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Series GSE28551 Query DataSets for GSE28551
Status Public on Apr 13, 2011
Title Global placental gene expression profiling in the first and third trimesters of normal human pregnancy
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The human placenta is a rapidly developing organ with a relatively short life span that performs multiple functions until birth. Investigations into molecular mechanisms that control placental plasticity during its maturation might be useful in understanding patho-physiology of pregnancy-specific disorders. We hypothesized that molecular rearrangements and phenotypic adaptations that are necessary for normal placental development and maturation are reflected in its genotype. Our objective was to investigate global gene expression profile in the first and third trimester normal human placentas.
 
Overall design 21 women were recruited with uncomplicated pregnancies that were delivered at term and 16 healthy women undergoing surgical abortion at 9-12 weeks gestation. We compared global placental gene expression profile by Human Genome Survey Microarray v.2.0 (Applied Biosystems). A total of 37 hybridisations were performed applying direct comparison design.
 
Contributor(s) Paulssen RH, Fenton C, Sitras V, Vårtun A, Acharya G
Citation(s) 22442682
Submission date Apr 12, 2011
Last update date Jan 27, 2016
Contact name Chris Fenton
E-mail(s) chrisf@fagmed.uit.no
Phone 776 481 96479
Organization name UITO
Department Microarray
Lab Microarray
Street address Thor Knutsen vg 6
City Tromsø
ZIP/Postal code 9007
Country Norway
 
Platforms (1)
GPL2986 ABI Human Genome Survey Microarray Version 2
Samples (37)
GSM707051 placenta normal first trimester rep.1
GSM707052 placenta normal first trimester rep.2
GSM707053 placenta normal first trimester rep.3
Relations
BioProject PRJNA139065

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28551_RAW.tar 26.9 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
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