|
Status |
Public on Aug 30, 2018 |
Title |
Paternal exposure to Arctic contaminants alters the sperm epigenome and induces negative pregnancy outcomes transgenerationally |
Organism |
Rattus norvegicus |
Experiment type |
Methylation profiling by high throughput sequencing
|
Summary |
Paternal exposure to environmentally-relevant Arctic contaminants induces adverse health outcomes and alters the sperm methylome over three generations.
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|
|
Overall design |
Genome-wide methylation profiles of rat epididymal sperm across F1, F2 and F3 generations spermatozoa profiles (6 organochlorines exposed and 6 controls per generation)
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|
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Contributor(s) |
Bailey JL |
Citation(s) |
29750268, 34968297 |
|
Submission date |
Jan 10, 2018 |
Last update date |
Jan 10, 2022 |
Contact name |
Clémence Belleannee |
Organization name |
CHU de Québec-Université Laval Research Center
|
Street address |
2705 Bd Laurier
|
City |
Québec |
ZIP/Postal code |
G1V 4G2 |
Country |
Canada |
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|
Platforms (1) |
GPL14844 |
Illumina HiSeq 2000 (Rattus norvegicus) |
|
Samples (48)
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|
Relations |
BioProject |
PRJNA429491 |
SRA |
SRP128759 |