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| Status |
Public on Apr 28, 2023 |
| Title |
Age-associated DNA methylation changes in Xenopus frogs |
| Organism |
Xenopus tropicalis |
| Experiment type |
Methylation profiling by high throughput sequencing
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| Summary |
Here we present clear patterns of age-associated changes in DNA methylation in the aquatic vetebrate species Xenopus tropicalis. We generated nine whole-genome bisulfite sequencing (WGBS) datasets from three distinct age groups (young, approx. 1 year old; mature, approx. 5 years old; old, approx. 9 years old) to characterize the gene- and chromosome-scale changes.
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| Overall design |
We have generated whole genome bisulfite sequencing (WGBS) profiles in nine Xenopus tropicalis samples representing young, mature and old adults to study how DNA methylation relates to aging in frogs.
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| Web link |
https://www.tandfonline.com/doi/full/10.1080/15592294.2023.2201517
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| |
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| Contributor(s) |
Morselli M, Bennett R, Shaidani N, Horb M, Peshkin L, Pellegrini M |
| Citation(s) |
37092296 |
| |
| Submission date |
Dec 23, 2022 |
| Last update date |
May 24, 2023 |
| Contact name |
Marco Morselli |
| E-mail(s) |
marco.morselli@unipr.it
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| Organization name |
University of Parma
|
| Department |
S.C.V.S.A.
|
| Street address |
Parco Area delle Scienze, 23/A
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| City |
Parma |
| State/province |
Parma |
| ZIP/Postal code |
43124 |
| Country |
Italy |
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| Platforms (1) |
| GPL30018 |
Illumina NovaSeq 6000 (Xenopus tropicalis) |
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| Samples (9)
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| This SubSeries is part of SuperSeries: |
| GSE222108 |
Age-associated DNA methylation changes in Xenopus frogs, and Targeted bisulfite sequencing to profile age-associated DNA methylation changes in Xenopus frogs |
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| Relations |
| BioProject |
PRJNA915337 |
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