homolog subfamily B member 6 isoform a
|
DNAJB6
|
facilitated by |
PubMed
|
dynamin-1-like protein isoform 3
|
DNM1L
|
downregulates |
PubMed
|
|
DNM1L
|
relocalizes |
PubMed
|
protein C-mannosyl-transferase DPY19L1 isoform 2
|
DPY19L1
|
interacts with |
PubMed
|
protein C-mannosyl-transferase DPY19L3
|
DPY19L3
|
interacts with |
PubMed
|
dual oxidase 2 isoform 1 precursor
|
DUOX2
|
downregulates |
PubMed
|
dual specificity protein phosphatase 1
|
DUSP1
|
downregulates |
PubMed
|
cytoplasmic dynein 1 heavy chain 1
|
DYNC1H1
|
relocalizes |
PubMed
|
|
DYNC1H1
|
interacts with |
PubMed
|
|
DYNC1H1
|
interacts with |
PubMed
|
cytoplasmic dynein 1 intermediate chain 2 isoform 1
|
DYNC1I2
|
interacts with |
PubMed
|
cytoplasmic dynein 1 light intermediate chain 1 isoform 1
|
DYNC1LI1
|
interacts with |
PubMed
|
dynein light chain Tctex-type 1 isoform 1
|
DYNLT1
|
interacts with |
PubMed
|
dysferlin isoform 8
|
DYSF
|
upregulates |
PubMed
|
interleukin-27 subunit beta precursor
|
EBI3
|
downregulates |
PubMed
|
enoyl-CoA delta isomerase 1, mitochondrial isoform 1 precursor
|
ECI1
|
downregulates |
PubMed
|
early endosome antigen 1
|
EEA1
|
upregulates |
PubMed
|
elongation factor 2
|
EEF2
|
inhibited by |
PubMed
|
eukaryotic translation initiation factor 4E isoform 1
|
EIF4E
|
downregulates |
PubMed
|
eukaryotic translation initiation factor 4E-binding protein 1
|
EIF4EBP1
|
downregulates |
PubMed
|
crossover junction endonuclease EME1 isoform 2
|
EME1
|
interacts with |
PubMed
|
|
EME1
|
induces phosphorylation of |
PubMed
|
|
EME1
|
complexes with |
PubMed
|
histone acetyltransferase p300 isoform 1
|
EP300
|
interacts with |
PubMed
|
|
EP300
|
recruits |
PubMed
|
|
EP300
|
activates |
PubMed
|
|
EP300
|
activates |
PubMed
|
|
EP300
|
enhanced by |
PubMed
|
|
EP300
|
binds |
PubMed
|
|
EP300
|
binds |
PubMed
|
DNA excision repair protein ERCC-1 isoform 2
|
ERCC1
|
complexes with |
PubMed
|
DNA repair endonuclease XPF
|
ERCC4
|
complexes with |
PubMed
|
electron transfer flavoprotein subunit alpha, mitochondrial isoform a
|
ETFA
|
downregulates |
PubMed
|
electron transfer flavoprotein subunit beta isoform 1
|
ETFB
|
downregulates |
PubMed
|
persulfide dioxygenase ETHE1, mitochondrial isoform 1
|
ETHE1
|
downregulates |
PubMed
|
RNA-binding protein EWS isoform 1
|
EWSR1
|
upregulates |
PubMed
|
ezrin
|
EZR
|
downregulates |
PubMed
|
|
EZR
|
upregulates |
PubMed
|
proteinase-activated receptor 1 isoform 2
|
F2R
|
blocks |
PubMed
|
Fanconi anemia group D2 protein isoform a
|
FANCD2
|
increases |
PubMed
|
tumor necrosis factor receptor superfamily member 6 isoform 1 precursor
|
FAS
|
cooperates with |
PubMed
|
high affinity immunoglobulin epsilon receptor subunit gamma precursor
|
FCER1G
|
upregulates |
PubMed
|
low affinity immunoglobulin gamma Fc region receptor II-c precursor
|
FCGR2C
|
upregulates |
PubMed
|
low affinity immunoglobulin gamma Fc region receptor III-A isoform a
|
FCGR3A
|
antagonizes |
PubMed
|
fumarate hydratase, mitochondrial
|
FH
|
upregulates |
PubMed
|
filamin-A isoform 2
|
FLNA
|
upregulates |
PubMed
|
filamin-B isoform 1
|
FLNB
|
upregulates |
PubMed
|
protein c-Fos
|
FOS
|
regulated by |
PubMed
|
|
FOS
|
activates |
PubMed
|
forkhead box protein M1 isoform 2
|
FOXM1
|
downregulates |
PubMed
|
forkhead box protein O3 isoform 1
|
FOXO3
|
inhibits |
PubMed
|
|
FOXO3
|
inhibits |
PubMed
|
ferritin heavy chain
|
FTH1
|
upregulates |
PubMed
|
ferritin light chain
|
FTL
|
downregulates |
PubMed
|
ras GTPase-activating protein-binding protein 2 isoform a
|
G3BP2
|
upregulates |
PubMed
|
glucose-6-phosphate 1-dehydrogenase isoform a
|
G6PD
|
upregulates |
PubMed
|
growth arrest and DNA damage-inducible protein GADD45 alpha isoform 1
|
GADD45A
|
upregulates |
PubMed
|
glyceraldehyde-3-phosphate dehydrogenase isoform 1
|
GAPDH
|
downregulates |
PubMed
|
|
GAPDH
|
downregulates |
PubMed
|
guanylate-binding protein 5 isoform 1
|
GBP5
|
antagonizes |
PubMed
|
gem-associated protein 2 isoform alpha
|
GEMIN2
|
interacts with |
PubMed
|
gem-associated protein 4
|
GEMIN4
|
interacts with |
PubMed
|
gem-associated protein 6
|
GEMIN6
|
interacts with |
PubMed
|
gem-associated protein 7
|
GEMIN7
|
interacts with |
PubMed
|
glial fibrillary acidic protein isoform 1
|
GFAP
|
interacts with |
PubMed
|
ADP-ribosylation factor-binding protein GGA1 isoform 1
|
GGA1
|
co-localizes with |
PubMed
|
ADP-ribosylation factor-binding protein GGA2
|
GGA2
|
co-localizes with |
PubMed
|
ADP-ribosylation factor-binding protein GGA3 isoform short
|
GGA3
|
co-localizes with |
PubMed
|
glutamate dehydrogenase 2, mitochondrial precursor
|
GLUD2
|
downregulates |
PubMed
|
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform 1
|
GNB1
|
upregulates |
PubMed
|
N-acetylglucosamine-6-sulfatase precursor
|
GNS
|
upregulates |
PubMed
|
Golgi phosphoprotein 3
|
GOLPH3
|
interacts with |
PubMed
|
glucose-6-phosphate isomerase isoform 2
|
GPI
|
downregulates |
PubMed
|
COP9 signalosome complex subunit 1 isoform 2
|
GPS1
|
interacts with |
PubMed
|
epididymal secretory glutathione peroxidase isoform 1 precursor
|
GPX5
|
upregulates |
PubMed
|
glycogen synthase kinase-3 beta isoform 1
|
GSK3B
|
downregulates |
PubMed
|
gelsolin isoform a precursor
|
GSN
|
upregulates |
PubMed
|
|
GSN
|
inhibited by |
PubMed
|
glutathione S-transferase kappa 1 isoform a
|
GSTK1
|
downregulates |
PubMed
|
glutathione S-transferase P
|
GSTP1
|
upregulates |
PubMed
|
transcription initiation factor IIB
|
GTF2B
|
binds |
PubMed
|
general transcription factor IIH subunit 1
|
GTF2H1
|
inhibited by |
PubMed
|
|
GTF2H1
|
enhanced by |
PubMed
|
histone H2AX
|
H2AX
|
interacts with |
PubMed
|
|
H2AX
|
induces phosphorylation of |
PubMed
|
|
H2AX
|
induces phosphorylation of |
PubMed
|
|
H2AX
|
activates |
PubMed
|
hydroxyacyl-coenzyme A dehydrogenase, mitochondrial isoform 2 precursor
|
HADH
|
enhances |
PubMed
