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| Status |
Public on May 05, 2023 |
| Title |
Histone H3/H4 chaperone CHAF1B prevents the mislocalization of CENP-A for chromosomal stability |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Mislocalization of CENP-A to non-centromeric regions contributes to chromosomal instability (CIN). Here, we defined a role for the histone H3/H4 chaperone CHAF1B in preventing mislocalization of CENP-A and CIN.
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| Overall design |
CUT&RUN for CENP-A, n=1 of 2 antibodies
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| Contributor(s) |
Shrestha R, Balachandra V, Kim JH, Rossi A, Vadlamani P, Ozbun L, Lin S, Cheng K, Chari R, Pegoraro G, Foltz DR, Caplen NJ, Basrai MA |
| Citation(s) |
37129573 |
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| Submission date |
Mar 14, 2023 |
| Last update date |
Aug 07, 2023 |
| Contact name |
Daniel Foltz |
| Organization name |
Northwestern University
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| Street address |
303 E Superior St
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| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60611 |
| Country |
USA |
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| Platforms (1) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA944730 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE227373_RAW.tar |
1.1 Gb |
(http)(custom) |
TAR (of BW) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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