|
| Status |
Public on Mar 22, 2013 |
| Title |
Profiling pancreatic islets from obese db/db and lean control db/+ mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
This program addresses the molecular basis of beta-cell failure associated with the development of type 2 diabetes in the db/db mice. Specifically, which genes are differentially expressed in pancreatic islets of the db/db mice compared to the control db/+ mice?
|
| |
|
| Overall design |
The db/db mice islets profiling data was analyzed by identifying genes that were up- and down-regulated at selected p value and fold change in the islets of db/db mice compared to the corresponding db/+ controls.
|
| |
|
| Contributor(s) |
Wang I, Zhang B |
| Citation(s) |
22806142 |
| |
| Submission date |
Sep 07, 2011 |
| Last update date |
Mar 22, 2013 |
| Contact name |
I-Ming Wang |
| E-mail(s) |
i_ming_wang@merck.com
|
| Phone |
215-652-1287
|
| Organization name |
Merck Research Lab
|
| Department |
Genetics and Pharmacogenomics
|
| Lab |
Discovery Pharmacogenomics
|
| Street address |
770 Sumneytown Pike
|
| City |
West Point |
| State/province |
PA |
| ZIP/Postal code |
19486 |
| Country |
USA |
| |
|
| Platforms (1) |
|
| Samples (10)
|
|
| This SubSeries is part of SuperSeries: |
| GSE31559 |
Various mice and rat tissues subjected to various treatments |
|
| Relations |
| BioProject |
PRJNA155281 |
Less...
More...