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| Status |
Public on May 18, 2022 |
| Title |
Genome-wide maps of FOXK2 binding sites in ovarian cancer cell line OVCAR5 and expression profile of FOXK2 knockdown OVCAR5 cells (ChIP-seq) |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
This study characterized the genome-wide binding of FOXK2 in ovarian cancer (OC) cell OVCAR-5 and investigated the expression profile of OVCAR5 cells with FOXK2 knocking-down.
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| Overall design |
Two datasets are included: 1) Examined transcriptome of OVCAR5 cells transduced with control shRNA (shCtrl) and FOXK2-targeting shRNA (shFOXK2) in OVCAR5 cells (in biological duplicates); 2) Determined the genome-wide bindng and occupancy profile of FOXK2 in OVCAR5 cells by ChIP-seq (in biological duplicates).
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| |
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| Contributor(s) |
Zhang Y, Wang Y, Zhao G, Matei D |
| Citation(s) |
35349489 |
| |
| Submission date |
May 03, 2021 |
| Last update date |
May 20, 2022 |
| Contact name |
Daniela Matei |
| E-mail(s) |
daniela.matei@northwestern.edu
|
| Organization name |
Northwestern University
|
| Department |
Ob-Gyn
|
| Street address |
303 E Superior St
|
| City |
Chicago |
| State/province |
Illinois |
| ZIP/Postal code |
60601 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE173780 |
Genome-wide maps of FOXK2 binding sites in ovarian cancer cell line OVCAR5 and expression profile of FOXK2 knockdown OVCAR5 cells |
|
| Relations |
| BioProject |
PRJNA727006 |
| SRA |
SRP318249 |
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