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| Status |
Public on Aug 02, 2018 |
| Title |
Characterization of genome-wide DNA binding rhythms of HNF4A |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
HNF4A mRNA cycles over the coure of 24 h. To understand whether the chromatin binding of the transcription factor is also rhythmic, we performed ChIP-seq for HNF4A using mouse liver samples of ZT4 and ZT16. By analysing this dataset, we conclude that HNF4A binds chromatin much more robustly during the evening ( at ZT16).
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| Overall design |
Examination of HNF4A genome binding at ZT4 and ZT16 using mouse liver samples, three mice were tested for each time point
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| |
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| Contributor(s) |
Qu M, Kay S |
| Citation(s) |
30530698 |
| |
| Submission date |
Aug 01, 2018 |
| Last update date |
May 16, 2019 |
| Contact name |
Meng Qu |
| E-mail(s) |
marciaqu@gmail.com
|
| Phone |
626-898-2391
|
| Organization name |
University of Southern California
|
| Department |
Keck Medical School
|
| Lab |
Steve Kay lab
|
| Street address |
1002 West Childs Way
|
| City |
Los Angeles |
| State/province |
California |
| ZIP/Postal code |
90089 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA483995 |
| SRA |
SRP156003 |
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