|
| Status |
Public on Jun 26, 2018 |
| Title |
RNA sequencing of Foxd1Cre;Smo(flox/-) mutant kidneys |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Purpose: To analyze the mRNA content of Foxd1Cre;Smo(flox/-) mutant kidneys.
Methods: We collected E13.5 wildtype and Foxd1Cre;Smo(flox/-) mutant kidneys and isolated RNA to do RNA-Seq.
Results: Identified differentially expressed transcripts in Foxd1Cre;Smo(flox/-) mutant kidneys compared to wildtype controls.
Conclusions: Our work provides novel insight into how Hedgehog signaling from stromal cells influences renal development.
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| |
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| Overall design |
RNA sequencing of Foxd1Cre;Smo(flox/-) mutant kidneys compared to controls.
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| |
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| Contributor(s) |
Rosenblum ND, Rowan CJ, Li W |
| Citation(s) |
29945868 |
| |
| Submission date |
Sep 15, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Norman D Rosenblum |
| E-mail(s) |
norman.rosenblum@sickkids.ca
|
| Organization name |
The Hospital for Sick Children
|
| Street address |
686 Bay Street
|
| City |
Toronto |
| ZIP/Postal code |
M5G0A4 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (8)
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| Relations |
| BioProject |
PRJNA407570 |
| SRA |
SRP117757 |
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