|
| Status |
Public on Aug 21, 2019 |
| Title |
Transcriptomic analysis of the Csr system in Erwinia amylovora |
| Organism |
Erwinia amylovora |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This RNA-seq analysis examined the global effect of CsrA and its non-coding small RNA (ncsRNA) csrB in E. amylovora under the T3SS-inducing condition. The csrA mutant showed differential expression of more than 20% genes in the genome, which include significant down-regulation of T3SS genes and those required for cell growth and viability. On the other hand, the csrB mutant exhibited significant up-regulation of most major virulence genes, suggesting antagonistic effect of csrB on CsrA targets.
|
| |
|
| Overall design |
Differential gene expression of the csrA and csrB mutants versus wild type grown in the T3SS-inducing condition for 6 hours
|
| |
|
| Contributor(s) |
Lee JH, Chatnaparat T, Zhao Y |
| Citation(s) |
31140921, 32228459 |
| |
| Submission date |
Mar 11, 2019 |
| Last update date |
Apr 06, 2020 |
| Contact name |
Frank Zhao |
| E-mail(s) |
frankzhao55@gmail.com
|
| Phone |
2172659822
|
| Organization name |
University of Illinois
|
| Department |
Crop Sciences
|
| Street address |
1201 W. Gregory Dr.
|
| City |
Urbana |
| State/province |
IL |
| ZIP/Postal code |
61801 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL26279 |
Illumina HiSeq 2500 (Erwinia amylovora) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA526429 |
| SRA |
SRP188070 |
Less...
More...