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| Status |
Public on Jun 25, 2024 |
| Title |
The influence of TFEB on gene expression in primary murine germinal center and non-germinal center B cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate TFEB-dependent mRNA expression in murine B cells, FACS-sorted germinal center and non-germinal center B lymphocytes of B-cell-specific conditional TFEB KO mice and control littermates were subjected to RNA sequencing analysis
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for FACS-sorted germinal center (CD19+GL7+CD95+) and non-germinal center (CD19+GL7-CD95-) B cells of conditional TFEB KO mice (Tfeb fl/fl Mb1-Cre +/-) and control littermates (Tfeb fl/fl Mb1-Cre -/-)
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| Contributor(s) |
Münchhalfen M, Görg R, Haberl M, Salinas G |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jul 19, 2023 |
| Last update date |
Jun 25, 2024 |
| Contact name |
Gabriela Salinas |
| E-mail(s) |
Gabriela.Salinas-Riester@medizin.uni-goettingen.de
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| Organization name |
Universitaetsmedizin Goettingen
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| Department |
Department of Pathology
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| Lab |
NGS Integrative Genomics
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| Street address |
Kreuzbergring 57
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| City |
Goettingen |
| State/province |
Lower-Saxony |
| ZIP/Postal code |
37075 |
| Country |
Germany |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (21)
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| GSM7653637 |
B cells, spleen, TFEB-KO, rep3 |
| GSM7653638 |
B cells, spleen, TFEB-WT, rep2 |
| GSM7653639 |
B cells, spleen, TFEB-KO, rep4 |
| GSM7653640 |
B cells, spleen, TFEB-WT, rep3 |
| GSM7653641 |
B cells, spleen, TFEB-WT, rep4 |
| GSM7653642 |
B cells, spleen, TFEB-KO, rep5 |
| GSM7653643 |
B cells, spleen, TFEB-WT, rep5 |
| GSM7653644 |
B cells, spleen, TFEB-KO, rep6 |
| GSM7653645 |
germinal center B cells, spleen, TFEB-KO, rep1 |
| GSM7653646 |
germinal center B cells, spleen, TFEB-KO, rep2 |
| GSM7653647 |
germinal center B cells, spleen, TFEB-WT, rep1 |
| GSM7653648 |
germinal center B cells, spleen, TFEB-KO, rep3 |
| GSM7653649 |
germinal center B cells, spleen, TFEB-WT, rep2 |
| GSM7653650 |
germinal center B cells, spleen, TFEB-KO, rep4 |
| GSM7653651 |
germinal center B cells, spleen, TFEB-WT, rep3 |
| GSM7653652 |
germinal center B cells, spleen, TFEB-KO, rep5 |
| GSM7653653 |
germinal center B cells, spleen, TFEB-WT, rep4 |
| GSM7653654 |
germinal center B cells, spleen, TFEB-KO, rep6 |
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| Relations |
| BioProject |
PRJNA996635 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE237799_kallisto_normalized_abundances.tsv.gz |
52.1 Mb |
(ftp)(http) |
TSV |
| GSE237799_salmon_raw_counts.tsv.gz |
572.9 Kb |
(ftp)(http) |
TSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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