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| Status |
Public on Nov 27, 2019 |
| Title |
Transcriptomic profiling of nasopharyngeal carcinoma (NPC) and normal control samples |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To understand the genes and pathways that may potentially drive nasopharyngeal carcinoma (NPC) pathogenesis, we sought out to analyze the transcriptomic data from the disease and control samples. We used RNA-sequencing based gene expression data to identify genes differentially expressed between NPC and normal controls and then characterize the gene ontology and pathways down- or up-regulated in the disease samples.
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| Overall design |
7 NPC biopsy specimens and 4 normal nasopharyngeal mucosal specimens were sampled. Total RNA were extracted from these samples, and analyzed by RNA-sequencing.
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| Contributor(s) |
Lin C, Zong J, Lin W, Wang M, Xu Y, Zhou R, Lin S, Guo Q, Chen H, Ye Y, Zhang B, Pan J |
| Citation(s) |
30477559 |
| |
| Submission date |
Aug 17, 2018 |
| Last update date |
Nov 27, 2019 |
| Contact name |
Bin Zhang |
| Organization name |
Icahn School of Medicine at Mount Sinai
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| Department |
Genetics and Genomic Sciences
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| Street address |
1470 Madison Avenue
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| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10029 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (11)
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| This SubSeries is part of SuperSeries: |
| GSE118721 |
Transcriptomic profiling of mRNA and miRNA from nasopharyngeal carcinoma (NPC) and normal control samples |
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| Relations |
| BioProject |
PRJNA486533 |
| SRA |
SRP158280 |
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