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| Status |
Public on Mar 16, 2021 |
| Title |
Transcriptome RNA Sequencing Data Set of Differential Gene Expression in Escherichia Coli BW25113 SlyA Wild Type and Mutant Strains |
| Organism |
Escherichia coli |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Escherichia coli laboratory strains remain instrumental to the discovery and development of biomarkers as drugs and diagnostic analytes in the post genomic era. The transcriptional regulator SlyA is a member of the multiple antibiotic resistance regulator family of transcription factors, which is associated with bacterial responses to host-derived oxidative stress, antibiotics resistance and virulence, and homologues exist in other Enterobacteriaceae. Here, we announce a transcriptome RNA sequencing data set detailing global gene expression in the wild type E. coli BW25113 and the slyA mutant. Results reveal heterogeneous functionality of SlyA that may vary between pathovars of E. coli. but which require further annotations of differentially expressed tRNAs
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| |
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| Overall design |
Examination of Gene expresison profiles of SlyA mutant and WT strains of Escherichia Coli BW25113
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| |
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| Contributor(s) |
Ojo O, Scott D, Odetoyin B, Iwalokun B, Grove A |
| Citation(s) |
33986090 |
| |
| Submission date |
Mar 15, 2021 |
| Last update date |
Jun 28, 2021 |
| Contact name |
Derrick Scott |
| Organization name |
Delaware State University
|
| Street address |
1200 n dupont hwy
|
| City |
dover |
| State/province |
Delaware |
| ZIP/Postal code |
19901 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL21222 |
Illumina NextSeq 500 (Escherichia coli) |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA714667 |
| SRA |
SRP310752 |
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