|
trifunctional enzyme subunit alpha, mitochondrial precursor
|
HADHA
|
downregulates |
PubMed
|
histone acetyltransferase type B catalytic subunit
|
HAT1
|
complexes with |
PubMed
|
|
HAT1
|
interacts with |
PubMed
|
histone deacetylase 1
|
HDAC1
|
depletes |
PubMed
|
|
HDAC1
|
binds |
PubMed
|
|
HDAC1
|
depletes |
PubMed
|
|
HDAC1
|
cooperates with |
PubMed
|
histone deacetylase 2
|
HDAC2
|
depletes |
PubMed
|
|
HDAC2
|
cooperates with |
PubMed
|
histone deacetylase 3 isoform 2
|
HDAC3
|
depletes |
PubMed
|
|
HDAC3
|
binds |
PubMed
|
|
HDAC3
|
depletes |
PubMed
|
histone deacetylase 8 isoform 2
|
HDAC8
|
depletes |
PubMed
|
hepatoma-derived growth factor isoform a
|
HDGF
|
downregulates |
PubMed
|
hepatoma-derived growth factor-related protein 2 isoform 2
|
HDGFL2
|
interacts with |
PubMed
|
E3 ISG15--protein ligase HERC5
|
HERC5
|
upregulates |
PubMed
|
hypoxia-inducible factor 1-alpha isoform 1
|
HIF1A
|
regulates |
PubMed
|
|
HIF1A
|
upregulates |
PubMed
|
hexokinase-1 isoform HKI
|
HK1
|
induces accumulation of |
PubMed
|
|
HK1
|
upregulates |
PubMed
|
|
HK1
|
upregulates |
PubMed
|
hexokinase-2 isoform 1
|
HK2
|
upregulates |
PubMed
|
HLA class I histocompatibility antigen, A alpha chain isoform A*03:01:01:01 precursor
|
HLA-A
|
upregulates |
PubMed
|
major histocompatibility complex, class I, B precursor
|
HLA-B
|
interacts with |
PubMed
|
HLA class I histocompatibility antigen, C alpha chain precursor
|
HLA-C
|
interacts with |
PubMed
|
helicase-like transcription factor isoform 2
|
HLTF
|
downregulates |
PubMed
|
|
HLTF
|
binds |
PubMed
|
|
HLTF
|
recruits |
PubMed
|
|
HLTF
|
downregulates |
PubMed
|
|
HLTF
|
downregulates |
PubMed
|
heterogeneous nuclear ribonucleoproteins A2/B1 isoform A2
|
HNRNPA2B1
|
regulated by |
PubMed
|
heterogeneous nuclear ribonucleoprotein D0 isoform c
|
HNRNPD
|
downregulates |
PubMed
|
heterogeneous nuclear ribonucleoprotein F
|
HNRNPF
|
regulated by |
PubMed
|
heterogeneous nuclear ribonucleoprotein H isoform a
|
HNRNPH1
|
regulated by |
PubMed
|
heterogeneous nuclear ribonucleoprotein U isoform b
|
HNRNPU
|
modulated by |
PubMed
|
hypoxanthine-guanine phosphoribosyltransferase
|
HPRT1
|
downregulates |
PubMed
|
3-hydroxyacyl-CoA dehydrogenase type-2 isoform 1
|
HSD17B10
|
downregulates |
PubMed
|
peroxisomal multifunctional enzyme type 2 isoform 2
|
HSD17B4
|
upregulates |
PubMed
|
heat shock factor protein 1
|
HSF1
|
inhibits |
PubMed
|
|
HSF1
|
upregulates |
PubMed
|
heat shock protein HSP 90-beta isoform a
|
HSP90AB1
|
upregulates |
PubMed
|
heat shock 70 kDa protein 1A
|
HSPA1A
|
interacts with |
PubMed
|
|
HSPA1A
|
binds |
PubMed
|
|
HSPA1A
|
inhibited by |
PubMed
|
|
HSPA1A
|
inhibited by |
PubMed
|
|
HSPA1A
|
competes with |
PubMed
|
heat shock 70 kDa protein 1B
|
HSPA1B
|
interacts with |
PubMed
|
|
HSPA1B
|
competes with |
PubMed
|
heat shock-related 70 kDa protein 2
|
HSPA2
|
upregulates |
PubMed
|
|
HSPA2
|
interacts with |
PubMed
|
|
HSPA2
|
competes with |
PubMed
|
heat shock 70 kDa protein 4
|
HSPA4
|
interacts with |
PubMed
|
|
HSPA4
|
competes with |
PubMed
|
endoplasmic reticulum chaperone BiP precursor
|
HSPA5
|
upregulates |
PubMed
|
|
HSPA5
|
interacts with |
PubMed
|
|
HSPA5
|
upregulates |
PubMed
|
|
HSPA5
|
competes with |
PubMed
|
heat shock 70 kDa protein 6
|
HSPA6
|
interacts with |
PubMed
|
|
HSPA6
|
competes with |
PubMed
|
heat shock cognate 71 kDa protein isoform 1
|
HSPA8
|
interacts with |
PubMed
|
|
HSPA8
|
competes with |
PubMed
|
stress-70 protein, mitochondrial precursor
|
HSPA9
|
interacts with |
PubMed
|
|
HSPA9
|
competes with |
PubMed
|
heat shock protein beta-1
|
HSPB1
|
competes with |
PubMed
|
|
HSPB1
|
inhibited by |
PubMed
|
60 kDa heat shock protein, mitochondrial
|
HSPD1
|
downregulates |
PubMed
|
hypoxia up-regulated protein 1 isoform 1 precursor
|
HYOU1
|
upregulates |
PubMed
|
isocitrate dehydrogenase
|
IDH2
|
downregulates |
PubMed
|
indoleamine 2,3-dioxygenase 1
|
IDO1
|
downregulates |
PubMed
|
gamma-interferon-inducible protein 16 isoform 1
|
IFI16
|
antagonizes |
PubMed
|
interferon alpha-inducible protein 27, mitochondrial isoform 2
|
IFI27
|
upregulates |
PubMed
|
|
IFI27
|
upregulates |
PubMed
|
interferon-induced 35 kDa protein isoform 1
|
IFI35
|
upregulates |
PubMed
|
interferon-induced protein 44-like isoform 1
|
IFI44L
|
upregulates |
PubMed
|
|
IFI44L
|
upregulates |
PubMed
|
interferon alpha-inducible protein 6 isoform c precursor
|
IFI6
|
upregulates |
PubMed
|
interferon-induced helicase C domain-containing protein 1
|
IFIH1
|
upregulates |
PubMed
|
interferon-induced protein with tetratricopeptide repeats 1 isoform 1
|
IFIT1
|
antagonizes |
PubMed
|
|
IFIT1
|
upregulates |
PubMed
|
|
IFIT1
|
upregulates |
PubMed
|
interferon-induced protein with tetratricopeptide repeats 2
|
IFIT2
|
upregulates |
PubMed
|
|
IFIT2
|
upregulates |
PubMed
|
interferon-induced protein with tetratricopeptide repeats 3 isoform a
|
IFIT3
|
upregulates |
PubMed
|
interferon-induced transmembrane protein 1
|
IFITM1
|
interacts with |
PubMed
|
|
IFITM1
|
upregulates |
PubMed
|
|
IFITM1
|
interacts with |
PubMed
|
interferon-induced transmembrane protein 2
|
IFITM2
|
upregulates |
PubMed
|
|
IFITM2
|
interacts with |
PubMed
|
interferon-induced transmembrane protein 3
|
IFITM3
|
upregulates |
PubMed
|
|
IFITM3
|
interacts with |
PubMed
|
interferon alpha-1/13 precursor
|
IFNA1
|
abrogated by |
PubMed
|
|
IFNA1
|
inhibits |
PubMed
|
|
IFNA1
|
inhibits |
PubMed
|
|
IFNA1
|
upregulates |
PubMed
|
interferon alpha-10 precursor
|
IFNA10
|
inhibits |
PubMed
|
|
IFNA13
|
inhibits |
PubMed
|
interferon alpha-14 precursor
|
IFNA14
|
inhibits |
PubMed
|
interferon alpha-16 precursor
|
IFNA16
|
inhibits |
PubMed
|
interferon alpha-17 precursor
|
IFNA17
|
inhibits |
PubMed
|
interferon alpha-2 precursor
|
IFNA2
|
antagonizes |
PubMed
|
|
IFNA2
|
inhibits |
PubMed
|
