 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Aug 20, 2022 |
| Title |
Myeloid-derived Itaconate Suppresses Cytotoxic CD8+ 1 T Cells and Promotes Tumor Growth |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate the effect of itaconate on CD4+ T cells, we treated the purified splenic CD4+ T cells with NaCl or itaconate, and then performed the gene expression profilling analysis using data from RNA-seq of 2 different treatment cells.
|
| |
|
| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for NaCl (Ctrl) or itaconate (ITA) treatment of mouse splenic CD4+ T cells
|
| |
|
| Contributor(s) |
Teng D, Jiang T, Gu L |
| Citation(s) |
36376563 |
| Submission date |
Aug 15, 2022 |
| Last update date |
Nov 15, 2022 |
| Contact name |
Da Teng |
| E-mail(s) |
DTENG@mgh.harvard.edu
|
| Organization name |
Massachusetts General Hospital
|
| Street address |
Building 149, 13th Street
|
| City |
Charlestown |
| State/province |
MA |
| ZIP/Postal code |
02129 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA869690 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE211255_CD4ITA_CD4WT_RSEM_normalized_count_for_GSEA.txt.gz |
965.2 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
|
|
|
|
 |
Less...
More...