|
| Status |
Public on Sep 26, 2021 |
| Title |
CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity [scRNA-seq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Integrative system approaches uncover a three-tier system for the regulatory modules of nutrient signaling-dependent mTORC1 activation in regulatory T cells
|
| |
|
| Overall design |
We used scRNA-seq to profile CD45+YFP+ Treg cells, CD45+YFP-CD11b- non-Treg cells and CD45+CD11b+ myeloid cells (mixed at 1:2:1 ratio) in the MC38 colon adenocarcinoma
|
| |
|
| Contributor(s) |
Shi H, Long L, Chi H |
| Citation(s) |
34795452 |
| |
| Submission date |
Aug 02, 2021 |
| Last update date |
Nov 24, 2021 |
| Contact name |
Hongbo Chi |
| E-mail(s) |
hongbo.chi@stjude.org
|
| Organization name |
St Jude Children's Research Hospital
|
| Department |
Immunology
|
| Street address |
262 Danny Thomas Place
|
| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38105 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
|
| Samples (4)
|
|
| This SubSeries is part of SuperSeries: |
| GSE160598 |
CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity |
|
| Relations |
| BioProject |
PRJNA751600 |
| SRA |
SRP330912 |
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