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| Status |
Public on Jul 15, 2021 |
| Title |
Functional and Structural Segregation of Overlapping Helices in HIV-1 |
| Organism |
Human immunodeficiency virus 1 |
| Experiment type |
Other
|
| Summary |
We report deep mutational scanning data for the Env protein's LLP-2 domain in the NL4-3 strain HIV-1 Env. Processed Data repersents counts for each amino acid pre and post spread
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| |
|
| Overall design |
Each fastq file represents either a pre or post-selection virus in which a single codon of the Env LLP-2 has been randomized to NNN. Pre-selection (Inputs) are roughly randomly spread out amongst all 64 codons, while post selection viruses represent only amino acids that are viable in a spreading assay.
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| |
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| Contributor(s) |
Fernandes JD |
| Citation(s) |
35511220 |
| |
| Submission date |
Jun 28, 2021 |
| Last update date |
May 26, 2022 |
| Contact name |
Jason Fernandes |
| E-mail(s) |
jason.d.fernandes@gmail.com
|
| Organization name |
UCSF
|
| Street address |
600 16th Street, Genentech Hall, Room S574, MC 2280
|
| City |
San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94158 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL23868 |
Illumina MiSeq (Human immunodeficiency virus 1) |
|
| Samples (76)
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| Relations |
| BioProject |
PRJNA742013 |
| SRA |
SRP325862 |
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