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    HERC2P2 HERC2 pseudogene 2 [ Homo sapiens (human) ]

    Gene ID: 400322, updated on 22-Oct-2024

    Summary

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    Official Symbol
    HERC2P2provided by HGNC
    Official Full Name
    HERC2 pseudogene 2provided by HGNC
    Primary source
    HGNC:HGNC:4870
    See related
    Ensembl:ENSG00000291003 AllianceGenome:HGNC:4870
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MN7; D15F37S3
    Expression
    Ubiquitous expression in urinary bladder (RPKM 32.1), brain (RPKM 25.7) and 25 other tissues See more
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    Genomic context

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    See HERC2P2 in Genome Data Viewer
    Location:
    15q11.2
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (22494837..22590831)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (20166952..20262941)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (23282265..23378259, complement)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene pectinesterase inhibitor 10-like Neighboring gene HERC2 pseudogene 7 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:23375324-23375978 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:23311731-23312230 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:23306154-23306733 Neighboring gene HECT and RLD domain containing E3 ubiquitin protein ligase 2 pseudogene Neighboring gene uncharacterized LOC101927846 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:23263501-23264001 Neighboring gene RNA, 7SL, cytoplasmic 495, pseudogene Neighboring gene golgin A8 family member I, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Identification of long non-coding RNA HERC2P2 as a tumor suppressor in glioma. Yang C, et al. Carcinogenesis, 2019 Aug 22. PMID 30809632
    2. A putative gene family in 15q11-13 and 16p11.2: possible implications for Prader-Willi and Angelman syndromes. Buiting K, et al. Proc Natl Acad Sci U S A, 1992 Jun 15. PMID 1608955, Free PMC Article
    3. Expressed copies of the MN7 (D15F37) gene family map close to the common deletion breakpoints in the Prader-Willi/Angelman syndromes. Buiting K, et al. Cytogenet Cell Genet, 1998. PMID 9730612
    4. The ancestral gene for transcribed, low-copy repeats in the Prader-Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities. Ji Y, et al. Hum Mol Genet, 1999 Mar. PMID 9949213
    5. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. Nagase T, et al. DNA Res, 1997 Apr 28. PMID 9205841

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • hect domain and RLD 2 pseudogene 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_002824.3 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AA976147, AB002391, AC100757, AF041080, DB069140
      Related
      ENST00000619021.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      22494837..22590831
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_021160017.1 Reference GRCh38.p14 PATCHES

      Range
      3388384..3485185
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_1

    Genomic

    1. NT_187604.1 Reference GRCh38.p14 ALT_REF_LOCI_1

      Range
      138448..235204
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      20166952..20262941
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001024681.1: Suppressed sequence

      Description
      NM_001024681.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
    Nucleotide Protein
    Heading Accession and Version

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