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| Status |
Public on Sep 15, 2020 |
| Title |
Expression data of primary murine liver sinusoidal endothelial cells after 10 weeks of CDAA diet |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Liver sinusoidal endothelial cells (LSEC) constitute discontinuous, permeable microvessels, with a characteristic program of gene expression that differs significantly from continuous microvascular endothelial cells e.g. in the lung. LSEC play a pivotal role in liver fibrogenesis in the CDAA dietary model of non-alcoholic steatohepatitis (NASH).
We used microarrays to analyse the program of gene expression in murine liver endothelial cells after 10 weeks of CDAA diet.
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| Overall design |
Murine liver sinusoidal endothelial cells (mLSEC) of Gata4 endothelial cell-subtype specific knockout (Gata4-LSEC-KO) and sibling control mice were isolated for RNA extraction and hybridization on Affymetrix microarrays.
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| Contributor(s) |
Winkler M, Sticht C |
| Citation(s) |
32916216 |
| |
| Submission date |
Nov 25, 2019 |
| Last update date |
Oct 21, 2020 |
| Contact name |
Carsten Sticht |
| Organization name |
University Heidelberg
|
| Department |
ZMF
|
| Street address |
Theodor-Kutzer-Ufer
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| City |
Mannheim |
| ZIP/Postal code |
68169 |
| Country |
Germany |
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| Platforms (1) |
| GPL24557 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [CDF: mogene20st_Mm_ENTREZG_22] |
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| Samples (10)
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| This SubSeries is part of SuperSeries: |
| GSE141004 |
Expression data of murine liver sinusoidal endothelial cells |
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| Relations |
| BioProject |
PRJNA591629 |
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