|
| Status |
Public on May 12, 2022 |
| Title |
Transcriptome profiling of muscle from control, mdx and Sirt6 knockout on mdx background mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
In this study, Pax7-Cre mediated inactivation of Sirt6 in mdx mice resulted in profound improvement of the mdx phenotype at the functional level. To study the underlying molecular mechanisms we performed RNA-seq of muscles from control, mdx and Sirt6mKO/mdx mice.
|
| |
|
| Overall design |
RNA-seq analysis of muscle from control (wild type), mdx and Sirt6mKO/mdx mice
|
| |
|
| Contributor(s) |
Georgieva AM, Günther S, Kuenne C |
| Citation(s) |
35859073 |
| |
| Submission date |
Mar 16, 2021 |
| Last update date |
Aug 03, 2022 |
| Contact name |
Carsten Kuenne |
| E-mail(s) |
Carsten.Kuenne@mpi-bn.mpg.de
|
| Organization name |
Max Planck Institute for Heart and Lung Research
|
| Department |
Bioinformatics
|
| Street address |
Ludwigstrasse 43
|
| City |
Bad Nauheim |
| ZIP/Postal code |
61231 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA714834 |
| SRA |
SRP310850 |
Less...
More...