|
| Status |
Public on Jul 06, 2010 |
| Title |
ChIP-chip from different B cell stages with Abs to H3K4me3, H3K4me1, H3K9,K14-diacetyl, H3K27me3 and RNA polymerase II |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by genome tiling array
|
| Summary |
B cell differentiation stage specific histone modifications detected within and upstream of genes that play critical roles in B cell differentation.
Germinal center B cell stage specific activating histone marks in regions far upstream of the BCL6 promoter regulate BCL6 expression.
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| |
|
| Overall design |
comparison of histone modifications of genes having a role in B cell differentiation in human primary tonsillar naïve B-cells and germinal center B-cells and in CL01, SUDHL16 and U266 cell lines.
|
| |
|
| Contributor(s) |
Ramachandrareddy H, Chan WC, McKeithan TW |
| Citation(s) |
20547840 |
| |
| Submission date |
Jan 15, 2010 |
| Last update date |
Mar 21, 2012 |
| Contact name |
Himabindu Ramachandrareddy |
| E-mail(s) |
hramacha@unmc.edu
|
| Phone |
402-559-7921
|
| Organization name |
University of Nebraska Medical Center
|
| Department |
Pathology and microbiology
|
| Lab |
Leukaemia and Lymphoma research
|
| Street address |
600 South 42nd st
|
| City |
Omaha |
| State/province |
NE |
| ZIP/Postal code |
68198 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL9924 |
NimbleGen Human 385 K array V1.0 |
|
| Samples (23)
|
| GSM497592 |
Centroblasts H3K9,K14-diacetylated |
| GSM497593 |
CL01 cell line H3K9,K14-diacetylated |
| GSM497594 |
SUDHL16 cell line H3K9,K14-diacetylated |
|
| Relations |
| BioProject |
PRJNA121943 |
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