|
| Status |
Public on Sep 30, 2020 |
| Title |
Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB signaling in triple negative breast cancer [RNA-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The purpose of this study was to elucidate the transcriptome of ERβ expressing MDA-MB-231 cells following treatment with veh, E2, TNFα, or E2+TNFα.
|
| |
|
| Overall design |
ERβ-expressing MDA-MB-231 cells were treated with ethanol vehicle or 1nM E2 for 5 days, followed by 3 hours of 20ng/ml TNFα in replicates of 3.
|
| |
|
| Contributor(s) |
Aspros KG, Hawse JR |
| Citation(s) |
35177654 |
| |
| Submission date |
Aug 04, 2020 |
| Last update date |
Mar 09, 2022 |
| Contact name |
Aditya Bhagwate |
| E-mail(s) |
bhagwate.adityavijay@mayo.edu
|
| Organization name |
Mayo Clinic
|
| Street address |
200 1st Street SW
|
| City |
Rochester |
| State/province |
MN |
| ZIP/Postal code |
55905 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (12)
|
|
| This SubSeries is part of SuperSeries: |
| GSE155686 |
Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB signaling in triple negative breast cancer |
|
| Relations |
| BioProject |
PRJNA655221 |
| SRA |
SRP275827 |
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