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| Status |
Public on Nov 29, 2022 |
| Title |
Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodium falciparum |
| Organisms |
Plasmodium falciparum; Plasmodium falciparum NF54 |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
RNAseq data profiling the artemisinin-sensitive P. falciparum piggyBac mutant of the KIC5 gene (PF3D7_1138700, Kelch13 Interacting Candidate 5).
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| Overall design |
Paired-end fastq data for two complete bioreps of the two parasite lines (NF54 wild-type control; artemisinin-sensitive mutant referred to in sample-names as PB50) collected after 3 rounds of sorbitol synchronization under normal asexual growth conditions. Parasites were at early ring stage (T6), mid ring stage (T12), early trophozoite stage (T24), late trophozoite stage (T36), or schizont stage (T48) as verified by Giemsa-stained microscopy. Each sample was run on an Illumina Nextseq.
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| Contributor(s) |
Simmons C, Gibbons J, Zhang M, Oberstaller J, Pires CV, Wang C, Xu S, Casandra D, Seyfang A, Otto TD, Rayner JC, Adams JH |
| Citation(s) |
36624300 |
| |
| Submission date |
May 27, 2022 |
| Last update date |
Jan 25, 2023 |
| Contact name |
Caroline Simmons |
| Organization name |
University of South Florida
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| Department |
Center for Global Health and Infectious Diseases Research
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| Lab |
John Adams Laboratory
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| Street address |
3720 East Spectrum Blvd St. 404
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| City |
Tampa |
| State/province |
FL |
| ZIP/Postal code |
33620 |
| Country |
USA |
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| Platforms (2) |
| GPL21298 |
Illumina NextSeq 500 (Plasmodium falciparum) |
| GPL23997 |
Illumina NextSeq 500 (Plasmodium falciparum NF54) |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA843072 |
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