|
| Status |
Public on Mar 17, 2021 |
| Title |
Extended archaeal histone-based chromatin structure regulates global gene expression in Thermococcus kodakarensis |
| Organism |
Thermococcus kodakarensis |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Using the model organism Thermococcus kodakarensis, we genetically alter the chromatin landscape and quantify the resultant changes in gene expression, including unanticipated and significant impacts on provirus transcription. Global transcriptome changes resultant from varying chromatin landscapes reveal the regulatory importance of higher-order histone-based chromatin architectures in regulating gene expression.
|
| |
|
| Overall design |
Examination of 3 variant chromatin structures on gene expression
|
| |
|
| Contributor(s) |
Sanders TJ, Ullah F, Gehring AM, Burkhart BW, Vickerman R, Fernando S, Gardner AF, Ben-Hur A, Santangelo TJ |
| Citation(s) |
34054788 |
| |
| Submission date |
Jun 05, 2020 |
| Last update date |
Jun 03, 2021 |
| Contact name |
Thomas Santangelo |
| E-mail(s) |
thomas.santangelo@colostate.edu
|
| Organization name |
Colorado State University
|
| Street address |
1062 Campus Delivery
|
| City |
Fort Collins |
| ZIP/Postal code |
80523 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL27055 |
Illumina NextSeq 500 (Thermococcus kodakarensis) |
| GPL28639 |
Illumina HiSeq 4000 (Thermococcus kodakarensis) |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA637645 |
| SRA |
SRP266191 |
Less...
More...