interferon alpha-21 precursor
|
IFNA21
|
inhibits |
PubMed
|
interferon alpha-4 precursor
|
IFNA4
|
inhibits |
PubMed
|
interferon alpha-5 precursor
|
IFNA5
|
inhibits |
PubMed
|
interferon alpha-6 precursor
|
IFNA6
|
inhibits |
PubMed
|
interferon alpha-7 precursor
|
IFNA7
|
inhibits |
PubMed
|
interferon alpha-8 precursor
|
IFNA8
|
inhibits |
PubMed
|
interferon beta precursor
|
IFNB1
|
inhibits |
PubMed
|
interferon gamma precursor
|
IFNG
|
inhibits |
PubMed
|
|
IFNG
|
downregulates |
PubMed
|
|
IFNG
|
downregulates |
PubMed
|
|
IFNG
|
upregulates |
PubMed
|
inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1
|
IKBKB
|
requires |
PubMed
|
|
IKBKB
|
induces phosphorylation of |
PubMed
|
interleukin-10 isoform 1 precursor
|
IL10
|
upregulates |
PubMed
|
|
IL10
|
modulates |
PubMed
|
interleukin-12 subunit alpha isoform 1 precursor
|
IL12A
|
modulates |
PubMed
|
|
IL12A
|
downregulates |
PubMed
|
|
IL12A
|
downregulates |
PubMed
|
|
IL12A
|
downregulates |
PubMed
|
interleukin-12 subunit beta precursor
|
IL12B
|
downregulates |
PubMed
|
interleukin-1 alpha precursor
|
IL1A
|
upregulates |
PubMed
|
interleukin-1 beta proprotein
|
IL1B
|
activates |
PubMed
|
interleukin-2 precursor
|
IL2
|
downregulates |
PubMed
|
|
IL2
|
downregulates |
PubMed
|
interleukin-4 isoform 1 precursor
|
IL4
|
downregulates |
PubMed
|
interleukin-6 isoform 1 precursor
|
IL6
|
upregulates |
PubMed
|
|
IL6
|
upregulates |
PubMed
|
|
IL6
|
involves |
PubMed
|
|
IL6
|
involves |
PubMed
|
|
IL6
|
enhances |
PubMed
|
|
IL6
|
upregulates |
PubMed
|
|
IL6
|
upregulates |
PubMed
|
|
IL6
|
upregulates |
PubMed
|
|
IL6
|
enhances |
PubMed
|
|
IL6
|
involves |
PubMed
|
|
IL6
|
involves |
PubMed
|
|
IL6
|
involves |
PubMed
|
|
IL6
|
involves |
PubMed
|
|
IL6
|
downregulates |
PubMed
|
|
IL6
|
upregulates |
PubMed
|
|
IL6
|
upregulates |
PubMed
|
|
IL6
|
upregulates |
PubMed
|
interleukin enhancer-binding factor 3 isoform b
|
ILF3
|
downregulates |
PubMed
|
inner centromere protein isoform 2
|
INCENP
|
upregulates |
PubMed
|
|
INCENP
|
relocalizes |
PubMed
|
|
INCENP
|
downregulates |
PubMed
|
insulin preproprotein
|
INS
|
inhibits |
PubMed
|
|
INS
|
inhibits |
PubMed
|
|
INS
|
inhibits |
PubMed
|
importin-5
|
IPO5
|
interacts with |
PubMed
|
|
IPO5
|
regulates |
PubMed
|
importin-7
|
IPO7
|
imported by |
PubMed
|
interferon regulatory factor 3 isoform 1
|
IRF3
|
induces cleavage of |
PubMed
|
|
IRF3
|
inhibits |
PubMed
|
|
IRF3
|
degrades |
PubMed
|
interferon regulatory factor 7 isoform a
|
IRF7
|
upregulates |
PubMed
|
ubiquitin-like protein ISG15
|
ISG15
|
upregulates |
PubMed
|
|
ISG15
|
upregulates |
PubMed
|
interferon-stimulated gene 20 kDa protein isoform a
|
ISG20
|
upregulates |
PubMed
|
isochorismatase domain-containing protein 2 isoform 2
|
ISOC2
|
downregulates |
PubMed
|
integrin alpha-5 precursor
|
ITGA5
|
upregulates |
PubMed
|
integrin alpha-6 isoform b preproprotein
|
ITGA6
|
upregulates |
PubMed
|
integrin alpha-M isoform 2 precursor
|
ITGAM
|
upregulates |
PubMed
|
integrin alpha-X isoform 2 precursor
|
ITGAX
|
upregulates |
PubMed
|
integrin beta-1 isoform 1A precursor
|
ITGB1
|
upregulates |
PubMed
|
integrin beta-2 isoform 1 precursor
|
ITGB2
|
upregulates |
PubMed
|
transcription factor Jun
|
JUN
|
involves |
PubMed
|
|
JUN
|
involves |
PubMed
|
|
JUN
|
regulated by |
PubMed
|
|
JUN
|
activates |
PubMed
|
lysine--tRNA ligase isoform 2
|
KARS1
|
relocalizes |
PubMed
|
|
KARS1
|
inhibits |
PubMed
|
far upstream element-binding protein 2 isoform 1
|
KHSRP
|
upregulates |
PubMed
|
kinesin-like protein KIF22 isoform 1
|
KIF22
|
upregulates |
PubMed
|
kinesin-like protein KIF2C isoform 1
|
KIF2C
|
upregulates |
PubMed
|
kinesin-like protein KIFC1
|
KIFC1
|
upregulates |
PubMed
|
importin subunit alpha-5
|
KPNA1
|
binds |
PubMed
|
|
KPNA1
|
interacts with |
PubMed
|
|
KPNA1
|
binds |
PubMed
|
|
KPNA1
|
interacts with |
PubMed
|
|
KPNA1
|
imported by |
PubMed
|
|
KPNA1
|
interacts with |
PubMed
|
importin subunit alpha-1
|
KPNA2
|
binds |
PubMed
|
|
KPNA2
|
binds |
PubMed
|
|
KPNA2
|
binds |
PubMed
|
|
KPNA2
|
imported by |
PubMed
|
|
KPNA2
|
interacts with |
PubMed
|
|
KPNA2
|
interacts with |
PubMed
|
importin subunit alpha-3
|
KPNA4
|
binds |
PubMed
|
importin subunit beta-1 isoform 1
|
KPNB1
|
interacts with |
PubMed
|
|
KPNB1
|
regulates |
PubMed
|
lysosome-associated membrane glycoprotein 1 precursor
|
LAMP1
|
inhibits |
PubMed
|
|
LAMP1
|
abrogates |
PubMed
|
|
LAMP1
|
downregulates |
PubMed
|
lysosome-associated membrane glycoprotein 2 isoform C precursor
|
LAMP2
|
reduces |
PubMed
|
linker for activation of T-cells family member 2
|
LAT2
|
upregulates |
PubMed
|
mitochondrial proton/calcium exchanger protein precursor
|
LETM1
|
downregulates |
PubMed
|
galectin-3 isoform 2
|
LGALS3
|
upregulates |
PubMed
|
lamin isoform A
|
LMNA
|
downregulates |
PubMed
|
|
LMNA
|
co-localizes with |
PubMed
|
lamin-B1 isoform 1
|
LMNB1
|
downregulates |
PubMed
|
|
LMNB1
|
co-localizes with |
PubMed
|
lamin-B2
|
LMNB2
|
downregulates |
PubMed
|
|
LMNB2
|
co-localizes with |
PubMed
|
LIM domain only protein 7 isoform 3
|
LMO7
|
upregulates |
PubMed
|
dual specificity mitogen-activated protein kinase kinase 1 isoform 1
|
MAP2K1
|
cooperates with |
PubMed
|
dual specificity mitogen-activated protein kinase kinase 2
|
MAP2K2
|
cooperates with |
PubMed
|
|
MAP2K2
|
decreases phosphorylation of |
PubMed
|
|
MAP2K2
|
downregulates |
PubMed
|
dual specificity mitogen-activated protein kinase kinase 7 isoform 3
|
MAP2K7
|
induces phosphorylation of |
PubMed
|
|
MAP2K7
|
activates |
PubMed
|
mitogen-activated protein kinase kinase kinase 7 isoform A
|
MAP3K7
|
enhances |
PubMed
|
|
MAP3K7
|
activates |
PubMed
|
|
MAP3K7
|
interacts with |
PubMed
|
|
MAP3K7
|
induces phosphorylation of |
PubMed
|
|
MAP3K7
|
induces phosphorylation of |
PubMed
|
mitogen-activated protein kinase 1
|
MAPK1
|
activates |
