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    idh1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541894, updated on 11-Sep-2024

    Summary

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    Official Symbol
    idh1
    Primary source
    PomBase:SPAC11G7.03
    Locus tag
    SPOM_SPAC11G7.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    glu3
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3966766..3968132)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein Mtl2 Neighboring gene HECT-type ubiquitin-protein ligase E3 Pub1 Neighboring gene ncRNA Neighboring gene ubiquitin-60S ribosomal protein L40 fusion protein Neighboring gene S-malonyltransferase Mct1 Neighboring gene protein Mug132

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and RNA-binding analysis of NAD+ -isocitrate dehydrogenases from Kluyveromyces lactis and Schizosaccharomyces pombe. Elzinga SD, et al. Curr Genet, 2000 Aug. PMID 10975257
    2. Enzyme defects in glutamate-requiring strains of Schizosaccharomyces pombe. Barel I, et al. FEMS Microbiol Lett, 1993 Nov 1. PMID 7903653
    3. TORC2 and the AGC kinase Gad8 regulate phosphorylation of the ribosomal protein S6 in fission yeast. Du W, et al. Biol Open, 2012 Sep 15. PMID 23213482, Free PMC Article
    4. Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis. Snaith HA, et al. J Cell Sci, 2011 Jul 1. PMID 21652630, Free PMC Article
    5. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to isocitrate dehydrogenase (NAD+) activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables isocitrate dehydrogenase (NAD+) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in isocitrate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tricarboxylic acid cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tricarboxylic acid cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm HDA PubMed 
    part_of isocitrate dehydrogenase complex (NAD+) ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    isocitrate dehydrogenase (NAD+) subunit 1 Idh1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3966766..3968132
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019820.3 → NP_594397.1  isocitrate dehydrogenase (NAD+) subunit 1 Idh1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594397.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13696
      Conserved Domains (1) summary
      TIGR00175
      Location:18 → 353
      mito_nad_idh; isocitrate dehydrogenase, NAD-dependent, mitochondrial type
    Nucleotide Protein
    Heading Accession and Version

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