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| Status |
Public on Jul 01, 2010 |
| Title |
Analysis of gene expression in different T cell clones |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
The aim was to analyze the expression of genes in Th17 cell clones derived from a patient affected by multiple sclerosis before and after activation with anti-CD3 and anti-CD28.
Keywords: Gene expression, T cell clones, Th17 characterisation
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| Overall design |
The T cell clones were derived according to well known protocol, using different cytokines, and classified on the basis of their ability to produce cytokines. Once characterized for their production of different cytokines, they were stimulated with anti-CD23 and anti-CD28 and used to prepare microarray experiments comparing the stimulated clones against the unstimulated ones.
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| Contributor(s) |
Rodolico G, Cosmi L, Annunziato F, De Palma R |
| Citation(s) |
22219326 |
| |
| Submission date |
Jun 30, 2010 |
| Last update date |
Jan 18, 2013 |
| Contact name |
gabriella rodolico |
| E-mail(s) |
rodgab@email.it
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| Organization name |
Second University of Naples
|
| Street address |
Via Costantinopoli 16
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| City |
Naples |
| ZIP/Postal code |
80138 |
| Country |
Italy |
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| Platforms (1) |
| GPL3307 |
ABI Human Genome Survey Microarray v2.0 |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA128039 |
