|
| Status |
Public on May 02, 2021 |
| Title |
Infection of rat epithelial cells with a Salmonella typhimurium strain expressing Rck, PagN and the T3SS1 system (14028Sur) and two Salmonella typhimurium strains invalidated for entry factors (i.e. D(rck, pagN) and DinvASur) |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
The aim of this work was to study the cellular gene expression profiles associated with the entry mechanism of Salmonella typhimurium. Whatever the bacterial strain used for infection, the expression of numerous genes associated with the extracellular matrix was modified.
|
| |
|
| Overall design |
Six biological replicates for non-infected cells, six for the cells infected with the DinvASur and the 14028Sur strains and five biological replicates for the cells infected with the D(rck, pagN) strain.
|
| |
|
| Contributor(s) |
Chaussé AM, Roche S, Moroldo M, Velge P |
| Citation(s) |
36600181 |
| |
| Submission date |
Jun 05, 2020 |
| Last update date |
Jan 25, 2023 |
| Contact name |
Marco Moroldo |
| E-mail(s) |
marco.moroldo@inrae.fr
|
| Organization name |
INRA
|
| Department |
Animal Genetics
|
| Lab |
GIBBS
|
| Street address |
Domaine de Vilvert
|
| City |
Jouy-en-Josas |
| ZIP/Postal code |
78352 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL22145 |
Agilent-074036 SurePrint G3 Rat GE v2 8x60K Microarray G4858A (Feature Number version) |
|
| Samples (23)
|
| GSM4592644 |
cell_Salmonella_expressing_Rck_PagN_invalidated_T3SS1_1 |
| GSM4592645 |
cell_Non_infected_1 |
| GSM4592646 |
cell_Salmonella_expressing_Rck_PagN_T3SS1_1 |
| GSM4592647 |
cell_Salmonella_invalidated_Rck_PagN_1 |
| GSM4592648 |
cell_Non_infected_2 |
| GSM4592649 |
cell_Salmonella_expressing_Rck_PagN_invalidated_T3SS1_2 |
| GSM4592650 |
cell_Salmonella_invalidated_Rck_PagN_2 |
| GSM4592651 |
cell_Salmonella_expressing_Rck_PagN_T3SS1_2 |
| GSM4592652 |
cell_Salmonella_invalidated_Rck_PagN_3 |
| GSM4592653 |
cell_Non_infected_3 |
| GSM4592654 |
cell_Salmonella_expressing_Rck_PagN_T3SS1_3 |
| GSM4592655 |
cell_Salmonella_expressing_Rck_PagN_invalidated_T3SS1_3 |
| GSM4592656 |
cell_Non_infected_4 |
| GSM4592657 |
cell_Salmonella_invalidated_Rck_PagN_4 |
| GSM4592658 |
cell_Salmonella_expressing_Rck_PagN_invalidated_T3SS1_4 |
| GSM4592659 |
cell_Salmonella_expressing_Rck_PagN_T3SS1_4 |
| GSM4592660 |
cell_Non_infected_5 |
| GSM4592661 |
cell_Salmonella_invalidated_Rck_PagN_5 |
| GSM4592662 |
cell_Salmonella_expressing_Rck_PagN_invalidated_T3SS1_5 |
| GSM4592663 |
cell_Salmonella_expressing_Rck_PagN_T3SS1_5 |
| GSM4592664 |
cell_Non_infected_6 |
| GSM4592665 |
cell_Salmonella_expressing_Rck_PagN_T3SS1_6 |
| GSM4592666 |
cell_Salmonella_expressing_Rck_PagN_invalidated_T3SS1_6 |
|
| Relations |
| BioProject |
PRJNA637581 |
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