ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ndufs7provided by ZNC
Official Full Name: NADH:ubiquinone oxidoreductase core subunit S7provided by ZNC
Primary source: ZFIN:ZDB-GENE-041111-261
See related: Ensembl:ENSDARG00000074552 AllianceGenome:ZFIN:ZDB-GENE-041111-261
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fj19d10; im:7149436; wu:fj19d10
Summary: Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in aerobic respiration; electron transport coupled proton transport; and mitochondrial respiratory chain complex I assembly. Predicted to be part of respiratory chain complex I. Is expressed in several structures, including eye; immature eye; musculature system; optic tectum; and pharyngeal arch 3-7 skeleton. Human ortholog(s) of this gene implicated in developmental disorder of mental health and nuclear type mitochondrial complex I deficiency 3. Orthologous to human NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 11

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (5842648..5852732)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (5845393..5855477)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fj19d10.x1 (e-PCR)
- UniSTS:198710

fc06a12.x1 (e-PCR)
- UniSTS:192227

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 4 iron, 4 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables NADH dehydrogenase (ubiquinone) activity	IBA Inferred from Biological aspect of Ancestor more info
enables NADH dehydrogenase (ubiquinone) activity	IEA Inferred from Electronic Annotation more info
enables iron-sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables quinone binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in aerobic respiration	IBA Inferred from Biological aspect of Ancestor more info
involved_in electron transport coupled proton transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial respiratory chain complex I assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

Names: NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)

NP_001186841.1

EC 7.1.1.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001199912.1 → NP_001186841.1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

Status: VALIDATED

Source sequence(s)

BX323045, EH455252, EH542385

UniProtKB/TrEMBL

A0A8M1NVL4, F1QHE9

Related

ENSDARP00000098301.3, ENSDART00000111374.4

Conserved Domains (1) summary

PRK06411
Location:67 → 214

PRK06411; NADH dehydrogenase subunit B; Validated