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| Status |
Public on Sep 10, 2022 |
| Title |
Multiomic Analysis of Adult Diapause in Drosophila melanogaster Identifies Hallmarks of Cellular Quiescence [ATAC-seq] |
| Organism |
Drosophila melanogaster |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Diapause and diapause-like states constitute natural, inducible, and evolutionarily conserved examples of lifespan plasticity that are well-suited to represent physiologically accurate models for longevity. We integrated ATAC-seq and RNA-seq technologies to probe the transcriptional regulatory pathways controlling lifespan plasticity in diapause.
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| Overall design |
Comparison of chromatin accessibility profiles from w1118 virgin female adult Drosophila in diapause or in regular conditions, additionally supplemented with either S-methoprene or ethanol (vehicle) for a total of 4 experimental conditions.
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| Contributor(s) |
Corinne H |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Sep 07, 2022 |
| Last update date |
Dec 21, 2022 |
| Contact name |
Corinne Hutfilz |
| E-mail(s) |
chutfilz@gmail.com
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| Organization name |
Brown University
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| Street address |
171 Meeting St.
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| City |
Providence |
| State/province |
Rhode Island |
| ZIP/Postal code |
02912 |
| Country |
USA |
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| Platforms (1) |
| GPL23702 |
HiSeq X Ten (Drosophila melanogaster) |
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| Samples (16)
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| GSM6559819 |
11, S-methoprene, rep1 |
| GSM6559820 |
25, EtOH, rep2 |
| GSM6559821 |
25, S-methoprene, rep2 |
| GSM6559822 |
11, EtOH, rep2 |
| GSM6559823 |
11, S-methoprene, rep2 |
| GSM6559824 |
25, EtOH, rep3 |
| GSM6559825 |
25, S-methoprene, rep3 |
| GSM6559826 |
11, EtOH, rep3 |
| GSM6559827 |
11, S-methoprene, rep3 |
| GSM6559828 |
25, EtOH, rep4 |
| GSM6559829 |
25, S-methoprene, rep4 |
| GSM6559830 |
11, EtOH, rep4 |
| GSM6559831 |
11, S-methoprene, rep4 |
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| This SubSeries is part of SuperSeries: |
| GSE212864 |
Multiomic Analysis of Adult Diapause in Drosophila melanogaster Identifies Hallmarks of Cellular Quiescence |
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| Relations |
| BioProject |
PRJNA877666 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE212862_DiffBindresults_temp_axis.csv.gz |
479.7 Kb |
(ftp)(http) |
CSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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