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    ankfn1a ankyrin repeat and fibronectin type III domain containing 1a [ Danio rerio (zebrafish) ]

    Gene ID: 100333998, updated on 25-Apr-2024

    Summary

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    Official Symbol
    ankfn1aprovided by ZNC
    Official Full Name
    ankyrin repeat and fibronectin type III domain containing 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-130603-21
    See related
    AllianceGenome:ZFIN:ZDB-GENE-130603-21
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ankfn1; si:ch211-277e21.2
    Summary
    Predicted to be involved in establishment of mitotic spindle orientation and regulation of establishment of bipolar cell polarity. Predicted to be active in spindle. Orthologous to human ANKFN1 (ankyrin repeat and fibronectin type III domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See ankfn1a in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (32191733..32374814)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (32076738..32260308)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene si:ch73-256g18.2 Neighboring gene transmembrane protein 100b Neighboring gene noggin 3 Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Variable phenotypes and penetrance between and within different zebrafish ciliary transition zone mutants. Wang J, et al. Dis Model Mech, 2022 Dec 1. PMID 36533556, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within neuromuscular process controlling posture IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within thigmotaxis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ankyrin repeat and fibronectin type-III domain-containing protein 1
    Names
    Ankyrin repeat and fibronectin type-III domain-containing protein 1
    ankyrin repeat and fibronectin type III domain containing 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      32191733..32374814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480370.1 → XP_021336045.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1

      UniProtKB/Swiss-Prot
      A0A8M9QN10
      UniProtKB/TrEMBL
      A0A9V2V100
      Conserved Domains (3) summary
      cd00063
      Location:554 → 640
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      sd00045
      Location:423 → 454
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:423 → 480
      Ank_2; Ankyrin repeats (3 copies)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394854.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      6420..181539
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021472578.1 → XP_021328253.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PMH9
      Conserved Domains (3) summary
      cd00063
      Location:548 → 634
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      sd00045
      Location:417 → 448
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:417 → 474
      Ank_2; Ankyrin repeats (3 copies)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395303.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      2956..181749
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009306802.3 → XP_009305077.2  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8M3AYI6
      Conserved Domains (3) summary
      cd00063
      Location:448 → 534
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      sd00045
      Location:317 → 348
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:317 → 374
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A8M9QN10.1 GenPept UniProtKB/Swiss-Prot:A0A8M9QN10

    Gene LinkOut

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