|
| Status |
Public on Mar 04, 2022 |
| Title |
Regulation of Chromatin Accessibility by hypoxia and HIF_1 |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
ATAC-seq was performed to investigate changes in chromatin accessibility in repsonse to hypoxia
|
| |
|
| Overall design |
HeLa cells were grown at 21% oxygen, treated with control and HIF1B siRNA and exposed to 1% oxygen (hypoxia) for 0, 1 and 24 hs. HeLa cells were also grown at 21% oxygen, treated with control siRNA and exposed to 1% oxygen for 24 hs followed by reoxygenation at 21% oxygen for 1 h. ATAC-seq was used to determine chromatin accessibility changes.
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| |
|
| Contributor(s) |
Batie M, Rocha S |
| Citation(s) |
35258521 |
| |
| Submission date |
Oct 21, 2021 |
| Last update date |
Jun 04, 2022 |
| Contact name |
Sonia Rocha |
| E-mail(s) |
sonia.rocha@liverpool.ac.uk
|
| Organization name |
University of Liverool
|
| Street address |
Crown Street
|
| City |
Liverpool |
| ZIP/Postal code |
L69 7ZB |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (14)
|
|
| Relations |
| BioProject |
PRJNA773425 |
| SRA |
SRP342583 |
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