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Status |
Public on Mar 01, 2012 |
Title |
Fibroblasts under adipogenic, chondrogenic or osteogenic differentiation medium and controls |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Global gene expression analysis was performed to investigate the changes of the fibroblast phenotype after four-week inductions toward adipocytic, osteoblastic and chondrocytic lineages. Human cells. Differential gene regulation, interpreted through Gene Set Enrichment Analysis, highlight important similarities and differences of induced fibroblasts compared to control cultures of human fibroblasts, adipocytes, osteoblasts and articular chondrocytes.
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Overall design |
Fibroblast controls were compared to Adipogenic induced fibroblasts and adipocytes. Gene sets were analysed with GSEA (webgestalt). Repeated for each lineage.
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Contributor(s) |
Rakar J |
Citation(s) |
23023066 |
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Submission date |
Feb 03, 2012 |
Last update date |
Jul 26, 2018 |
Contact name |
Stefan Thor |
E-mail(s) |
s.thor@uq.edu.au
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Organization name |
The University of Queensland
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Department |
School of Biomedical Sciences
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Street address |
Skerman Bldg (65) room 506 Faculty of Medicine
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City |
Brisbane |
State/province |
QLD |
ZIP/Postal code |
4072 |
Country |
Australia |
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Platforms (1) |
GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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Samples (14)
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Relations |
BioProject |
PRJNA152277 |