|
| Status |
Public on Jan 03, 2023 |
| Title |
Transit-amplifying lineage states convey the susceptibility of PTEN and P53 loss to gliomagenesis [ATAC-seq] |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
To investigate the glioma mouse model by knocking out Pten and Trp53 in embryonal Olig2 and Olig1 positive cells in glioma pathogenesis.
ATAC-seq
|
| |
|
| Overall design |
Total 2 samples were analyzed of 1 each of PPO1 and PPO2 cell line
|
| |
|
| Contributor(s) |
Lu QR, Verma RK, Xin D |
| Citation(s) |
36634201 |
| |
| Submission date |
Apr 15, 2022 |
| Last update date |
Jun 29, 2023 |
| Contact name |
Richard Q. Lu |
| E-mail(s) |
richard.lu@cchmc.org, vermare@mail.uc.edu
|
| Phone |
15133941514
|
| Organization name |
Cincinnati Childrens Hosp Med Ctrl
|
| Department |
CBDI
|
| Lab |
Lu Lab, T6 525
|
| Street address |
3333 Burnet Avenue
|
| City |
CINCINNATI |
| State/province |
OH |
| ZIP/Postal code |
45229 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (2) |
|
| This SubSeries is part of SuperSeries: |
| GSE200892 |
Olig1/2-expressing intermediate lineage progenitors are predisposed to PTEN/p53-loss-induced gliomagenesis and harbor specific therapeutic vulnerabilities |
|
| Relations |
| BioProject |
PRJNA827148 |