PubMed
|
mitogen-activated protein kinase 11
|
MAPK11
|
involves |
PubMed
|
|
MAPK11
|
involves |
PubMed
|
mitogen-activated protein kinase 13
|
MAPK13
|
involves |
PubMed
|
|
MAPK13
|
regulated by |
PubMed
|
mitogen-activated protein kinase 14 isoform 1
|
MAPK14
|
cooperates with |
PubMed
|
|
MAPK14
|
cooperates with |
PubMed
|
mitogen-activated protein kinase 3 isoform 1
|
MAPK3
|
activates |
PubMed
|
mitogen-activated protein kinase 8 isoform alpha2
|
MAPK8
|
involves |
PubMed
|
|
MAPK8
|
involves |
PubMed
|
|
MAPK8
|
involves |
PubMed
|
|
MAPK8
|
activates |
PubMed
|
MAP kinase-activated protein kinase 2 isoform 1
|
MAPKAPK2
|
requires |
PubMed
|
microtubule-associated protein RP/EB family member 1
|
MAPRE1
|
relocalizes |
PubMed
|
|
MAPRE1
|
interacts with |
PubMed
|
macrophage receptor MARCO
|
MARCO
|
stimulates |
PubMed
|
matrin-3 isoform a
|
MATR3
|
upregulates |
PubMed
|
|
MATR3
|
interacts with |
PubMed
|
induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1
|
MCL1
|
interacts with |
PubMed
|
protein MCM10 homolog isoform 2
|
MCM10
|
depletes |
PubMed
|
|
MCM10
|
enhances |
PubMed
|
|
MCM10
|
degrades |
PubMed
|
DNA replication licensing factor MCM3 isoform 1
|
MCM3
|
downregulates |
PubMed
|
DNA replication licensing factor MCM5
|
MCM5
|
downregulates |
PubMed
|
DNA replication licensing factor MCM6
|
MCM6
|
downregulates |
PubMed
|
malate dehydrogenase, mitochondrial isoform 1 precursor
|
MDH2
|
downregulates |
PubMed
|
mitofusin-2
|
MFN2
|
downregulates |
PubMed
|
glutathione S-transferase 3, mitochondrial
|
MGST3
|
downregulates |
PubMed
|
macrophage migration inhibitory factor
|
MIF
|
upregulates |
PubMed
|
protein MIS12 homolog
|
MIS12
|
relocalizes |
PubMed
|
mitotic interactor and substrate of PLK1
|
MISP
|
upregulates |
PubMed
|
MAP kinase-interacting serine/threonine-protein kinase 2 isoform 1
|
MKNK2
|
downregulates |
PubMed
|
interstitial collagenase isoform 1 preproprotein
|
MMP1
|
downregulates |
PubMed
|
CDK-activating kinase assembly factor MAT1 isoform 1
|
MNAT1
|
inhibited by |
PubMed
|
|
MNAT1
|
enhanced by |
PubMed
|
mannosyl-oligosaccharide glucosidase isoform 1
|
MOGS
|
interacts with |
PubMed
|
moesin
|
MSN
|
downregulates |
PubMed
|
metallothionein-3
|
MT3
|
downregulates |
PubMed
|
metastasis-associated protein MTA2 isoform 1
|
MTA2
|
interacts with |
PubMed
|
mitochondrial carrier homolog 2 isoform 1
|
MTCH2
|
interacts with |
PubMed
|
protein LYRIC isoform 1
|
MTDH
|
upregulates |
PubMed
|
crossover junction endonuclease MUS81 isoform 2
|
MUS81
|
downregulates |
PubMed
|
|
MUS81
|
affects |
PubMed
|
|
MUS81
|
interacts with |
PubMed
|
|
MUS81
|
degrades |
PubMed
|
|
MUS81
|
induces ubiquitination of |
PubMed
|
|
MUS81
|
interacts with |
PubMed
|
|
MUS81
|
complexes with |
PubMed
|
interferon-induced GTP-binding protein Mx1 isoform a
|
MX1
|
upregulates |
PubMed
|
|
MX1
|
upregulates |
PubMed
|
|
MX1
|
downregulates |
PubMed
|
interferon-induced GTP-binding protein Mx2
|
MX2
|
upregulates |
PubMed
|
|
MX2
|
upregulates |
PubMed
|
myeloid differentiation primary response protein MyD88 isoform 2
|
MYD88
|
cooperates with |
PubMed
|
myosin-11 isoform SM1A
|
MYH11
|
upregulates |
PubMed
|
myosin-9
|
MYH9
|
upregulates |
PubMed
|
myosin light polypeptide 6 isoform 1
|
MYL6
|
upregulates |
PubMed
|
unconventional myosin-Ig
|
MYO1G
|
downregulates |
PubMed
|
nuclear receptor coactivator 1 isoform 1
|
NCOA1
|
enhances |
PubMed
|
NADH dehydrogenase
|
NDUFS8
|
interacts with |
PubMed
|
|
NDUFV3
|
upregulates |
PubMed
|
E3 ubiquitin-protein ligase NEDD4-like isoform 3
|
NEDD4L
|
interacts with |
PubMed
|
neurofilament medium polypeptide isoform 1
|
NEFM
|
downregulates |
PubMed
|
nuclear factor of activated T-cells, cytoplasmic 1 isoform B
|
NFATC1
|
induces |
PubMed
|
|
NFATC1
|
stimulates |
PubMed
|
|
NFATC1
|
upregulates |
PubMed
|
nuclear factor of activated T-cells, cytoplasmic 2 isoform B
|
NFATC2
|
upregulates |
PubMed
|
nuclear factor of activated T-cells, cytoplasmic 3 isoform 2
|
NFATC3
|
upregulates |
PubMed
|
nuclear factor of activated T-cells, cytoplasmic 4 isoform 2
|
NFATC4
|
upregulates |
PubMed
|
nuclear factor NF-kappa-B p105 subunit isoform 1
|
NFKB1
|
activates |
PubMed
|
|
NFKB1
|
activates |
PubMed
|
|
NFKB1
|
activates |
PubMed
|
|
NFKB1
|
enhances |
PubMed
|
|
NFKB1
|
involves |
PubMed
|
|
NFKB1
|
involves |
PubMed
|
|
NFKB1
|
involves |
PubMed
|
|
NFKB1
|
involves |
PubMed
|
|
NFKB1
|
inhibits |
PubMed
|
|
NFKB1
|
regulates |
PubMed
|
|
NFKB1
|
activates |
PubMed
|
|
NFKB1
|
regulated by |
PubMed
|
|
NFKB1
|
activates |
PubMed
|
|
NFKB1
|
inhibits |
PubMed
|
|
NFKB1
|
activates |
PubMed
|
|
NFKB1
|
inhibits |
PubMed
|
|
NFKB1
|
activates |
PubMed
|
|
NFKB1
|
activates |
PubMed
|
|
NFKB1
|
activates |
PubMed
|
|
NFKB1
|
activates |
PubMed
|
|
NFKB1
|
interacts with |
PubMed
|
|
NFKB1
|
downregulates |
PubMed
|
|
NFKB1
|
inhibits |
PubMed
|
nuclear factor NF-kappa-B p100 subunit isoform b
|
NFKB2
|
induces phosphorylation of |
PubMed
|
NF-kappa-B inhibitor alpha
|
NFKBIA
|
induces phosphorylation of |
PubMed
|
|
NFKBIA
|
upregulates |
PubMed
|
|
NFKBIA
|
upregulates |
PubMed
|
NF-kappa-B inhibitor beta isoform 1
|
NFKBIB
|
induces phosphorylation of |
PubMed
|
|
NFKBIB
|
upregulates |
PubMed
|
beta-nerve growth factor precursor
|
NGF
|
inhibited by |
PubMed
|
nucleotide-binding oligomerization domain-containing protein 2 isoform 2
|
NOD2
|
upregulates |
PubMed
|
non-POU domain-containing octamer-binding protein isoform 1
|
NONO
|
upregulates |
PubMed
|
nitric oxide synthase, inducible
|
NOS2
|
upregulates |
PubMed
|
nucleophosmin isoform 1
|
NPM1
|
downregulates |
PubMed
|
glucocorticoid receptor isoform alpha
|
NR3C1
|
interacts with |
PubMed
|
|
NR3C1
|
interacts with |
PubMed
|
|
NR3C1
|
activates |
PubMed
|
|
NR3C1
|
activates |
PubMed
|
|
NR3C1
|
activates |
PubMed
|
|
NR3C1
|
complexes with |
