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Status |
Public on Aug 24, 2011 |
Title |
Gene expression data of BCR-ABL1 transformed myeloid cells from BCL6 wild-type and BCL6 knockout mice treated with and without Imatinib and RI-BPI |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
To identify differences in the gene regulation between BCL6+/+ and BCL6-/- CML cells a gene expression analysis has been performed. We investigated the gene expression pattern in BCL6+/+ cells in the presence or absence of Imatinib and a combination of Imatinib and RI-BPI (a novel retro-inverso BCL6 peptide inhibitor). In BCL6-/- CML cells, we investigated the gene expression pattern in the presence or absence of Imatinib.
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Overall design |
BCR-ABL1 transformed myeloid cells from BCL6+/+ mice were cultured in the presence or absence of 10µM Imatinib or 10µM Imatinib and 20µM RI-BPI for 16 hours. BCR-ABL1 transformed myeloid cells from BCL6-/- mice were cultured in the presence or absence of 10µM Imatinib. Two samples for each condition were processed.
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Contributor(s) |
Hurtz C |
Citation(s) |
21911423 |
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Submission date |
Oct 19, 2010 |
Last update date |
Feb 11, 2019 |
Contact name |
Markus Müschen |
E-mail(s) |
mmuschen@chla.usc.edu
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Phone |
+ 1 323 361 5592
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Fax |
+1 323 361 1516
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URL |
http://www.lymphocytes.de/
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Organization name |
University of Southern California
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Department |
Childrens Hospital Los Angeles
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Lab |
Müschen Lab
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Street address |
4650 Sunset Blvd
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City |
Los Angeles |
State/province |
CA |
ZIP/Postal code |
90027 |
Country |
USA |
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Platforms (1) |
GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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Samples (10)
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Relations |
BioProject |
PRJNA132311 |