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| Status |
Public on Jun 20, 2023 |
| Title |
Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Female Wistar rats were either fed nutrient source-matched control diet (control) or a high fat diet (HFD). HFD-fed rats presented with increased ICP, which was not accompanied by altered CSF dynamics or modified choroid plexus function. HFD-induced ICP elevation in experimental rats did not originate from an increased rate of CSF secretion.
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| Overall design |
Differential expression analysis of female wistar rats fed either nutrient source-matched control diet (control) or high fat diet (HFD).
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| Web link |
https://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-023-00436-1
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| |
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| Contributor(s) |
Andreassen SN, Wardman JH, MacAulay N |
| Citation(s) |
37328884 |
| |
| Submission date |
Jan 24, 2023 |
| Last update date |
Jun 23, 2023 |
| Contact name |
Søren Norge Andreassen |
| E-mail(s) |
snorge@sund.ku.dk
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| Organization name |
University of Copenhagen
|
| Department |
Department of Neuroscience
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| Lab |
MacAulay
|
| Street address |
Blegdamsvej 3
|
| City |
Copenhagen |
| State/province |
Region Hovedstaden |
| ZIP/Postal code |
2200 |
| Country |
Denmark |
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| Platforms (1) |
| GPL25947 |
Illumina NovaSeq 6000 (Rattus norvegicus) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA926919 |
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