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Series GSE103220 Query DataSets for GSE103220
Status Public on Dec 11, 2019
Title Genome-wide microRNA expression in WT and RBP-J KO BMDMs
Organism Mus musculus
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary RBP-J is a master transcriptional factor of Notch signaling, which plays important roles in developmental processes as well as regulating macrophage-mediated inflammatory responses. However, the regulation of RBP-J on miRNAs are less studied. So we sequenced microRNAs from BMDMs derived from the LyZ2 Cre control (WT) and RBP-J conditional knockout mice (RBP-J KO; Rbpjf/f LyZ2 Cre) to address the roles of RBP-J on regulating miRNAs in macrophages.
 
Overall design Examination of differential microRNA expression levels in unstimulated BMDMs from WT and RBP-J KO mice
 
Contributor(s) Zhang X, Smith SM, Zhang B
Citation(s) 31944217
Submission date Aug 29, 2017
Last update date Mar 12, 2020
Contact name Xiang Zhang
E-mail(s) zinsservictor@gmail.com
Organization name Tsinghua University
Street address Tsinghuayuan Street
City Beijing
ZIP/Postal code 100084
Country China
 
Platforms (1)
GPL18480 Illumina HiSeq 1500 (Mus musculus)
Samples (2)
GSM2757558 WT without stimulation
GSM2757559 RBP-J KO without stimulation
Relations
BioProject PRJNA400561
SRA SRP116376

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE103220_gene_list_of_WT_and_RBP-J_KO.txt.gz 12.4 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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