PubMed
|
|
NR3C1
|
activates |
PubMed
|
|
NR3C1
|
activates |
PubMed
|
|
NR3C1
|
activates |
PubMed
|
|
NR3C1
|
activates |
PubMed
|
|
NR3C1
|
activates |
PubMed
|
|
NR3C1
|
activates |
PubMed
|
|
NR3C1
|
activates |
PubMed
|
nuclear receptor subfamily 4immunitygroup A member 1 isoform 1
|
NR4A1
|
downregulates |
PubMed
|
high affinity nerve growth factor receptor isoform 2 precursor
|
NTRK1
|
downregulates |
PubMed
|
nuclear pore complex protein Nup153 isoform 2
|
NUP153
|
interacts with |
PubMed
|
nucleoporin NUP42 isoform 2
|
NUP42
|
affects |
PubMed
|
|
NUP42
|
binds |
PubMed
|
|
NUP42
|
interacts with |
PubMed
|
nucleoporin p54 isoform 1
|
NUP54
|
binds |
PubMed
|
nuclear pore complex protein Nup85 isoform 1
|
NUP85
|
induces accumulation of |
PubMed
|
2'-5'-oligoadenylate synthase 1 isoform 3
|
OAS1
|
antagonizes |
PubMed
|
2'-5'-oligoadenylate synthase 2 isoform 3
|
OAS2
|
upregulates |
PubMed
|
2'-5'-oligoadenylate synthase 3 isoform 1
|
OAS3
|
upregulates |
PubMed
|
2'-5'-oligoadenylate synthase-like protein isoform c
|
OASL
|
upregulates |
PubMed
|
2-oxoglutarate dehydrogenase complex component E1 isoform 1 precursor
|
OGDH
|
upregulates |
PubMed
|
dynamin-like GTPase OPA1, mitochondrial isoform 1 preproprotein
|
OPA1
|
upregulates |
PubMed
|
protein disulfide-isomerase precursor
|
P4HB
|
upregulates |
PubMed
|
proliferation-associated protein 2G4
|
PA2G4
|
downregulates |
PubMed
|
poly(A) polymerase alpha isoform 1
|
PAPOLA
|
decreases phosphorylation of |
PubMed
|
poly
|
PARP1
|
recruits |
PubMed
|
|
PARP1
|
induces cleavage of |
PubMed
|
pericentrin isoform 1
|
PCNT
|
induces accumulation of |
PubMed
|
proprotein convertase subtilisin/kexin type 5 isoform PC6A preproprotein
|
PCSK5
|
cleaved by |
PubMed
|
proprotein convertase subtilisin/kexin type 6 isoform PACE4-AI preproprotein
|
PCSK6
|
involves |
PubMed
|
|
PCSK6
|
cleaves |
PubMed
|
|
PCSK6
|
cleaved by |
PubMed
|
pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform 1 precursor
|
PDHA1
|
induces phosphorylation of |
PubMed
|
protein disulfide-isomerase A3 precursor
|
PDIA3
|
downregulates |
PubMed
|
pyruvate dehydrogenase kinase, isozyme 4
|
PDK4
|
enhances |
PubMed
|
|
PDK4
|
enhances |
PubMed
|
platelet endothelial cell adhesion molecule precursor
|
PECAM1
|
upregulates |
PubMed
|
profilin-1 isoform 2
|
PFN1
|
downregulates |
PubMed
|
membrane-associated progesterone receptor component 2
|
PGRMC2
|
upregulates |
PubMed
|
prohibitin 1 isoform 1
|
PHB1
|
downregulates |
PubMed
|
|
PHB1
|
modulates |
PubMed
|
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
|
PIK3CA
|
involves |
PubMed
|
|
PIK3CA
|
involves |
PubMed
|
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform 2
|
PIK3CB
|
involves |
PubMed
|
|
PIK3CB
|
involves |
PubMed
|
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform 1
|
PIK3CD
|
involves |
PubMed
|
|
PIK3CD
|
involves |
PubMed
|
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
|
PIK3CG
|
involves |
PubMed
|
|
PIK3CG
|
involves |
PubMed
|
pyruvate kinase PKM isoform a
|
PKM
|
upregulates |
PubMed
|
plectin isoform 1c
|
PLEC
|
upregulates |
PubMed
|
serine/threonine-protein kinase PLK1
|
PLK1
|
affects |
PubMed
|
|
PLK1
|
interacts with |
PubMed
|
DNA polymerase alpha catalytic subunit isoform 1
|
POLA1
|
downregulates |
PubMed
|
DNA-directed RNA polymerase II subunit RPB1
|
POLR2A
|
activates |
PubMed
|
DNA-directed RNA polymerase II subunit RPB3
|
POLR2C
|
activates |
PubMed
|
DNA-directed RNA polymerase II subunit RPB4
|
POLR2D
|
activates |
PubMed
|
DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform a
|
POLR2E
|
activates |
PubMed
|
DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform 1
|
POLR2F
|
activates |
PubMed
|
DNA-directed RNA polymerase II subunit RPB7
|
POLR2G
|
activates |
PubMed
|
DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform 2
|
POLR2H
|
activates |
PubMed
|
DNA-directed RNA polymerase II subunit RPB9
|
POLR2I
|
activates |
PubMed
|
DNA-directed RNA polymerase II subunit RPB11-a isoform 1
|
POLR2J
|
activates |
PubMed
|
DNA-directed RNA polymerases I, II, and III subunit RPABC4
|
POLR2K
|
activates |
PubMed
|
DNA-directed RNA polymerases I, II, and III subunit RPABC5
|
POLR2L
|
activates |
PubMed
|
protein GRINL1A isoform 1
|
POLR2M
|
activates |
PubMed
|
ribonuclease P protein subunit p29
|
POP4
|
downregulates |
PubMed
|
peroxisome proliferator-activated receptor delta isoform 1
|
PPARD
|
cooperates with |
PubMed
|
|
PPARD
|
enhances |
PubMed
|
|
PPARD
|
enhances |
PubMed
|
|
PPARD
|
interacts with |
PubMed
|
peptidyl-prolyl cis-trans isomerase A isoform 1
|
PPIA
|
interacts with |
PubMed
|
|
PPIA
|
enhanced by |
PubMed
|
|
PPIA
|
isomerized by |
PubMed
|
serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform 1
|
PPP2CA
|
binds |
PubMed
|
|
PPP2CA
|
upregulates |
PubMed
|
|
PPP2CA
|
activates |
PubMed
|
serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
|
PPP2CB
|
binds |
PubMed
|
|
PPP2CB
|
upregulates |
PubMed
|
|
PPP2CB
|
activates |
PubMed
|
serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform 1
|
PPP2R1A
|
interacts with |
PubMed
|
|
PPP2R1A
|
interacts with |
PubMed
|
|
PPP2R1A
|
interacts with |
PubMed
|
|
PPP2R1A
|
binds |
PubMed
|
|
PPP2R1A
|
upregulates |
PubMed
|
|
PPP2R1A
|
activates |
PubMed
|
serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform a
|
PPP2R1B
|
binds |
PubMed
|
|
PPP2R1B
|
upregulates |
PubMed
|
|
PPP2R1B
|
activates |
PubMed
|
serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform 1
|
PPP2R2A
|
binds |
PubMed
|
|
PPP2R2A
|
activates |
PubMed
|
|
PPP2R2A
|
upregulates |
PubMed
|
|
PPP2R2A
|
activates |
PubMed
|
serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform a
|
PPP2R2B
|
binds |
PubMed
|
|
PPP2R2B
|
activates |
PubMed
|
|
PPP2R2B
|
upregulates |
PubMed
|
|
PPP2R2B
|
activates |
PubMed
|
protein phosphatase 2, regulatory subunit B, gamma isoform b
