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    FIBIN fin bud initiation factor homolog [ Homo sapiens (human) ]

    Gene ID: 387758, updated on 28-Oct-2024

    Summary

    Official Symbol
    FIBINprovided by HGNC
    Official Full Name
    fin bud initiation factor homologprovided by HGNC
    Primary source
    HGNC:HGNC:33747
    See related
    Ensembl:ENSG00000176971 MIM:617085; AllianceGenome:HGNC:33747
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to enable protein homodimerization activity. Predicted to be involved in protein kinase C signaling; response to dexamethasone; and response to manganese ion. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and extracellular region. [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
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    Genomic context

    See FIBIN in Genome Data Viewer
    Location:
    11p14.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (26994112..26997087)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (27134604..27137579)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (27015659..27018634)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902649 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:26971346-26971846 Neighboring gene 11p14.2 distal LINE-mediated recombination region Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:26986897-26987409 Neighboring gene uncharacterized LOC124902650 Neighboring gene BBOX1 antisense RNA 1 Neighboring gene gamma-butyrobetaine hydroxylase 1 Neighboring gene uncharacterized LOC124902651

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC24932

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    fin bud initiation factor homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_203371.2NP_976249.1  fin bud initiation factor homolog precursor

      See identical proteins and their annotated locations for NP_976249.1

      Status: VALIDATED

      Source sequence(s)
      AA452778, AI755024, BC026873, BQ882486, CB962364, D79377
      Consensus CDS
      CCDS7861.1
      UniProtKB/Swiss-Prot
      Q8TAL6
      Related
      ENSP00000321962.2, ENST00000318627.4
      Conserved Domains (1) summary
      pfam15819
      Location:15210
      Fibin; Fin bud initiation factor homolog

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      26994112..26997087
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      27134604..27137579
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)