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GEO help: Mouse over screen elements for information. |
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| Status |
Public on May 12, 2023 |
| Title |
PolyA RNA-seq from liposarcoma cells treated with Nutlin3R and/or Carfilzomib |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Analysis of steady-state mRNA levels in liposarcoma cells treated for 28 hr with 0.05% DMSO or 10 uM Nutlin3R and/or 12.5 nM Carfilzomib
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| Overall design |
Two independent biological replicates each of 94T778 and Lipo-246 cells, treated for 28 hr with 0.05% DMSO or 10 uM Nutlin3R and/or 12.5 nM Carfilzomib
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| Contributor(s) |
Ludwig MP, Sullivan KD, Galbraith MD, Espinosa JM |
| Citation(s) |
37205634 |
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| Submission date |
Mar 02, 2023 |
| Last update date |
Aug 11, 2023 |
| Contact name |
Matthew D Galbraith |
| Organization name |
University of Colorado Anschutz Medical Campus
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| Department |
Pharmacology & Linda Crnic Institute for Down Syndrome
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| Street address |
RC1-N, Mail Stop 8303, Rm. P18-6114 12800 E. 19th Ave.
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| City |
Aurora |
| State/province |
CO |
| ZIP/Postal code |
80045 |
| Country |
USA |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (16)
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| GSM7078428 |
94T778, 10uM Nutlin 28hr, replicate 2 |
| GSM7078429 |
94T778, 12.5nM Carfilzomib 28hr, replicate 1 |
| GSM7078430 |
94T778, 12.5nM Carfilzomib 28hr, replicate 2 |
| GSM7078431 |
94T778, 10uM Nutlin, 12.5nM Carfilzomib 28hr, Combo replicate 1 |
| GSM7078432 |
94T778, 10uM Nutlin, 12.5nM Carfilzomib 28hr, Combo replicate 2 |
| GSM7078433 |
Lipo-246, DMSO, replicate 1 |
| GSM7078434 |
Lipo-246, DMSO, replicate 2 |
| GSM7078435 |
Lipo-246, 10uM Nutlin 28hr, replicate 1 |
| GSM7078436 |
Lipo-246, 10uM Nutlin 28hr, replicate 2 |
| GSM7078437 |
Lipo-246, 12.5nM Carfilzomib 28hr, replicate 1 |
| GSM7078438 |
Lipo-246, 12.5nM Carfilzomib 28hr, replicate 2 |
| GSM7078439 |
Lipo-246, 10uM Nutlin, 12.5nM Carfilzomib 28hr, Combo replicate 1 |
| GSM7078440 |
Lipo-246, 10uM Nutlin, 12.5nM Carfilzomib 28hr, Combo replicate 2 |
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| This SubSeries is part of SuperSeries: |
| GSE214891 |
Proteasome Inhibition Sensitizes Liposarcoma to Nutlin-3-induced Apoptosis via the ATF4/CHOP Axis |
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| Relations |
| BioProject |
PRJNA940486 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE226530_LPS3_94T_Lipo246_Gencodev33_RPKMs_for_GEO.txt.gz |
3.5 Mb |
(ftp)(http) |
TXT |
| GSE226530_LPS3_94T_Lipo246_Gencodev33_counts_for_GEO.txt.gz |
830.2 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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