|
PPP2R2C
|
activates |
PubMed
|
|
PPP2R2C
|
upregulates |
PubMed
|
|
PPP2R2C
|
activates |
PubMed
|
serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform 1
|
PPP2R3A
|
binds |
PubMed
|
|
PPP2R3A
|
activates |
PubMed
|
|
PPP2R3A
|
upregulates |
PubMed
|
|
PPP2R3A
|
activates |
PubMed
|
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform isoform 1
|
PPP2R5A
|
binds |
PubMed
|
|
PPP2R5A
|
upregulates |
PubMed
|
|
PPP2R5A
|
activates |
PubMed
|
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
|
PPP2R5B
|
binds |
PubMed
|
|
PPP2R5B
|
upregulates |
PubMed
|
|
PPP2R5B
|
activates |
PubMed
|
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform a
|
PPP2R5C
|
binds |
PubMed
|
|
PPP2R5C
|
upregulates |
PubMed
|
|
PPP2R5C
|
activates |
PubMed
|
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform 1
|
PPP2R5D
|
binds |
PubMed
|
|
PPP2R5D
|
upregulates |
PubMed
|
|
PPP2R5D
|
activates |
PubMed
|
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform a
|
PPP2R5E
|
binds |
PubMed
|
|
PPP2R5E
|
upregulates |
PubMed
|
|
PPP2R5E
|
activates |
PubMed
|
5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform 1
|
PRKAA1
|
phosphorylated by |
PubMed
|
5'-AMP-activated protein kinase catalytic subunit alpha-2
|
PRKAA2
|
phosphorylated by |
PubMed
|
5'-AMP-activated protein kinase subunit beta-1
|
PRKAB1
|
phosphorylated by |
PubMed
|
5'-AMP-activated protein kinase subunit beta-2
|
PRKAB2
|
phosphorylated by |
PubMed
|
cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1
|
PRKACA
|
interacts with |
PubMed
|
|
PRKACA
|
phosphorylated by |
PubMed
|
cAMP-dependent protein kinase catalytic subunit beta isoform 2
|
PRKACB
|
phosphorylated by |
PubMed
|
cAMP-dependent protein kinase catalytic subunit gamma
|
PRKACG
|
phosphorylated by |
PubMed
|
5'-AMP-activated protein kinase subunit gamma-1 isoform 1
|
PRKAG1
|
phosphorylated by |
PubMed
|
5'-AMP-activated protein kinase subunit gamma-2 isoform a
|
PRKAG2
|
phosphorylated by |
PubMed
|
cAMP-dependent protein kinase type I-alpha regulatory subunit isoform a
|
PRKAR1A
|
phosphorylated by |
PubMed
|
cAMP-dependent protein kinase type I-beta regulatory subunit
|
PRKAR1B
|
phosphorylated by |
PubMed
|
cAMP-dependent protein kinase type II-alpha regulatory subunit isoform a
|
PRKAR2A
|
phosphorylated by |
PubMed
|
cAMP-dependent protein kinase type II-beta regulatory subunit
|
PRKAR2B
|
phosphorylated by |
PubMed
|
protein kinase C iota type
|
PRKCI
|
regulated by |
PubMed
|
protein kinase C zeta type isoform 1
|
PRKCZ
|
regulated by |
PubMed
|
26S proteasome non-ATPase regulatory subunit 2 isoform 1
|
PSMD2
|
interacts with |
PubMed
|
26S proteasome non-ATPase regulatory subunit 4 isoform 2
|
PSMD4
|
interacts with |
PubMed
|
prostaglandin G/H synthase 2 precursor
|
PTGS2
|
downregulates |
PubMed
|
serine/threonine-protein phosphatase 2A activator isoform b
|
PTPA
|
binds |
PubMed
|
|
PTPA
|
activates |
PubMed
|
|
PTPA
|
upregulates |
PubMed
|
|
PTPA
|
activates |
PubMed
|
poliovirus receptor isoform alpha precursor
|
PVR
|
upregulates |
PubMed
|
|
PVR
|
upregulates |
PubMed
|
peroxidasin-like protein precursor
|
PXDNL
|
upregulates |
PubMed
|
ras-related protein Rab-7a
|
RAB7A
|
upregulates |
PubMed
|
cell cycle checkpoint protein RAD17 isoform 1
|
RAD17
|
requires |
PubMed
|
double-strand-break repair protein rad21 homolog
|
RAD21
|
downregulates |
PubMed
|
UV excision repair protein RAD23 homolog A isoform 1
|
RAD23A
|
binds |
PubMed
|
|
RAD23A
|
binds |
PubMed
|
|
RAD23A
|
complexes with |
PubMed
|
|
RAD23A
|
binds |
PubMed
|
|
RAD23A
|
cooperates with |
PubMed
|
|
RAD23A
|
inhibits |
PubMed
|
|
RAD23A
|
binds |
PubMed
|
|
RAD23A
|
inhibited by |
PubMed
|
DNA repair protein RAD51 homolog 1 isoform 1
|
RAD51
|
inhibits |
PubMed
|
|
RAD51
|
stimulates |
PubMed
|
ras-related protein Ral-A precursor
|
RALA
|
upregulates |
PubMed
|
histone-binding protein RBBP7 isoform 2
|
RBBP7
|
complexes with |
PubMed
|
|
RBBP7
|
interacts with |
PubMed
|
retinol dehydrogenase 11 isoform 1
|
RDH11
|
upregulates |
PubMed
|
radixin isoform 2
|
RDX
|
downregulates |
PubMed
|
proto-oncogene c-Rel isoform 1
|
REL
|
upregulates |
PubMed
|
transcription factor p65 isoform 1
|
RELA
|
activates |
PubMed
|
|
RELA
|
regulated by |
PubMed
|
|
RELA
|
induces phosphorylation of |
PubMed
|
|
RELA
|
inhibits |
PubMed
|
|
RELA
|
downregulates |
PubMed
|
|
RELA
|
cooperates with |
PubMed
|
|
RELA
|
inhibits |
PubMed
|
|
RELA
|
activates |
PubMed
|
transcription factor RelB isoform 1
|
RELB
|
interacts with |
PubMed
|
|
RELB
|
cooperates with |
PubMed
|
|
RELB
|
interacts with |
PubMed
|
transforming protein RhoA isoform 1 precursor
|
RHOA
|
upregulates |
PubMed
|
rho-related GTP-binding protein RhoB
|
RHOB
|
upregulates |
PubMed
|
rho-related GTP-binding protein RhoG
|
RHOG
|
upregulates |
PubMed
|
antiviral innate immune response receptor RIG-I isoform 1
|
RIGI
|
upregulates |
PubMed
|
|
RIGI
|
upregulates |
PubMed
|
receptor-interacting serine/threonine-protein kinase 1 isoform 1
|
RIPK1
|
upregulates |
PubMed
|
GTP-binding protein Rit1 isoform 2
|
RIT1
|
induces complex with |
PubMed
|
proto-oncogene tyrosine-protein kinase ROS isoform 1 precursor
|
ROS1
|
upregulates |
PubMed
|
replication protein A 70 kDa DNA-binding subunit isoform 1
|
RPA1
|
interacts with |
PubMed
|
replication protein A 32 kDa subunit isoform 1
|
RPA2
|
complexes with |
PubMed
|
|
RPA2
|
co-localizes with |
PubMed
|
|
RPA2
|
induces phosphorylation of |
PubMed
|
large ribosomal subunit protein uL5 isoform 1
|
RPL11
|
downregulates |
PubMed
|
large ribosomal subunit protein eL13 isoform 1
|
RPL13
|
downregulates |
PubMed
|
large ribosomal subunit protein uL23
|
RPL23A
|
downregulates |
PubMed
|
large ribosomal subunit protein eL29
|
RPL29
|
downregulates |
PubMed
|
large ribosomal subunit protein uL10
|
RPLP0
|
downregulates |
