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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029624.1 RefSeqGene
- Range
-
5270..14190
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001243116.2 → NP_001230045.1 NF-kappa-B inhibitor beta isoform 2
See identical proteins and their annotated locations for NP_001230045.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) contains an alternate 5' terminal exon compared to variant 1. This results in translation initiation from an in-frame downstream AUG, and a shorter isoform (2) compared to isoform 1.
- Source sequence(s)
-
AC011455, AI684894, BC015528, BI520169
- Consensus CDS
-
CCDS74362.1
- UniProtKB/TrEMBL
- G5E9C2, I3L4X3
- Related
- ENSP00000375929.4, ENST00000392079.7
- Conserved Domains (3) summary
-
- cd00204
Location:2 → 175
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam12796
Location:125 → 212
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:120 → 151
- ANK; ANK repeat [structural motif]
-
NM_001369699.1 → NP_001356628.1 NF-kappa-B inhibitor beta isoform 3
Status: REVIEWED
- Source sequence(s)
-
AB209784, AC011455
- Consensus CDS
-
CCDS92612.1
- UniProtKB/TrEMBL
-
Q59EM7
- Related
- ENSP00000459728.1, ENST00000572515.5
- Conserved Domains (3) summary
-
- PHA03095
Location:203 → 298
- PHA03095; ankyrin-like protein; Provisional
- COG0666
Location:57 → 148
- ANKYR; Ankyrin repeat [Signal transduction mechanisms]
- sd00045
Location:206 → 237
- ANK; ANK repeat [structural motif]
-
NM_001369700.1 → NP_001356629.1 NF-kappa-B inhibitor beta isoform 4
Status: REVIEWED
- Source sequence(s)
-
AC011455
- Conserved Domains (3) summary
-
- PHA03095
Location:111 → 206
- PHA03095; ankyrin-like protein; Provisional
- sd00045
Location:114 → 145
- ANK; ANK repeat [structural motif]
- pfam12796
Location:52 → 142
- Ank_2; Ankyrin repeats (3 copies)
-
NM_002503.5 → NP_002494.2 NF-kappa-B inhibitor beta isoform 1
See identical proteins and their annotated locations for NP_002494.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the predominant transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AI684894, BC015528, DA633677
- Consensus CDS
-
CCDS12524.1
- UniProtKB/Swiss-Prot
- A8K3F4, Q15653, Q96BJ7
- UniProtKB/TrEMBL
-
Q59EM7
- Related
- ENSP00000312988.5, ENST00000313582.6
- Conserved Domains (4) summary
-
- COG0666
Location:240 → 299
- ANKYR; Ankyrin repeat [Signal transduction mechanisms]
- cd00204
Location:88 → 261
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- sd00045
Location:206 → 237
- ANK; ANK repeat [structural motif]
- pfam12796
Location:52 → 118
- Ank_2; Ankyrin repeats (3 copies)
RNA
-
NR_040515.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate acceptor splice site at the second exon, and is alternatively spliced at the 3' end compared to variant 1. It is represented as non-coding due to the presence of an upstream ORF (with a strong Kozak signal) that is predicted to interfere with the translation of the downstream longer ORF; translation of the upstream ORF renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AA044256, AB209784, AK057862, BX111397, DA633677
- Related
-
ENST00000509705.3
-
NR_161470.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC011455
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000019.10 Reference GRCh38.p14 Primary Assembly
- Range
-
38899666..38908889
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006723227.4 → XP_006723290.4 NF-kappa-B inhibitor beta isoform X2
- UniProtKB/TrEMBL
- G5E9C2, I3L4X3
-
XM_006723226.3 → XP_006723289.2 NF-kappa-B inhibitor beta isoform X1
- UniProtKB/TrEMBL
-
Q96LS1
- Conserved Domains (3) summary
-
- cd00204
Location:56 → 229
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam12796
Location:179 → 266
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:174 → 205
- ANK; ANK repeat [structural motif]
Reference GRCh38.p14 PATCHES
Genomic
-
NW_014040929.1 Reference GRCh38.p14 PATCHES
- Range
-
309338..318561
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054331970.1 → XP_054187945.1 NF-kappa-B inhibitor beta isoform X2
- UniProtKB/TrEMBL
- G5E9C2, I3L4X3
-
XM_054331969.1 → XP_054187944.1 NF-kappa-B inhibitor beta isoform X1
- UniProtKB/TrEMBL
-
Q96LS1
Alternate T2T-CHM13v2.0
Genomic
-
NC_060943.1 Alternate T2T-CHM13v2.0
- Range
-
41703721..41712860
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054321077.1 → XP_054177052.1 NF-kappa-B inhibitor beta isoform X2
- UniProtKB/TrEMBL
- G5E9C2, I3L4X3
-
XM_054321076.1 → XP_054177051.1 NF-kappa-B inhibitor beta isoform X1
- UniProtKB/TrEMBL
-
Q96LS1
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001001716.1: Suppressed sequence
- Description
- NM_001001716.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.