|
| Status |
Public on May 01, 2012 |
| Title |
Comparison of gene expression between wild type and AP2-G KO parasites. |
| Platform organism |
Plasmodium berghei ANKA |
| Sample organism |
Plasmodium berghei |
| Experiment type |
Expression profiling by array
|
| Summary |
In the rodent malaria parasite Plasmodium berghei, we found that an AP2 family transcription factor designated AP2-L plays a critical role in the development of the liver stage. Using DNA microarray analysis we showed that the expression of several genes, including those of parasitophorous vacuole membrane proteins, was significantly decreased in the early liver stage of AP2-L-depleted parasites.
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|
| Overall design |
Gene expression of P. berghei sporozoites was compared between wild type and AP2-G KO parasites. Five biologically independent experiments were performed for each genotype.
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|
| Contributor(s) |
Yuda M, kaneko I |
| Citation(s) |
23144823 |
| |
| Submission date |
Jan 03, 2012 |
| Last update date |
Oct 27, 2014 |
| Contact name |
masao yuda |
| E-mail(s) |
m-yuda@doc.medic.mie-u.ac.jp
|
| Organization name |
mie university
|
| Street address |
edobashi 2-174
|
| City |
tsu |
| State/province |
mie |
| ZIP/Postal code |
514-0001 |
| Country |
Japan |
| |
|
| Platforms (1) |
|
| Samples (10)
|
| GSM855666 |
wild type salivary gland sporozoite 1 |
| GSM855667 |
wild type salivary gland sporozoite 2 |
| GSM855668 |
wild type salivary gland sporozoite 3 |
| GSM855669 |
wild type salivary gland sporozoite 4 |
| GSM855670 |
wild type salivary gland sporozoite 5 |
| GSM855671 |
AP2-G KO salivary gland sporozoite 1 |
| GSM855672 |
AP2-G KO salivary gland sporozoite 2 |
| GSM855673 |
AP2-G KO salivary gland sporozoite 3 |
| GSM855674 |
AP2-G KO salivary gland sporozoite 4 |
| GSM855675 |
AP2-G KO salivary gland sporozoite 5 |
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| This SubSeries is part of SuperSeries: |
| GSE34878 |
Identification of a Transcription Factor That Is Critical for Malaria Liver Stage Development |
|
| Relations |
| BioProject |
PRJNA156295 |
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