PubMed
|
ribosome-binding protein 1 isoform 2
|
RRBP1
|
upregulates |
PubMed
|
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 isoform 1
|
RSAD2
|
upregulates |
PubMed
|
reticulon-4 isoform C
|
RTN4
|
downregulates |
PubMed
|
protein S100-B
|
S100B
|
upregulates |
PubMed
|
secretory carrier-associated membrane protein 3 isoform 1
|
SCAMP3
|
upregulates |
PubMed
|
scavenger receptor class A member 3 isoform 1
|
SCARA3
|
downregulates |
PubMed
|
lysosome membrane protein 2 isoform 1
|
SCARB2
|
downregulates |
PubMed
|
succinate dehydrogenase
|
SDHA
|
downregulates |
PubMed
|
stress-associated endoplasmic reticulum protein 1
|
SERP1
|
downregulates |
PubMed
|
plasminogen activator inhibitor 2
|
SERPINB2
|
downregulates |
PubMed
|
plasminogen activator inhibitor 1 isoform 2 precursor
|
SERPINE1
|
downregulates |
PubMed
|
splicing factor 3B subunit 2
|
SF3B2
|
inhibits |
PubMed
|
|
SF3B2
|
binds |
PubMed
|
|
SF3B2
|
interacts with |
PubMed
|
splicing factor 3B subunit 4
|
SF3B4
|
inhibits |
PubMed
|
|
SF3B4
|
inhibits |
PubMed
|
shugoshin 1 isoform 1KL
|
SGO1
|
relocalizes |
PubMed
|
|
SGO1
|
inhibits |
PubMed
|
electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial
|
SLC25A12
|
downregulates |
PubMed
|
ADP/ATP translocase 1
|
SLC25A4
|
binds |
PubMed
|
|
SLC25A4
|
binds |
PubMed
|
|
SLC25A4
|
binds |
PubMed
|
ADP/ATP translocase 2
|
SLC25A5
|
downregulates |
PubMed
|
sodium/hydrogen exchanger 1
|
SLC9A1
|
downregulates |
PubMed
|
|
SLC9A1
|
downregulates |
PubMed
|
structure-specific endonuclease subunit SLX4
|
SLX4
|
interacts with |
PubMed
|
|
SLX4
|
regulates |
PubMed
|
|
SLX4
|
activates |
PubMed
|
|
SLX4
|
activates |
PubMed
|
|
SLX4
|
interacts with |
PubMed
|
|
SLX4
|
complexes with |
PubMed
|
protein SLX4IP
|
SLX4IP
|
interacts with |
PubMed
|
mothers against decapentaplegic homolog 3 isoform 1
|
SMAD3
|
activates |
PubMed
|
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
|
SMARCA5
|
binds |
PubMed
|
structural maintenance of chromosomes protein 1A isoform 1
|
SMC1A
|
downregulates |
PubMed
|
structural maintenance of chromosomes protein 1B isoform 1
|
SMC1B
|
downregulates |
PubMed
|
structural maintenance of chromosomes protein 3
|
SMC3
|
downregulates |
PubMed
|
survival motor neuron protein isoform d
|
SMN1
|
downregulates |
PubMed
|
single-strand selective monofunctional uracil DNA glycosylase isoform 1
|
SMUG1
|
downregulates |
PubMed
|
|
SMUG1
|
downregulates |
PubMed
|
|
SMUG1
|
complexes with |
PubMed
|
small nuclear ribonucleoprotein-associated protein N isoform b
|
SNRPN
|
interacts with |
PubMed
|
sorbin and SH3 domain-containing protein 2 isoform 2
|
SORBS2
|
upregulates |
PubMed
|
transcription factor Sp1 isoform a
|
SP1
|
cooperates with |
PubMed
|
|
SP1
|
cooperates with |
PubMed
|
|
SP1
|
interacts with |
PubMed
|
|
SP1
|
interacts with |
PubMed
|
leukosialin precursor
|
SPN
|
antagonizes |
PubMed
|
spectrin alpha chain, non-erythrocytic 1 isoform 1
|
SPTAN1
|
upregulates |
PubMed
|
spectrin beta chain, non-erythrocytic 1 isoform 1
|
SPTBN1
|
co-localizes with |
PubMed
|
sulfide:quinone oxidoreductase, mitochondrial
|
SQOR
|
upregulates |
PubMed
|
lupus La protein
|
SSB
|
downregulates |
PubMed
|
signal transducer and activator of transcription 1-alpha/beta isoform alpha
|
STAT1
|
induces phosphorylation of |
PubMed
|
|
STAT1
|
activates |
PubMed
|
stimulator of interferon genes protein isoform 1
|
STING1
|
antagonizes |
PubMed
|
stomatin-like protein 2, mitochondrial isoform a
|
STOML2
|
downregulates |
PubMed
|
succinate--CoA ligase
|
SUCLG1
|
downregulates |
PubMed
|
histone-lysine N-methyltransferase SUV39H1 isoform 2
|
SUV39H1
|
inhibited by |
PubMed
|
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform 1
|
TAB3
|
interacts with |
PubMed
|
transgelin-2 isoform b
|
TAGLN2
|
upregulates |
PubMed
|
serine/threonine-protein kinase TBK1
|
TBK1
|
interacts with |
PubMed
|
TATA-box-binding protein isoform 1
|
TBP
|
binds |
PubMed
|
transcription factor 12 isoform d
|
TCF12
|
downregulates |
PubMed
|
telomerase reverse transcriptase isoform 1
|
TERT
|
downregulates |
PubMed
|
|
TERT
|
downregulates |
PubMed
|
tesmin isoform a
|
TESMIN
|
downregulates |
PubMed
|
transferrin receptor protein 1 isoform 1
|
TFRC
|
upregulates |
PubMed
|
transforming growth factor beta-1 proprotein preproprotein
|
TGFB1
|
modulates |
PubMed
|
thrombospondin-1 precursor
|
THBS1
|
stimulates |
PubMed
|
metalloproteinase inhibitor 1 precursor
|
TIMP1
|
upregulates |
PubMed
|
thymidine kinase, cytosolic isoform 1
|
TK1
|
upregulates |
PubMed
|
transketolase isoform 1
|
TKT
|
downregulates |
PubMed
|
toll-like receptor 4 isoform A precursor
|
TLR4
|
cooperates with |
PubMed
|
|
TLR4
|
downregulates |
PubMed
|
transmembrane protein 11, mitochondrial
|
TMEM11
|
interacts with |
PubMed
|
transmembrane protein 160 precursor
|
TMEM160
|
interacts with |
PubMed
|
transmembrane protein 33
|
TMEM33
|
upregulates |
PubMed
|
tumor necrosis factor
|
TNF
|
enhances |
PubMed
|
|
TNF
|
upregulates |
PubMed
|
|
TNF
|
cooperates with |
PubMed
|
|
TNF
|
inhibits |
PubMed
|
|
TNF
|
upregulates |
PubMed
|
|
TNF
|
inhibits |
PubMed
|
|
TNF
|
modulates |
PubMed
|
tumor necrosis factor ligand superfamily member 10 isoform 1
|
TNFSF10
|
upregulates |
PubMed
|
tumor necrosis factor ligand superfamily member 11 isoform 1
|
TNFSF11
|
upregulates |
PubMed
|
tumor necrosis factor ligand superfamily member 15 isoform VEGI-192
|
TNFSF15
|
upregulates |
PubMed
|
tumor necrosis factor ligand superfamily member 9
|
TNFSF9
|
upregulates |
PubMed
|
transportin-1 isoform 1
|
TNPO1
|
interacts with |
PubMed
|
|
TNPO1
|
regulates |
PubMed
|
mitochondrial import receptor subunit TOM22 homolog
|
TOMM22
|
downregulates |
PubMed
|
cellular tumor antigen p53 isoform a
|
TP53
|
interacts with |
PubMed
|
|
TP53
|
upregulates |
PubMed
|
|
TP53
|
upregulates |
PubMed
|
|
TP53
|
upregulates |
PubMed
|
|
TP53
|
inhibits |
PubMed
|
|
TP53
|
interacts with |
PubMed
|
|
TP53
|
regulated by |
PubMed
|
|
TP53
|
activates |
PubMed
|
|
TP53
|
inhibits |
PubMed
|
TP53-binding protein 1 isoform 3
|
TP53BP1
|
interacts with |
PubMed
|
|
TP53BP1
|
co-localizes with |
PubMed
|
triosephosphate isomerase isoform 1
|
TPI1
|
downregulates |
PubMed
|
transformer-2 protein homolog alpha isoform 1
|
TRA2A
|
activated by |
PubMed
|
transformer-2 protein homolog beta isoform 1
|
TRA2B
|
activated by |
PubMed
|
TNF receptor-associated factor 1 isoform a
|
TRAF1
|
mediated by |
PubMed
|
TNF receptor-associated factor 2
|
TRAF2
|
mediated by |
PubMed
|
TNF receptor-associated factor 6
|
TRAF6
|
interacts with |
PubMed
|
|
TRAF6
|
interacts with |
PubMed
|
E3 ubiquitin-protein ligase TRIM11
|
TRIM11
|
regulates |
PubMed
|
transient receptor potential cation channel subfamily V member 2
|
TRPV2
|
upregulates |
PubMed
|
tumor susceptibility gene 101 protein
|
TSG101
|
competes with |
PubMed
|
|
TSG101
|
abrogates |
PubMed
|
testis-specific Y-encoded-like protein 1
|
TSPYL1
|
interacts with |
PubMed
|
tubulin beta-3 chain isoform 1
|
TUBB3
|
downregulates |
PubMed
|
tubulin gamma-1 chain
|
TUBG1
|
induces accumulation of |
PubMed
|
tubulin gamma-2 chain isoform 2
|
TUBG2
|
induces accumulation of |
PubMed
|
tubby-related protein 3 isoform 1
|
TULP3
|
interacts with |
PubMed
|
thioredoxin-interacting protein isoform 2
|
TXNIP
|
upregulates |
PubMed
|
ubiquitin-ribosomal protein eL40 fusion protein isoform 1 precursor
|
UBA52
|
upregulates |
PubMed
|
ubiquitin-associated protein 2-like isoform a
|
UBAP2L
|
upregulates |
PubMed
|
polyubiquitin-B precursor
|
UBB
|
complexes with |
PubMed
|
|
UBB
|
cooperates with |
PubMed
|
polyubiquitin-C
|
UBC
|
complexes with |
PubMed
|
|
UBC
|
cooperates with |
PubMed
|
ubiquitin D
|
UBD
|
co-localizes with |
PubMed
|
|
UBD
|
upregulates |
PubMed
|
E3 ubiquitin-protein ligase UBR1
|
UBR1
|
induces complex with |
PubMed
|
E3 ubiquitin-protein ligase UBR2 isoform 1
|
UBR2
|
complexes with |
PubMed
|
E3 ubiquitin-protein ligase UBR3
|
UBR3
|
complexes with |
PubMed
|
E3 ubiquitin-protein ligase UBR4
|
UBR4
|
complexes with |
PubMed
|
E3 ubiquitin-protein ligase UBR5 isoform 1
|
UBR5
|
interacts with |
PubMed
|
|
UBR5
|
complexes with |
PubMed
|
UL16-binding protein 1 isoform 1 precursor
|
ULBP1
|
upregulates |
PubMed
|
|
ULBP1
|
upregulates |
PubMed
|
|
ULBP1
|
upregulates |
PubMed
|
|
ULBP1
|
upregulates |
PubMed
|
|
ULBP1
|
upregulates |
PubMed
|
UL16-binding protein 2 preproprotein
|
ULBP2
|
upregulates |
PubMed
|
|
ULBP2
|
upregulates |
PubMed
|
|
ULBP2
|
upregulates |
PubMed
|
|
ULBP2
|
upregulates |
PubMed
|
|
ULBP2
|
upregulates |
PubMed
|
|
ULBP2
|
upregulates |
PubMed
|
|
ULBP2
|
upregulates |
PubMed
|
UL16-binding protein 3
|
ULBP3
|
upregulates |
PubMed
|
|
ULBP3
|
upregulates |
PubMed
|
|
ULBP3
|
upregulates |
PubMed
|
|
ULBP3
|
upregulates |
PubMed
|
uracil-DNA glycosylase isoform UNG2
|
UNG
|
inhibits |
PubMed
|
|
UNG
|
mimics DNA binding to |
PubMed
|
|
UNG
|
depletes |
PubMed
|
|
UNG
|
targets |
PubMed
|
|
UNG
|
binds |
PubMed
|
|
UNG
|
downregulates |
PubMed
|
|
UNG
|
downregulates |
PubMed
|
|
UNG
|
complexes with |
PubMed
|
|
UNG
|
induces ubiquitination of |
PubMed
|
|
UNG
|
degrades |
PubMed
|
|
UNG
|
degrades |
PubMed
|
|
UNG
|
degrades |
PubMed
|
|
UNG
|
binds |
PubMed
|
|
UNG
|
downregulates |
PubMed
|
|
UNG
|
complexes with |
PubMed
|
|
UNG
|
binds |
PubMed
|
|
UNG
|
induces phosphorylation of |
PubMed
|
|
UNG
|
activates |
PubMed
|
|
UNG
|
interacts with |
PubMed
|
|
UNG
|
binds |
PubMed
|
|
UNG
|
incorporates |
PubMed
|
|
UNG
|
induces ubiquitination of |
PubMed
|
|
UNG
|
incorporates |
PubMed
|
|
UNG
|
binds |
PubMed
|
general vesicular transport factor p115 isoform 2
|
USO1
|
upregulates |
PubMed
|
ubl carboxyl-terminal hydrolase 18
|
USP18
|
upregulates |
PubMed
|
synaptic vesicle membrane protein VAT-1 homolog
|
VAT1
|
upregulates |
PubMed
|
non-selective voltage-gated ion channel VDAC1 isoform 1
|
VDAC1
|
downregulates |
PubMed
|
|
VDAC1
|
interacts with |
PubMed
|
|
VDAC1
|
interacts with |
PubMed
|
voltage-dependent anion-selective channel protein 2 isoform 2
|
VDAC2
|
downregulates |
PubMed
|
|
VDAC2
|
interacts with |
PubMed
|
voltage-dependent anion-selective channel protein 3 isoform 1
|
VDAC3
|
interacts with |
PubMed
|
vimentin
|
VIM
|
downregulates |
PubMed
|
|
VIM
|
modulates |
PubMed
|
wee1-like protein kinase isoform 1
|
WEE1
|
downregulates |
PubMed
|
|
WEE1
|
binds |
PubMed
|
|
WEE1
|
upregulates |
PubMed
|
|
WEE1
|
interacts with |
PubMed
|
|
WEE1
|
inhibited by |
PubMed
|
|
WEE1
|
induces release of |
PubMed
|
XIAP-associated factor 1 isoform 1
|
XAF1
|
upregulates |
PubMed
|
exportin-1 isoform 1
|
XPO1
|
exported by |
PubMed
|
|
XPO1
|
exported by |
PubMed
|
14-3-3 protein beta/alpha
|
YWHAB
|
inhibits |
PubMed
|
|
YWHAB
|
enhanced by |
PubMed
|
14-3-3 protein epsilon
|
YWHAE
|
inhibits |
PubMed
|
|
YWHAE
|
enhanced by |
PubMed
|
14-3-3 protein gamma
|
YWHAG
|
inhibits |
PubMed
|
|
YWHAG
|
inhibits |
PubMed
|
|
YWHAG
|
enhanced by |
PubMed
|
14-3-3 protein eta
|
YWHAH
|
inhibits |
PubMed
|
|
YWHAH
|
complexes with |
PubMed
|
|
YWHAH
|
binds |
PubMed
|
|
YWHAH
|
enhanced by |
PubMed
|
14-3-3 protein theta
|
YWHAQ
|
interacts with |
PubMed
|
|
YWHAQ
|
inhibits |
PubMed
|
|
YWHAQ
|
binds |
PubMed
|
14-3-3 protein zeta/delta
|
YWHAZ
|
interacts with |
PubMed
|
|
YWHAZ
|
inhibits |
PubMed
|
|
YWHAZ
|
enhanced by |
PubMed
|
Z-DNA-binding protein 1 isoform b
|
ZBP1
|
upregulates |
PubMed
|
zinc finger CCCH-type with G patch domain-containing protein isoform a
|
ZGPAT
|
degrades |
PubMed
|
|
ZGPAT
|
complexes with |
PubMed
|
zinc finger protein 512 isoform a
|
ZNF512
|
downregulates |
PubMed
|
zinc finger-containing ubiquitin peptidase 1 isoform 1
|
ZUP1
|
downregulates |
PubMed
|